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Identification of a promoter-specific transactivation domain in the herpes simplex virus regulatory protein ICP4.
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Europe PubMed Central
PMC publication ID
191244
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9032304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
title
Identification of a promoter-specific transactivation domain in the herpes simplex virus regulatory protein ICP4
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
191244
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9032304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
author name string
W Xiao
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
191244
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9032304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
L I Pizer
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
191244
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9032304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
K W Wilcox
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
191244
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9032304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
language of work or name
English
0 references
publication date
1 March 1997
1 reference
stated in
Europe PubMed Central
PMC publication ID
191244
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9032304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
published in
Journal of Virology
1 reference
stated in
Europe PubMed Central
PMC publication ID
191244
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9032304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
volume
71
1 reference
stated in
Europe PubMed Central
PMC publication ID
191244
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9032304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
issue
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
191244
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9032304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
page(s)
1757-1765
1 reference
stated in
Europe PubMed Central
PMC publication ID
191244
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9032304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
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EBNA-2 of herpesvirus papio diverges significantly from the type A and type B EBNA-2 proteins of Epstein-Barr virus but retains an efficient transactivation domain with a conserved hydrophobic motif.
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Localization of a 34-amino-acid segment implicated in dimerization of the herpes simplex virus type 1 ICP4 polypeptide by a dimerization trap.
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Mapping of intracellular localization domains and evidence for colocalization interactions between the IE110 and IE175 nuclear transactivator proteins of herpes simplex virus.
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The DNA binding domains of the varicella-zoster virus gene 62 and herpes simplex virus type 1 ICP4 transactivator proteins heterodimerize and bind to DNA.
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Requirements for activation of the herpes simplex virus glycoprotein C promoter in vitro by the viral regulatory protein ICP4.
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Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein
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Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4.
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The regions of the herpes simplex virus type 1 immediate early protein Vmw175 required for site specific DNA binding closely correspond to those involved in transcriptional regulation
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Cell lines containing varicella-zoster virus open reading frame 62 and expressing the "IE" 175 protein complement ICP4 mutants of herpes simplex virus type 1.
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22 September 2017
Association of herpes simplex virus regulatory protein ICP4 with sequences spanning the ICP4 gene transcription initiation site
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22 September 2017
Physical and functional domains of the herpes simplex virus transcriptional regulatory protein ICP4.
1 reference
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PubMed Central
reference URL
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22 September 2017
Separation of primary structural components conferring autoregulation, transactivation, and DNA-binding properties to the herpes simplex virus transcriptional regulatory protein ICP4
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PubMed Central
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22 September 2017
Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins
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22 September 2017
DNA nucleotide sequence analysis of the immediate-early gene of pseudorabies virus
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22 September 2017
ICP4-binding sites in the promoter and coding regions of the herpes simplex virus gD gene contribute to activation of in vitro transcription by ICP4
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22 September 2017
The major transcriptional regulatory protein of herpes simplex virus type 1 includes a protease resistant DNA binding domain
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PubMed Central
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22 September 2017
Functional relevance of specific interactions between herpes simplex virus type 1 ICP4 and sequences from the promoter-regulatory domain of the viral thymidine kinase gene
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22 September 2017
Codons 262 to 490 from the herpes simplex virus ICP4 gene are sufficient to encode a sequence-specific DNA binding protein
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PubMed Central
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22 September 2017
The conserved DNA-binding domains encoded by the herpes simplex virus type 1 ICP4, pseudorabies virus IE180, and varicella-zoster virus ORF62 genes recognize similar sites in the corresponding promoters
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22 September 2017
The functionally active IE2 immediate-early regulatory protein of human cytomegalovirus is an 80-kilodalton polypeptide that contains two distinct activator domains and a duplicated nuclear localization signal
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PubMed Central
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22 September 2017
Immobilized metal ion affinity chromatography
1 reference
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PubMed Central
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22 September 2017
Herpes simplex virus type 1 polypeptide ICP4 bends DNA
1 reference
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PubMed Central
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22 September 2017
The ICP4 binding sites in the herpes simplex virus type 1 glycoprotein D (gD) promoter are not essential for efficient gD transcription during virus infection
1 reference
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PubMed Central
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22 September 2017
General initiation factors for RNA polymerase II.
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25 September 2017
A herpes simplex virus type 1 recombinant with both copies of the Vmw175 coding sequences replaced by the homologous varicella-zoster virus open reading frame
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PubMed Central
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25 September 2017
Initiation of transcription by RNA polymerase II: a multi-step process.
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PubMed Central
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15 June 2018
Transcriptional activation modulated by homopolymeric glutamine and proline stretches
1 reference
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PubMed Central
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15 June 2018
Promoter, spliced leader, and coding sequence for BICP4, the largest of the immediate-early proteins of bovine herpesvirus 1.
1 reference
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PubMed Central
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15 June 2018
Evolutionary comparisons of the S segments in the genomes of herpes simplex virus type 1 and varicella-zoster virus
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15 June 2018
A herpes simplex virus type 1 mutant with a deletion in the polypeptide-coding sequences of the ICP4 gene
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15 June 2018
Promoter sequence and cell type can dramatically affect the efficiency of transcriptional activation induced by herpes simplex virus type 1 and its immediate-early gene products Vmw175 and Vmw110.
1 reference
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PubMed Central
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15 June 2018
DNA sequence and comparative analyses of the equine herpesvirus type 1 immediate early gene
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15 June 2018
Transcriptional activation by the pseudorabies virus immediate early protein
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191244
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15 June 2018
A prominent serine-rich region in Vmw175, the major transcriptional regulator protein of herpes simplex virus type 1, is not essential for virus growth in tissue culture
1 reference
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PubMed Central
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15 June 2018
Interaction of cell and virus proteins with DNA sequences encompassing the promoter/regulatory and leader regions of the herpes simplex virus thymidine kinase gene.
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PubMed Central
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15 June 2018
Characterization of DNA-protein complex formation in nuclear extracts with a sequence from the herpes simplex virus thymidine kinase gene
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15 June 2018
GAL4 derivatives function alone and synergistically with mammalian activators in vitro
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Mutational dissection of the HSV-1 immediate-early protein Vmw175 involved in transcriptional transactivation and repression
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/9032304
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The equine herpesvirus type 1 immediate-early gene product contains an acidic transcriptional activation domain
1 reference
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PubMed
reference URL
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Nef protein of HIV-1 is a transcriptional repressor of HIV-1 LTR
1 reference
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based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/JVI.71.3.1757-1765.1997
0 references
PMC publication ID
191244
1 reference
stated in
Europe PubMed Central
PMC publication ID
191244
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9032304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
PubMed publication ID
9032304
1 reference
stated in
Europe PubMed Central
PMC publication ID
191244
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9032304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
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