(Q39867703)

15 September 2017

Identification of loss of function mutations in human genes encoding RIG-I and MDA5: implications for resistance to type I diabetes (English)

1 reference

15 September 2017

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5

1 reference

15 September 2017

Taeko Shigemoto

1

1 reference

15 September 2017

Maiko Kageyama

2

1 reference

15 September 2017

Reiko Hirai

3

1 reference

15 September 2017

Jiping Zheng

4

1 reference

15 September 2017

Takashi Fujita

6

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15 September 2017

language of work or name

English

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publication date

26 March 2009

1 reference

Journal of Biological Chemistry

15 September 2017

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15 September 2017

284

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15 September 2017

20

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15 September 2017

13348-13354

1 reference

The RIG-I-like receptor LGP2 recognizes the termini of double-stranded RNA

15 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679434

Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679434

Structural mechanism of RNA recognition by the RIG-I-like receptors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679434

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679434

The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679434

Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679434

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679434

Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679434

5'-Triphosphate RNA is the ligand for RIG-I

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679434

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679434

Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679434

A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679434

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679434

Pathogen recognition and innate immunity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679434

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679434

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679434

Antiviral actions of interferons

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2679434

22 September 2017

Identifiers

DOI

10.1074/JBC.M809449200

1 reference

15 September 2017

1 reference

15 September 2017

PubMed publication ID

19324880

1 reference