(Q39854925)

15 September 2017

Functional relevance of aromatic residues in the first transmembrane domain of P2X receptors (English)

1 reference

15 September 2017

transmembrane protein

0 references

author name string

Marie Jindrichova

1

1 reference

15 September 2017

Vojtech Vavra

2

1 reference

15 September 2017

Tomas Obsil

3

1 reference

15 September 2017

Stanko S Stojilkovic

4

1 reference

15 September 2017

Hana Zemkova

5

1 reference

15 September 2017

language of work or name

English

0 references

publication date

1 May 2009

1 reference

Journal of Neurochemistry

15 September 2017

1 reference

15 September 2017

109

1 reference

15 September 2017

3

1 reference

15 September 2017

923-934

1 reference

The P2X7 receptor channel pore dilates under physiological ion conditions

15 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Gating the pore of P2X receptor channels

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Identification of P2X(4) receptor transmembrane residues contributing to channel gating and interaction with ivermectin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

On the role of the first transmembrane domain in cation permeability and flux of the ATP-gated P2X2 receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Thr339-to-serine substitution in rat P2X2 receptor second transmembrane domain causes constitutive opening and indicates a gating role for Lys308.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Acidic amino acids impart enhanced Ca2+ permeability and flux in two members of the ATP-gated P2X receptor family

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Identification of an intersubunit cross-link between substituted cysteine residues located in the putative ATP binding site of the P2X1 receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

P2X5 subunit assembly requires scaffolding by the second transmembrane domain and a conserved aspartate

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Identification of P2X4 receptor-specific residues contributing to the ivermectin effects on channel deactivation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Role of ectodomain lysines in the subunits of the heteromeric P2X2/3 receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Secondary structure and gating rearrangements of transmembrane segments in rat P2X4 receptor channels

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Molecular determinants of the agonist binding domain of a P2X receptor channel.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Molecular properties of ATP-gated P2X receptor ion channels

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Contribution of transmembrane regions to ATP-gated P2X2 channel permeability dynamics

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Gain and loss of channel function by alanine substitutions in the transmembrane segments of the rat ATP-gated P2X2 receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Contribution of calcium ions to P2X channel responses.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Mechanism of ivermectin facilitation of human P2X4 receptor channels

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Subunit Arrangement in P2X Receptors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Functional evidence of distinct ATP activation sites at the human P2X(7) receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Polar residues of the second transmembrane domain influence cation permeability of the ATP-gated P2X(2) receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Molecular and functional characterization of human P2X(2) receptors.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Receptors for purines and pyrimidines

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

A new class of ligand-gated ion channel defined by P2X receptor for extracellular ATP

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Acetylcholine receptor channel structure probed in cysteine-substitution mutants.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

On the contribution of the first transmembrane domain to whole-cell current through an ATP-gated ionotropic P2X receptor.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Amino acid residues involved in gating identified in the first membrane-spanning domain of the rat P2X(2) receptor

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Membrane topology of an ATP-gated ion channel (P2X receptor).

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Topological analysis of the ATP-gated ionotropic [correction of ionotrophic] P2X2 receptor subunit

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Identification of amino acid residues contributing to the pore of a P2X receptor

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Ivermectin Interaction with transmembrane helices reveals widespread rearrangements during opening of P2X receptor channels

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

The first transmembrane domain of the P2X receptor subunit participates in the agonist-induced gating of the channel

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Identification of Amino Acid Residues Contributing to the ATP-binding Site of a Purinergic P2X Receptor

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2727158

Amino Acid Residues in the P2X7 Receptor that Mediate Differential Sensitivity to ATP and BzATP

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19425179

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A domain contributing to the ion channel of ATP-gated P2X2 receptors identified by the substituted cysteine accessibility method

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19425179

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification of a domain involved in ATP-gated ionotropic receptor subunit assembly

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19425179

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1471-4159.2009.06021.X

1 reference

15 September 2017

1 reference

15 September 2017

1 reference