(Q39886159)

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Proteasome inhibitor differentially regulates expression of the major immediate early genes of human cytomegalovirus in human central nervous system-derived cell lines

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Europe PubMed Central

PubMed publication ID

15 September 2017

Proteasome inhibitor differentially regulates expression of the major immediate early genes of human cytomegalovirus in human central nervous system-derived cell lines (English)

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Europe PubMed Central

PubMed publication ID

15 September 2017

Cytomegalovirus

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immediate early gene

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author name string

Hidetaka Sadanari

1

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Europe PubMed Central

PubMed publication ID

15 September 2017

Junji Tanaka

2

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Europe PubMed Central

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15 September 2017

Zhuan Li

3

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Europe PubMed Central

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15 September 2017

Rie Yamada

4

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15 September 2017

Keiko Matsubara

5

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15 September 2017

Tsugiya Murayama

6

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15 September 2017

publication date

6 February 2009

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Europe PubMed Central

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15 September 2017

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15 September 2017

142

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15 September 2017

1-2

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15 September 2017

68-77

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Europe PubMed Central

PubMed publication ID

15 September 2017

Neutrality of the canonical NF-kappaB-dependent pathway for human and murine cytomegalovirus transcription and replication in vitro

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Human cytomegalovirus (HCMV) UL82 gene product (pp71) relieves hDaxx-mediated repression of HCMV replication

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Opportunistic viral infections in the setting of human immunodeficiency virus

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Activation of the NF-kappaB pathway in human cytomegalovirus-infected cells is necessary for efficient transactivation of the major immediate-early promoter

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Posttranscriptional suppression of interleukin-6 production by human cytomegalovirus.

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The immediate early genes of human cytomegalovirus upregulate tumor necrosis factor-alpha gene expression

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Transcription factor ATF2 regulation by the JNK signal transduction pathway

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Selective interaction of JNK protein kinase isoforms with transcription factors

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Regulation of the transcription and replication cycle of human cytomegalovirus is insensitive to genetic elimination of the cognate NF-kappaB binding sites in the enhancer

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The 72K IE1 and 80K IE2 proteins of human cytomegalovirus independently trans-activate the c-fos, c-myc and hsp70 promoters via basal promoter elements

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Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity

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Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

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A model for reactivation of CMV from latency

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Proteasome-dependent, ubiquitin-independent degradation of Daxx by the viral pp71 protein in human cytomegalovirus-infected cells

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Modulation of interleukin 1 beta gene expression by the immediate early genes of human cytomegalovirus

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Inhibition of proteasome function leads to NF-κB-independent IL-8 expression in human hepatocytes

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Regulation of human cytomegalovirus immediate-early gene expression

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Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity

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The immediate early gene 1 product of human cytomegalovirus is sufficient for up-regulation of interleukin-8 gene expression.

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Unexpected transcriptional induction of monocyte chemoattractant protein 1 by proteasome inhibition: involvement of the c-Jun N-terminal kinase-activator protein 1 pathway

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Human cytomegalovirus persistent infection in a human central nervous system cell line: production of a variant virus with different growth characteristics

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Role of the cellular protein hDaxx in human cytomegalovirus immediate-early gene expression

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SUMO-1 modification of the major immediate-early (IE) 1 and 2 proteins of human cytomegalovirus is regulated by different mechanisms and modulates the intracellular localization of the IE1, but not IE2, protein

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The effect of cyclic AMP on expression of the major immediate-early genes and replication of human cytomegalovirus in human central nervous system cell lines

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The major immediate-early genes of human cytomegalovirus induce two novel proteins with molecular weights of 91 and 102 kilodaltons

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Inactivating a cellular intrinsic immune defense mediated by Daxx is the mechanism through which the human cytomegalovirus pp71 protein stimulates viral immediate-early gene expression

1 reference

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Proteasome inhibitor MG-132 enhances the expression of interleukin-6 in human umbilical vein endothelial cells: Involvement of MAP/ERK kinase

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ATF-2 and C/EBPalpha can form a heterodimeric DNA binding complex in vitro. Functional implications for transcriptional regulation

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Activation and regulation of human cytomegalovirus early genes

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Sodium butyrate-inducible replication of human cytomegalovirus in a human epithelial cell line

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Depolarization strongly induces human cytomegalovirus major immediate-early promoter/enhancer activity in neurons

1 reference

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Human Daxx-mediated repression of human cytomegalovirus gene expression correlates with a repressive chromatin structure around the major immediate early promoter

1 reference

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Proteasome inhibitors stimulate interleukin-8 expression via Ras and apoptosis signal-regulating kinase-dependent extracellular signal-related kinase and c-Jun N-terminal kinase activation

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The immediate early gene of human cytomegalovirus stimulates vascular smooth muscle cell proliferation in vitro and in vivo

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Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element.

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The human cytomegalovirus UL55 (gB) and UL75 (gH) glycoprotein ligands initiate the rapid activation of Sp1 and NF-kappaB during infection

1 reference

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based on heuristic

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Identifiers

10.1016/J.VIRUSRES.2009.01.010

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

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