(Q39883816)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19217788%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Synthesis and bioevaluation of omega-N-amino analogs of B13 (English)

1 reference

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21 January 2020

2

1 reference

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21 January 2020

author name string

Aiping Bai

1

1 reference

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21 January 2020

Jacek Bielawski

3

1 reference

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21 January 2020

Nalini Mayroo

4

1 reference

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21 January 2020

Xiang Liu

5

1 reference

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21 January 2020

James Norris

6

1 reference

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21 January 2020

Yusuf A Hannun

7

1 reference

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21 January 2020

Alicja Bielawska

8

1 reference

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21 January 2020

language of work or name

English

0 references

publication date

31 January 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19217788%20AND%20SRC:MED&resulttype=core&format=json

Bioorganic & Medicinal Chemistry

21 January 2020

published in

1 reference

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21 January 2020

volume

17

1 reference

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21 January 2020

issue

5

1 reference

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21 January 2020

page(s)

1840-1848

1 reference

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Ceramide-induced cell death in malignant cells

21 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

Acid ceramidase inhibition: a novel target for cancer therapy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

The functional effects of acid ceramidase overexpression in prostate cancer progression and resistance to chemotherapy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

Novel analogs of D-e-MAPP and B13. Part 2: signature effects on bioactive sphingolipids

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

Novel analogs of D-e-MAPP and B13. Part 1: synthesis and evaluation as potential anticancer agents

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): attenuation of C(18)-ceramide in HNSCC tumors correlates with lymphovascular invasion and nodal metastasis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

Lysosomotropic acid ceramidase inhibitor induces apoptosis in prostate cancer cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

Role of acid ceramidase in resistance to FasL: therapeutic approaches based on acid ceramidase inhibitors and FasL gene therapy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

Design, synthesis and activity as acid ceramidase inhibitors of 2-oxooctanoyl and N-oleoylethanolamine analogues

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

Acid ceramidase but not acid sphingomyelinase is required for tumor necrosis factor-{alpha}-induced PGE2 production.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

Molecular mechanisms of caspase regulation during apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

Biologically active sphingolipids in cancer pathogenesis and treatment

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

The ceramide analog, B13, induces apoptosis in prostate cancer cell lines and inhibits tumor growth in prostate cancer xenografts

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

Emerging roles of caspase-3 in apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

Bcl-2 overexpression prevents apoptosis induced by ceramidase inhibitors in malignant melanoma and HaCaT keratinocytes.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

Structural requirements of ceramide and sphingosine based inhibitors of mitochondrial ceramidase

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2696190

Preparation of radiolabeled ceramides and phosphosphingolipids

20 August 2018

1 reference

12 December 2020

Chemistry and Metabolism of Sphingolipids. 3-Oxo Derivatives of N-Acetylsphingosine and N-Acetyldihydrosphingosine

1 reference

12 December 2020

Ceramide-mediated biology. Determination of structural and stereospecific requirements through the use of N-acyl-phenylaminoalcohol analogs

1 reference

12 December 2020

Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide

1 reference

12 December 2020

Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry

1 reference

12 December 2020

10.1016/J.BMC.2009.01.057

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19217788%20AND%20SRC:MED&resulttype=core&format=json

release_wzxzcghve5gwfltdadpr2v6hzq

21 January 2020

Fatcat ID

0 references

1 reference

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21 January 2020

PubMed publication ID

19217788

1 reference