(Q39887368)

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The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells

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Europe PubMed Central

PubMed publication ID

15 September 2017

The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

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based on heuristic

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acute myeloid leukemia

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author name string

C Flotho

1

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Europe PubMed Central

PubMed publication ID

15 September 2017

R Claus

2

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Europe PubMed Central

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15 September 2017

C Batz

3

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Europe PubMed Central

PubMed publication ID

15 September 2017

M Schneider

4

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Europe PubMed Central

PubMed publication ID

15 September 2017

I Sandrock

5

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Europe PubMed Central

PubMed publication ID

15 September 2017

S Ihde

6

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

C Plass

7

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

C M Niemeyer

8

1 reference

Europe PubMed Central

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15 September 2017

M Lübbert

9

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Europe PubMed Central

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15 September 2017

publication date

5 February 2009

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Europe PubMed Central

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15 September 2017

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Europe PubMed Central

PubMed publication ID

15 September 2017

23

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15 September 2017

6

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Europe PubMed Central

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15 September 2017

1019-1028

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Europe PubMed Central

PubMed publication ID

15 September 2017

https://scigraph.springernature.com/pub.10.1038/leu.2008.397

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Worms gang up on bacteria

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https://api.crossref.org/works/10.1038%2FLEU.2008.397

21 January 2018

Decitabine in acute myeloid leukemia

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7 January 2021

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Further analysis of trials with azacitidine in patients with myelodysplastic syndrome: studies 8421, 8921, and 9221 by the Cancer and Leukemia Group B.

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https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

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Zebularine inhibits human acute myeloid leukemia cell growth in vitro in association with p15INK4B demethylation and reexpression.

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https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

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Current status of epigenetic treatment in myelodysplastic syndromes

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https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

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Mechanism-based inhibition of C5-cytosine DNA methyltransferases by 2-H pyrimidinone 1 1Edited by J. Karn

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7 January 2021

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The fundamental role of epigenetic events in cancer

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7 January 2021

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Epigenetic therapy of cancer: past, present and future

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Reversal of p15/INK4b hypermethylation in AML1/ETO-positive and -negative myeloid leukemia cell lines.

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https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

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Susceptibility of nonpromoter CpG islands to de novo methylation in normal and neoplastic cells

1 reference

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7 January 2021

based on heuristic

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Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry

1 reference

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7 January 2021

based on heuristic

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Cell cycle effects and cellular pharmacology of 5-AZA-2?-deoxycytidine

1 reference

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7 January 2021

based on heuristic

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Epigenetic therapy of cancer with 5-aza-2'-deoxycytidine (decitabine).

1 reference

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Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial

1 reference

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7 January 2021

based on heuristic

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CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

inferred from DOI database lookup

Epigenetic modification of CCAAT/enhancer binding protein alpha expression in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhancement of antineoplastic action of 5-aza-2'-deoxycytidine by zebularine on L1210 leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

inferred from DOI database lookup

Epigenetic down-regulation of CDKN1C/p57KIP2 in pancreatic ductal neoplasms identified by gene expression profiling

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

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Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia

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https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

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MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

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https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

inferred from DOI database lookup

MEIS 1 expression is downregulated through promoter hypermethylation in AML1-ETO acute myeloid leukemias.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

inferred from DOI database lookup

Hepatocyte growth factor receptor c-MET is associated with FAS and when activated enhances drug-induced apoptosis in pediatric B acute lymphoblastic leukemia with TEL-AML1 translocation

1 reference

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7 January 2021

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ID1 and ID2 are retinoic acid responsive genes and induce a G0/G1 accumulation in acute promyelocytic leukemia cells.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

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Dlk1 in normal and abnormal hematopoiesis.

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https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

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PINCH-1 regulates the ERK-Bim pathway and contributes to apoptosis resistance in cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

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A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

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Induction of gene expression by 5-Aza-2'-deoxycytidine in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) but not epithelial cells by DNA-methylation-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

inferred from DOI database lookup

Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

inferred from DOI database lookup

Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

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Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines.

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https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

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Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

inferred from DOI database lookup

Limited gene activation in tumor and normal epithelial cells treated with the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

inferred from DOI database lookup

Preferential response of cancer cells to zebularine.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

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Preferential cytogenetic response to continuous intravenous low-dose decitabine (DAC) administration in myelodysplastic syndrome with monosomy 7

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

inferred from DOI database lookup

A comparison of low-dose cytarabine and hydroxyurea with or without all-trans retinoic acid for acute myeloid leukemia and high-risk myelodysplastic syndrome in patients not considered fit for intensive treatment

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

inferred from DOI database lookup

Activity of decitabine in patients with myelodysplastic syndrome previously treated with azacitidine

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.397

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/LEU.2008.397

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

ResearchGate publication ID

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