(Q39854226)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19428368%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

title

Suppression of topoisomerase IIalpha expression and function in human cells decreases chromosomal radiosensitivity (English)

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27 January 2020

1

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27 January 2020

author name string

Andrew C Riches

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19428368%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Peter E Bryant

series ordinal

3

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27 January 2020

language of work or name

English

0 references

publication date

4 February 2009

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27 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19428368%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

volume

663

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27 January 2020

issue

1-2

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27 January 2020

page(s)

40-45

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Topoisomerase II inhibitors affect entry into mitosis and chromosome condensation in BHK cells.

27 January 2020

cites work

1 reference

12 December 2020

Identification of differentially expressed genes in human prostate cancer using subtraction and microarray.

1 reference

12 December 2020

DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe

1 reference

12 December 2020

Localisation of DNA topoisomerase IIalpha in mouse erythroleukemia cells

1 reference

12 December 2020

Increased G2 chromosomal radiosensitivity in cancer patients: the role of cdk1/cyclin-B activity level in the mechanisms involved

1 reference

12 December 2020

Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives

1 reference

12 December 2020

Eukaryotic DNA topoisomerase II beta

1 reference

12 December 2020

Increased chromosomal radiosensitivity in breast cancer patients: a comparison of two assays

1 reference

12 December 2020

Activation of topoisomerase II-mediated excision of chromosomal DNA loops during oxidative stress.

1 reference

12 December 2020

Sensitivity to radiation-induced chromosome damage may be a marker of genetic predisposition in young head and neck cancer patients

1 reference

12 December 2020

Enhanced chromosomal radiosensitivity in peripheral blood lymphocytes of larynx cancer patients

1 reference

12 December 2020

Cell cycle-dependent DNA damage signaling induced by ICRF-193 involves ATM, ATR, CHK2, and BRCA1.

1 reference

12 December 2020

DNA topoisomerase IIbeta and neural development

1 reference

12 December 2020

DNA topoisomerase poisons as antitumor drugs

1 reference

12 December 2020

A role for topoisomerase II alpha in the formation of radiation-induced chromatid breaks

1 reference

12 December 2020

Resolving the role of topoisomerase II in chromatin structure and function

1 reference

12 December 2020

Effect of antineoplastic agents on the DNA cleavage/religation reaction of eukaryotic topoisomerase II: inhibition of DNA religation by etoposide.

1 reference

12 December 2020

Chromosomal radiosensitivity as a marker of predisposition to common cancers?

1 reference

12 December 2020

DNA topoisomerase II, genotoxicity, and cancer

1 reference

12 December 2020

1 reference

12 December 2020

DNA repair proficiency in breast cancer patients and their first-degree relatives

1 reference

12 December 2020

Chromosomal radiosensitivity in G2-phase lymphocytes identifies breast cancer patients with distinctive tumour characteristics

1 reference

12 December 2020

Chromosomal radiosensitivity in breast cancer patients with a known or putative genetic predisposition

1 reference

12 December 2020

Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II

1 reference

12 December 2020

Chromosomal radiosensitivity in head and neck cancer patients: evidence for genetic predisposition?

1 reference

12 December 2020

Distinct roles of Topoisomerase II isoforms: DNA damage accelerating alpha, double strand break repair promoting beta

1 reference

12 December 2020

Abasic sites stimulate double-stranded DNA cleavage mediated by topoisomerase II. DNA lesions as endogenous topoisomerase II poisons

1 reference

12 December 2020

Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation

1 reference

12 December 2020

Progress towards understanding the nature of chromatid breakage

1 reference

12 December 2020

Variability of G(2) checkpoint sensitivity to low doses of X-rays (2 cGy): correlation with G(2) chromatid aberrations but not with an adaptive response

1 reference

12 December 2020

Plk1 depletion in nontransformed diploid cells activates the DNA-damage checkpoint

1 reference

12 December 2020

Radiation-induced chromatid breaks as a predictor of breast cancer risk

1 reference

12 December 2020

Deficient DNA repair capacity, a predisposing factor in breast cancer

1 reference

12 December 2020

The XRCC2 human repair gene influences recombinational rearrangements leading to chromatid breaks

1 reference

12 December 2020

Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp

1 reference

12 December 2020

Structural organization of the human TOP2A and TOP2B genes.

1 reference

12 December 2020

DNA topoisomerases: essential enzymes and lethal targets

1 reference

12 December 2020

Mechanisms of chromosomal aberration production. 3. Chemicals and ionizing radiation

1 reference

12 December 2020

Chromosomal radiosensitivity in breast cancer patients: influence of age of onset of the disease.

1 reference

12 December 2020

Differential sensitivities of recombinant human topoisomerase IIalpha and beta to various classes of topoisomerase II-interacting agents

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12 December 2020

Investigating the nature of chromatid breaks produced by restriction endonucleases

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12 December 2020

Mitoxantrone resistance in HL-60 leukemia cells: reduced nuclear topoisomerase II catalytic activity and drug-induced DNA cleavage in association with reduced expression of the topoisomerase II beta isoform

1 reference

12 December 2020

Sensitivity of human type II topoisomerases to DNA damage: stimulation of enzyme-mediated DNA cleavage by abasic, oxidized and alkylated lesions

1 reference

12 December 2020

The G2 chromosomal radiosensitivity assay

1 reference

12 December 2020

Heritability of cellular radiosensitivity: a marker of low-penetrance predisposition genes in breast cancer?

1 reference

12 December 2020

Elevated G2 chromosomal radiosensitivity in Irish breast cancer patients: a comparison with other studies

1 reference

12 December 2020

Proliferation- and cell cycle-dependent differences in expression of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells

1 reference

12 December 2020

The signal model: a possible explanation for the conversion of DNA double-strand breaks into chromatid breaks

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12 December 2020

Topoisomerase II and the etiology of chromosomal translocations

1 reference

12 December 2020

Genetic predisposition in breast cancer

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12 December 2020

Nuclear topoisomerase II levels correlate with the sensitivity of mammalian cells to intercalating agents and epipodophyllotoxins.

1 reference

12 December 2020

10.1016/J.MRFMMM.2009.01.003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19428368%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19428368%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

19428368

1 reference