(Q39859695)

15 September 2017

Cell culture-adaptive mutations in the NS5B gene of hepatitis C virus with delayed replication and reduced cytotoxicity (English)

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15 September 2017

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Ju-Il Kang

1

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15 September 2017

Jungsuh P Kim

series ordinal

2

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15 September 2017

Takaji Wakita

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3

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15 September 2017

Byung-Yoon Ahn

series ordinal

4

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15 September 2017

15 April 2009

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15 September 2017

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15 September 2017

144

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15 September 2017

1-2

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15 September 2017

107-116

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Cell culture-adaptive NS3 mutations required for the robust replication of genome-length hepatitis C virus RNA.

15 September 2017

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Novel insights into hepatitis C virus replication and persistence

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Efficient initiation of HCV RNA replication in cell culture

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Robust production of infectious hepatitis C virus (HCV) from stably HCV cDNA-transfected human hepatoma cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

The hepatitis C virus core protein interacts with NS5A and activates its caspase-mediated proteolytic cleavage

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Viruses, endoplasmic reticulum stress, and interferon responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

An in vitro model of hepatitis C virion production

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

The NS5A protein of the hepatitis C virus genotype 1a is cleaved by caspases to produce C-terminal-truncated forms of the protein that reside mainly in the cytosol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Calcium-dependent calpain proteases are implicated in processing of the hepatitis C virus NS5A protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Efficient replication of the genotype 2a hepatitis C virus subgenomic replicon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Sequence analysis of hepatitis C virus isolated from a fulminant hepatitis patient

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Hepatitis C virus infection

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Complete replication of hepatitis C virus in cell culture

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Unravelling hepatitis C virus replication from genome to function

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Intragenotypic JFH1 based recombinant hepatitis C virus produces high levels of infectious particles but causes increased cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Effect of cell growth on hepatitis C virus (HCV) replication and a mechanism of cell confluence-based inhibition of HCV RNA and protein expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

A recombinant hepatitis C virus RNA-dependent RNA polymerase capable of copying the full-length viral RNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Development of plaque assays for hepatitis C virus-JFH1 strain and isolation of mutants with enhanced cytopathogenicity and replication capacity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

The lipid droplet binding domain of hepatitis C virus core protein is a major determinant for efficient virus assembly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Effect of interaction between hepatitis C virus NS5A and NS5B on hepatitis C virus RNA replication with the hepatitis C virus replicon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Hepatitis C virus (HCV) NS5A binds RNA-dependent RNA polymerase (RdRP) NS5B and modulates RNA-dependent RNA polymerase activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Apoptotic DNA fragmentation is detected by a semi-quantitative ligation-mediated PCR of blunt DNA ends

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

RNA-dependent RNA polymerase activity of the soluble recombinant hepatitis C virus NS5B protein truncated at the C-terminal region

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Compensatory Mutations in E1, p7, NS2, and NS3 Enhance Yields of Cell Culture-Infectious Intergenotypic Chimeric Hepatitis C Virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

High-efficiency gene transfection by in situ electroporation of cultured cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Robust hepatitis C virus infection in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

Persistent Hepatitis C Virus Infection In Vitro: Coevolution of Virus and Host

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.002

10.1016/J.VIRUSRES.2009.04.002

7 January 2021

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DOI

1 reference

15 September 2017

1 reference