(Q39900881)

15 September 2017

Leptin utilizes Jun N-terminal kinases to stimulate the invasion of MCF-7 breast cancer cells (English)

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15 September 2017

Vanity McMurtry

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15 September 2017

Ann-Marie Simeone

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2

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15 September 2017

René Nieves-Alicea

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3

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15 September 2017

Ana M Tari

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4

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15 September 2017

27 December 2008

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Clinical & Experimental Metastasis

15 September 2017

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15 September 2017

26

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15 September 2017

197-204

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15 September 2017

3

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https://scigraph.springernature.com/pub.10.1007/s10585-008-9231-x

15 September 2017

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cites work

Leptin--a growth factor in normal and malignant breast cells and for normal mammary gland development

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10585-008-9231-X

Production of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human breast carcinomas.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10585-008-9231-X

Effects of leptin on human breast cancer cell lines in relationship to estrogen receptor and HER2 status

21 January 2018

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12 December 2020

Leptin-induced growth of human ZR-75-1 breast cancer cells is associated with up-regulation of cyclin D1 and c-Myc and down-regulation of tumor suppressor p53 and p21WAF1/CIP1.

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12 December 2020

Leptin Enhances, via AP-1, Expression of Aromatase in the MCF-7 Cell Line

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12 December 2020

Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells

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12 December 2020

Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

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12 December 2020

Radiommunological measurement of leptin in plasma of obese and diabetic human subjects

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12 December 2020

Leptin receptor-deficient MMTV-TGF-alpha/Lepr(db)Lepr(db) female mice do not develop oncogene-induced mammary tumors

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12 December 2020

Positional cloning of the mouse obese gene and its human homologue

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12 December 2020

Sequential activation and production of matrix metalloproteinase-2 during breast cancer progression

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12 December 2020

Weight change and risk of postmenopausal breast cancer (United States).

1 reference

12 December 2020

Associations between energy balance and body mass index and risk of breast carcinoma in women from diverse racial and ethnic backgrounds in the U.S.

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12 December 2020

Sequential production and activation of matrix-metalloproteinase-9 (MMP-9) with breast cancer progression

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12 December 2020

Effect of obesity on presentation of breast cancer.

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12 December 2020

Evidences that leptin up-regulates E-cadherin expression in breast cancer: effects on tumor growth and progression.

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12 December 2020

Role of matrix metalloproteinase-2 in ethanol-induced invasion by breast cancer cells

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12 December 2020

Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways

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12 December 2020

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12 December 2020

Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer

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12 December 2020

Expression of pp60c-src protein kinase in adult and fetal human tissue: high activities in some sarcomas and mammary carcinomas.

1 reference

12 December 2020

Leptin signaling promotes the growth of mammary tumors and increases the expression of vascular endothelial growth factor (VEGF) and its receptor type two (VEGF-R2)

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12 December 2020

High expression of leptin receptor mRNA in breast cancer tissue predicts poor prognosis for patients with high, but not low, serum leptin levels

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12 December 2020

C-SRC tyrosine kinase activity is associated with tumor colonization in bone and lung in an animal model of human breast cancer metastasis

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12 December 2020

Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas

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12 December 2020

Analysis of pp60c-src protein kinase activity in human tumor cell lines and tissues

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12 December 2020

Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways

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12 December 2020

Inhibition of protein kinase c-Src reduces the incidence of breast cancer metastases and increases survival in mice: implications for therapy

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12 December 2020

Hypoxia-induced bFGF gene expression is mediated through the JNK signal transduction pathway.

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12 December 2020

The effect of leptin on mouse trophoblast cell invasion.

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12 December 2020

Leptin stimulates proliferation and inhibits apoptosis in Barrett's esophageal adenocarcinoma cells by cyclooxygenase-2-dependent, prostaglandin-E2-mediated transactivation of the epidermal growth factor receptor and c-Jun NH2-terminal kinase activa

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12 December 2020

leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3

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12 December 2020

Endothelial cells and normal breast epithelial cells enhance invasion of breast carcinoma cells by CXCR-4-dependent up-regulation of urokinase-type plasminogen activator receptor (uPAR, CD87) expression.

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12 December 2020

Leptin interferes with the effects of the antiestrogen ICI 182,780 in MCF-7 breast cancer cells.

1 reference

12 December 2020

Increased expression of leptin and the leptin receptor as a marker of breast cancer progression: possible role of obesity-related stimuli.

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12 December 2020

SRC kinase and mitogen-activated protein kinases in the progression from normal to malignant endometrium

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12 December 2020

Messenger RNA expression of leptin and leptin receptors and their prognostic value in 322 human primary breast cancers

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12 December 2020

Leptin induces, via ERK1/ERK2 signal, functional activation of estrogen receptor alpha in MCF-7 cells.

1 reference

12 December 2020

Relation between steroid receptor status and body weight in breast cancer patients.

1 reference

12 December 2020

Body weight and prognostic indicators in breast cancer. Modifying effect of estrogen receptors

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12 December 2020

Upregulation of survivin by leptin/STAT3 signaling in MCF-7 cells

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12 December 2020

Leptin promotes invasiveness of murine renal cancer cells via extracellular signal-regulated kinases and rho dependent pathway

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12 December 2020

Obesity, body size, and risk of postmenopausal breast cancer: the Women's Health Initiative (United States).

1 reference

12 December 2020

Characterization of protein tyrosine kinases from human breast cancer: involvement of the c-src oncogene product.

1 reference

12 December 2020

Body mass index, height, and postmenopausal breast cancer mortality in a prospective cohort of US women

1 reference

12 December 2020

Leptin: a proliferative factor for breast cancer? Study on human ductal carcinoma

1 reference

12 December 2020

Evidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fasting

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12 December 2020

Estrogen receptor alpha positive breast tumors and breast cancer cell lines share similarities in their transcriptome data structures.

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12 December 2020

Molecular mechanisms involved in the growth stimulation of breast cancer cells by leptin

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12 December 2020

The anti-apoptotic and growth stimulatory actions of leptin in human colon cancer cells involves activation of JNK mitogen activated protein kinase, JAK2 and PI3 kinase/Akt

1 reference

12 December 2020

Leptin modulates extracellular matrix molecules and metalloproteinases: possible implications for trophoblast invasion

1 reference

12 December 2020

Prostate cancer cell-adipocyte interaction: leptin mediates androgen-independent prostate cancer cell proliferation through c-Jun NH2-terminal kinase

1 reference

12 December 2020

10.1007/S10585-008-9231-X

Identifiers

DOI

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15 September 2017

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