(Q39896057)

15 September 2017

B5, a novel pyrrole-substituted indolinone, exerts potent antitumor efficacy through G2/M cell cycle arrest (English)

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15 September 2017

Xishan Xiong

1

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15 September 2017

Yingwei Zhang

2

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15 September 2017

Xiang Gao

3

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15 September 2017

Zheyi Dong

4

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15 September 2017

Lin Li

5

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15 September 2017

Chengcheng Ji

6

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15 September 2017

Lili Fu

7

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15 September 2017

Xiaomin Luo

8

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15 September 2017

Hong Liu

9

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15 September 2017

Changlin Mei

10

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15 September 2017

13 January 2009

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Investigational New Drugs

15 September 2017

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15 September 2017

28

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15 September 2017

1

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15 September 2017

26-34

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https://scigraph.springernature.com/pub.10.1007/s10637-008-9211-7

15 September 2017

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cites work

Gefitinib ('IRESSA', ZD1839) inhibits EGF-induced invasion in prostate cancer cells by suppressing PI3 K/AKT activation.

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10637-008-9211-7

Progesterone inhibits estrogen-induced cyclin D1 and cdk4 nuclear translocation, cyclin E- and cyclin A-cdk2 kinase activation, and cell proliferation in uterine epithelial cells in mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10637-008-9211-7

Identification of substituted 3-[(4,5,6, 7-tetrahydro-1H-indol-2-yl)methylene]-1,3-dihydroindol-2-ones as growth factor receptor inhibitors for VEGF-R2 (Flk-1/KDR), FGF-R1, and PDGF-Rbeta tyrosine kinases

21 January 2018

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12 December 2020

Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle

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12 December 2020

Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors

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12 December 2020

Targeting epidermal growth factor receptor--are we missing the mark?

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12 December 2020

Recycling the Cell Cycle

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12 December 2020

Cyclin D2 activates Cdk2 in preference to Cdk4 in human breast epithelial cells

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12 December 2020

Synthesis and antiproliferative activities of indolin-2-one derivatives bearing amino acid moieties

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12 December 2020

A novel cdk2-selective inhibitor, SU9516, induces apoptosis in colon carcinoma cells

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12 December 2020

Gefitinib, a selective EGFR tyrosine kinase inhibitor, induces apoptosis through activation of Bax in human gallbladder adenocarcinoma cells

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12 December 2020

Selective anticancer drugs

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12 December 2020

Cyclin-dependent kinases as cellular targets for antiviral drugs

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12 December 2020

Design, synthesis, and evaluations of substituted 3-[(3- or 4-carboxyethylpyrrol-2-yl)methylidenyl]indolin-2-ones as inhibitors of VEGF, FGF, and PDGF receptor tyrosine kinases

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12 December 2020

Activated Src and Ras induce gefitinib resistance by activation of signaling pathways downstream of epidermal growth factor receptor in human gallbladder adenocarcinoma cells

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12 December 2020

EGF receptor modifies cellular responses to hyaluronan in glioblastoma cell lines

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12 December 2020

SU9516: biochemical analysis of cdk inhibition and crystal structure in complex with cdk2

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12 December 2020

Involvement of p27(kip1) and cyclin D3 in the regulation of cdk2 activity during skeletal muscle differentiation

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12 December 2020

Cyclin-dependent kinases at the G1-S transition of the mammalian cell cycle

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12 December 2020

Design, synthesis, antitumor evaluations and molecular modeling studies of novel 3,5-substituted indolin-2-one derivatives

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12 December 2020

Tyrosine kinase inhibitors. 11. Soluble analogues of pyrrolo- and pyrazoloquinazolines as epidermal growth factor receptor inhibitors: synthesis, biological evaluation, and modeling of the mode of binding

1 reference

12 December 2020

HIV-1 Vpr activates cell cycle inhibitor p21/Waf1/Cip1: a potential mechanism of G2/M cell cycle arrest

1 reference

12 December 2020

Synthesis and biological evaluations of 3-substituted indolin-2-ones: a novel class of tyrosine kinase inhibitors that exhibit selectivity toward particular receptor tyrosine kinases

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12 December 2020

DNA sequence selective adenine alkylation, mechanism of adduct repair, and in vivo antitumor activity of the novel achiral seco-amino-cyclopropylbenz[e]indolone analogue of duocarmycin AS-I-145.

1 reference

12 December 2020

Reversible tyrosine phosphorylation of cdc2: dephosphorylation accompanies activation during entry into mitosis

1 reference

12 December 2020

Cancer statistics, 2007

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12 December 2020

Recycling the cell cycle: cyclins revisited

1 reference

12 December 2020

10.1007/S10637-008-9211-7

Identifiers

DOI

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15 September 2017

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