(Q39884127)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20381588%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

title

Genetic disruption of the autism spectrum disorder risk gene PLAUR induces GABAA receptor subunit changes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20381588%20AND%20SRC:MED&resulttype=core&format=json

Lisa Schlueter McFadyen-Ketchum

30 January 2020

main subject

autism spectrum disorder

0 references

autism

0 references

author

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20381588%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Shelley Russek

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20381588%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

David H Farb

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20381588%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

author name string

K L Eagleson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20381588%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

M C Gravielle

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20381588%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

P Levitt

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20381588%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

language of work or name

English

0 references

publication date

7 April 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20381588%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

number of pages

14

1 reference

inferred from page(s)

published in

Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20381588%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

volume

168

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20381588%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20381588%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

page(s)

797-810

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20381588%20AND%20SRC:MED&resulttype=core&format=json

Reduced conditioned fear response in mice that lack Dlx1 and show subtype-specific loss of interneurons

30 January 2020

cites work

1 reference

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Combined effect of neonatal immune activation and mutant DISC1 on phenotypic changes in adulthood

22 September 2017

1 reference

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Regionalized loss of parvalbumin interneurons in the cerebral cortex of mice with deficits in GFRalpha1 signaling.

22 September 2017

1 reference

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The cell-intrinsic requirement of Sox6 for cortical interneuron development

22 September 2017

1 reference

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Decreased GABAA receptors and benzodiazepine binding sites in the anterior cingulate cortex in autism

22 September 2017

1 reference

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Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry

22 September 2017

1 reference

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A triplet repeat expansion genetic mouse model of infantile spasms syndrome, Arx(GCG)10+7, with interneuronopathy, spasms in infancy, persistent seizures, and adult cognitive and behavioral impairment

22 September 2017

1 reference

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Genetic evidence implicating multiple genes in the MET receptor tyrosine kinase pathway in autism spectrum disorder

22 September 2017

1 reference

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Critical role of promoter IV-driven BDNF transcription in GABAergic transmission and synaptic plasticity in the prefrontal cortex.

22 September 2017

1 reference

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Protracted developmental trajectories of GABAA receptor alpha1 and alpha2 subunit expression in primate prefrontal cortex

22 September 2017

1 reference

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Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia

22 September 2017

1 reference

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The role of Slit-Robo signaling in the generation, migration and morphological differentiation of cortical interneurons

22 September 2017

1 reference

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Forebrain and midbrain distribution of major benzodiazepine-sensitive GABAA receptor subunits in the adult C57 mouse as assessed with in situ hybridization

22 September 2017

1 reference

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Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia

22 September 2017

1 reference

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Postnatal alterations of the inhibitory synaptic responses recorded from cortical pyramidal neurons in the Lis1/sLis1 mutant mouse

22 September 2017

1 reference

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Deciphering the disease process of schizophrenia: the contribution of cortical GABA neurons

22 September 2017

1 reference

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15q11-13 GABAA receptor genes are normally biallelically expressed in brain yet are subject to epigenetic dysregulation in autism-spectrum disorders

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Autism spectrum disorders: developmental disconnection syndromes

22 September 2017

1 reference

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GABA(A) receptor diversity and pharmacology

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

An inversion inv(4)(p12-p15.3) in autistic siblings implicates the 4p GABA receptor gene cluster

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Imidazenil and diazepam increase locomotor activity in mice exposed to protracted social isolation.

22 September 2017

1 reference

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Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Mice lacking Dlx1 show subtype-specific loss of interneurons, reduced inhibition and epilepsy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Ovarian cycle-linked changes in GABA(A) receptors mediating tonic inhibition alter seizure susceptibility and anxiety

22 September 2017

1 reference

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GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon.

22 September 2017

1 reference

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Cortical inhibitory neurons and schizophrenia

22 September 2017

1 reference

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Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3.

22 September 2017

1 reference

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Spatial analysis reveals alterations of parvalbumin- and calbindin-positive local circuit neurons in the cerebral cortex of mutant mdx mice

22 September 2017

1 reference

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Regulation of neocortical interneuron development and the implications for neurodevelopmental disorders.

22 September 2017

1 reference

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Changes in GABA(A) receptor gene expression associated with selective alterations in receptor function and pharmacology after ethanol withdrawal.

22 September 2017

1 reference

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Model of autism: increased ratio of excitation/inhibition in key neural systems

22 September 2017

1 reference

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Angelman syndrome reviewed from a neurophysiological perspective. The UBE3A-GABRB3 hypothesis

22 September 2017

1 reference

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Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia.

22 September 2017

1 reference

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Loss of the tailless gene affects forebrain development and emotional behavior

22 September 2017

1 reference

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GABAergic neuronal subtypes in the human frontal cortex--development and deficits in schizophrenia

22 September 2017

1 reference

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Selective alterations in glutamate and GABA receptor subunit mRNA expression in dysplastic neurons and giant cells of cortical tubers

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Altered ratios of alternatively spliced long and short gamma2 subunit mRNAs of the gamma-amino butyrate type A receptor in prefrontal cortex of schizophrenics

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

GABAA receptor subunit gene expression in human prefrontal cortex: comparison of schizophrenics and controls

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Switch in the expression of rat GABAA-receptor subtypes during postnatal development: an immunohistochemical study

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Another mechanism for creating diversity in gamma-aminobutyrate type A receptors: RNA splicing directs expression of two forms of gamma 2 phosphorylation site

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Identification of the cAMP-dependent protein kinase and protein kinase C phosphorylation sites within the major intracellular domains of the beta 1, gamma 2S, and gamma 2L subunits of the gamma-aminobutyric acid type A receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Deficiency in inhibitory cortical interneurons associates with hyperactivity in fibroblast growth factor receptor 1 mutant mice

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Abnormal laminar position and dendrite development of interneurons in the reeler forebrain.

17 June 2018

1 reference

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GABA A receptor abnormalities in Prader-Willi syndrome assessed with positron emission tomography and [11C]flumazenil

17 June 2018

1 reference

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Columnar architecture sculpted by GABA circuits in developing cat visual cortex

17 June 2018

1 reference

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Tolerance to diazepam and changes in GABA(A) receptor subunit expression in rat neocortical areas.

17 June 2018

1 reference

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In situ hybridization evidence of differential modulation by pentobarbital of GABAA receptor alpha 1- and beta 3-subunit mRNAs

17 June 2018

1 reference

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Regulation of GABAA receptor function by protein kinase C phosphorylation

17 June 2018

1 reference

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Chronic ethanol consumption differentially alters the expression of gamma-aminobutyric acidA receptor subunit mRNAs in rat cerebral cortex: competitive, quantitative reverse transcriptase-polymerase chain reaction analysis.

17 June 2018

1 reference

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The role of Robo3 in the development of cortical interneurons.

17 June 2018

1 reference

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Juvenile stress-induced alteration of maturation of the GABAA receptor alpha subunit in the rat.

20 August 2018

1 reference

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Locomotor deficiencies and aberrant development of subtype-specific GABAergic interneurons caused by an unliganded thyroid hormone receptor alpha1.

20 August 2018

1 reference

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Anomalous inhibitory circuits in cortical tubers of human tuberous sclerosis complex associated with refractory epilepsy: aberrant expression of parvalbumin and calbindin-D28k in dysplastic cortex.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Three brief epileptic seizures reduce inhibitory synaptic currents, GABA(A) currents, and GABA(A)-receptor subunits.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Altered expression of alpha3-containing GABAA receptors in the neocortex of patients with focal epilepsy.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Decreased expression of the GABAA receptor in fragile X syndrome.

20 August 2018

1 reference

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An analysis paradigm for investigating multi-locus effects in complex disease: examination of three GABA receptor subunit genes on 15q11-q13 as risk factors for autistic disorder.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Disruption of interneuron development

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Region- and age-specific deficits in gamma-aminobutyric acidergic neuron development in the telencephalon of the uPAR(-/-) mouse

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Altered expression of GABA(A) and GABA(B) receptor subunit mRNAs in the hippocampus after kindling and electrically induced status epilepticus.

20 August 2018

1 reference

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Age-dependent spontaneous hyperexcitability and impairment of GABAergic function in the hippocampus of mice lacking trkB.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Long-term effects of diazepam and phenobarbital treatment during development on GABA receptors, transporters and glutamic acid decarboxylase

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

A linkage disequilibrium map of the 1-Mb 15q12 GABA(A) receptor subunit cluster and association to autism.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Specific GABAA circuits for visual cortical plasticity.

20 August 2018

1 reference

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Regionally restricted expression of the transcription factor c‐myc intron 1 binding protein during brain development

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

The gamma 2 subunit of GABA(A) receptors is required for maintenance of receptors at mature synapses.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Effects of prenatal malnutrition on GABAA receptor α1, α3 and β2 mRNA levels

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Variations in maternal care alter GABA(A) receptor subunit expression in brain regions associated with fear.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Genetic disruption of cortical interneuron development causes region- and GABA cell type-specific deficits, epilepsy, and behavioral dysfunction.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Reciprocal alterations in pre- and postsynaptic inhibitory markers at chandelier cell inputs to pyramidal neurons in schizophrenia

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Understanding the neurotransmitter pathology of schizophrenia: selective deficits of subtypes of cortical GABAergic neurons

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Prenatal protein malnutrition reduces beta(2), beta(3) and gamma(2L) GABA(A) receptor subunit mRNAs in the adult septum.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Gene expression profiling reveals alterations of specific metabolic pathways in schizophrenia.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

The function and the expression of forebrain GABA(A) receptors change with hormonal state in the adult mouse

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Gender, estrous cycle, ovariectomy, and ovarian hormones influence the effects of diazepam on avoidance conditioning in rats.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Mice lacking the long splice variant of the gamma 2 subunit of the GABA(A) receptor are more sensitive to benzodiazepines

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Benzodiazepine-mediated regulation of alpha1, alpha2, beta1-3 and gamma2 GABA(A) receptor subunit proteins in the rat brain hippocampus and cortex.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Temporal and regional regulation of alpha1, beta2 and beta3, but not alpha2, alpha4, alpha5, alpha6, beta1 or gamma2 GABA(A) receptor subunit messenger RNAs following one-week oral flurazepam administration.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Postsynaptic clustering of major GABAA receptor subtypes requires the gamma 2 subunit and gephyrin.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Selective changes in single cell GABA(A) receptor subunit expression and function in temporal lobe epilepsy.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Pentobarbital decreases the gamma-aminobutyric acidA receptor subunit gamma-2 long/short mRNA ratio by a mechanism distinct from receptor occupation.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

Chronic treatment with diazepam or abecarnil differently affects the expression of GABAA receptor subunit mRNAs in the rat cortex.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2880553

uPAR-uPA-PAI-1 interactions and signaling: a vascular biologist's view

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20381588

12 December 2020

inferred from PubMed ID database lookup

Early loss of interneurons and delayed subunit-specific changes in GABA(A)-receptor expression in a mouse model of mesial temporal lobe epilepsy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20381588

12 December 2020

inferred from PubMed ID database lookup

Decreased glutamic acid decarboxylase67 messenger RNA expression in a subset of prefrontal cortical gamma-aminobutyric acid neurons in subjects with schizophrenia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20381588

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.NEUROSCIENCE.2010.03.066

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20381588%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20381588%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

PubMed publication ID

20381588

1 reference