(Q39878922)

English

Regulation of GAP-43 at serine 41 acts as a switch to modulate both intrinsic and extrinsic behaviors of growing neurons, via altered membrane distribution

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Regulation of GAP-43 at serine 41 acts as a switch to modulate both intrinsic and extrinsic behaviors of growing neurons, via altered membrane distribution (English)

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

author name string

Lilly Nguyen

1

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Qin He

2

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Karina F Meiri

3

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

publication date

26 February 2009

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Molecular and Cellular Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

41

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

1

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

62-73

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

The neural cell adhesion molecule NCAM and lipid rafts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Role of the growth-associated protein GAP-43 in NCAM-mediated neurite outgrowth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

GAP-43 is essential for the neurotrophic effects of BDNF and positive AMPA receptor modulator S18986.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Neurotrophin-dependent dendritic filopodial motility: a convergence on PI3K signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Molecular mechanisms of axonal growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

GAP-43 is key to mitotic spindle control and centrosome-based polarization in neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Actin-binding proteins take the reins in growth cones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Role of GAP-43 in sequestering phosphatidylinositol 4,5-bisphosphate to Raft bilayers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Lipid rafts in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

The neural cell adhesion molecule NCAM regulates neuritogenesis by multiple mechanisms of interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

DCC association with lipid rafts is required for netrin-1-mediated axon guidance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Spatial control of actin-based motility through plasmalemmal PtdIns(4,5)P2-rich raft assemblies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Mass spectrometric analysis of GAP-43/neuromodulin reveals the presence of a variety of fatty acylated species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Growth-associated protein-43 is required for commissural axon guidance in the developing vertebrate nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

New EMBO members' review: actin cytoskeleton regulation through modulation of PI(4,5)P(2) rafts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Involvement of CD44 in cytoskeleton rearrangement and raft reorganization in T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Cholesterol and caveolae: structural and functional relationships

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

PSD-95 involvement in maturation of excitatory synapses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Caveolins, liquid-ordered domains, and signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Association of GAP-43 with detergent-resistant membranes requires two palmitoylated cysteine residues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

The neuronal growth-associated protein GAP-43 interacts with rabaptin-5 and participates in endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Association of Engrailed homeoproteins with vesicles presenting caveolae-like properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Phosphorylation-site mutagenesis of the growth-associated protein GAP-43 modulates its effects on cell spreading and morphology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Growth-associated protein, GAP-43, a polypeptide that is induced when neurons extend axons, is a component of growth cones and corresponds to pp46, a major polypeptide of a subcellular fraction enriched in growth cones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

GAP-43 in growth cones is associated with areas of membrane that are tightly bound to substrate and is a component of a membrane skeleton subcellular fraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

Monoclonal antibodies show that kinase C phosphorylation of GAP-43 during axonogenesis is both spatially and temporally restricted in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

22 September 2017

De novo formation of focal complex-like structures in host cells by invading Streptococci.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

25 September 2017

GAP43, MARCKS, and CAP23 modulate PI(4,5)P(2) at plasmalemmal rafts, and regulate cell cortex actin dynamics through a common mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

25 September 2017

B-50/GAP-43 potentiates cytoskeletal reorganization in raft domains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

25 September 2017

Bifunctional protein cross-linking reagents improve labeling of cytoskeletal proteins for qualitative and quantitative fluorescence microscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

25 September 2017

Organization of actin networks in intact filopodia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

17 June 2018

Biochemical characterization of detergent-resistant membranes: a systematic approach.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

17 June 2018

Cosignaling of NCAM via lipid rafts and the FGF receptor is required for neuritogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

17 June 2018

Isolation and characterization of detergent-resistant microdomains responsive to NCAM-mediated signaling from growth cones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

17 June 2018

Neurite outgrowth stimulated by neural cell adhesion molecules requires growth-associated protein-43 (GAP-43) function and is associated with GAP-43 phosphorylation in growth cones.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

17 June 2018

Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

17 June 2018

The motility-associated proteins GAP-43, MARCKS, and CAP-23 share unique targeting and surface activity-inducing properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

17 June 2018

Depletion of 43-kD growth-associated protein in primary sensory neurons leads to diminished formation and spreading of growth cones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

17 June 2018

Differential expression of alpha-subunits of G-proteins in human neuroblastoma-derived cell clones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

17 June 2018

Protein kinase C in rat brain synaptosomes. Beta II-subspecies as a major isoform associated with membrane-skeleton elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

17 June 2018

Isolation and use of rafts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

20 August 2018

GAP-43 regulates NCAM-180-mediated neurite outgrowth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

20 August 2018

GAP-43 heterozygous mice show delayed barrel patterning, differentiation of radial glia, and downregulation of GAP-43.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

20 August 2018

Lipid rafts mediate chemotropic guidance of nerve growth cones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

20 August 2018

Abnormal thalamocortical pathfinding and terminal arbors lead to enlarged barrels in neonatal GAP-43 heterozygous mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

20 August 2018

Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

20 August 2018

Normal Arp2/3 complex activation in platelets lacking WASp.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

20 August 2018

Developmental changes in the protein composition of sphingolipid- and cholesterol-enriched membrane domains of rat cerebellar granule cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

20 August 2018

bFGF stimulates GAP-43 phosphorylation at ser41 and modifies its intracellular localization in cultured hippocampal neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

20 August 2018

Distribution of phosphorylated GAP-43 (neuromodulin) in growth cones directly reflects growth cone behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

20 August 2018

Modulation of actin filament behavior by GAP-43 (neuromodulin) is dependent on the phosphorylation status of serine 41, the protein kinase C site.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

20 August 2018

Absence of persistent spreading, branching, and adhesion in GAP-43-depleted growth cones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

20 August 2018

Nerve growth factor stimulation of GAP-43 phosphorylation in intact isolated growth cones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

20 August 2018

Analysis of Raft Affinity of Membrane Proteins by Detergent-Insolubility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795319

2 December 2018

GAP-43 phosphorylation is dynamically regulated in individual growth cones

1 reference

https://pubmed.ncbi.nlm.nih.gov/19249369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B-50/GAP-43 binds to actin filaments without affecting actin polymerization and filament organization

1 reference

https://pubmed.ncbi.nlm.nih.gov/19249369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Participation of type II protein kinase A in the retinoic acid-induced growth inhibition of SH-SY5Y human neuroblastoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19249369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscarinic receptor-mediated inositol 1,4,5-trisphosphate formation in SH-SY5Y neuroblastoma cells is regulated acutely by cytosolic Ca2+ and by rapid desensitization

1 reference

https://pubmed.ncbi.nlm.nih.gov/19249369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19249369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutagenesis of ser41 to ala inhibits the association of GAP-43 with the membrane skeleton of GAP-43-deficient PC12B cells: effects on cell adhesion and the composition of neurite cytoskeleton and membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/19249369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Separation of "glycosphingolipid signaling domain" from caveolin-containing membrane fraction in mouse melanoma B16 cells and its role in cell adhesion coupled with signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/19249369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MCN.2009.01.011

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

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