(Q39931950)

15 September 2017

1 reference

title

L-Asparaginase: A Review (English)

1 reference

https://api.crossref.org/works/10.1002/9780470122846.CH3

8 February 2023

author name string

J. C. Wriston

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A4583638

8 February 2023

T. O. Yellin

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A4583638

8 February 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=4583638

8 February 2023

publication date

1 January 1973

1 reference

full work available at URL

15 September 2017

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2F9780470122846.ch3

1 reference

https://api.crossref.org/works/10.1002/9780470122846.CH3

https://onlinelibrary.wiley.com/doi/full/10.1002/9780470122846.ch3

8 February 2023

1 reference

https://api.crossref.org/works/10.1002/9780470122846.CH3

Advances in Enzymology and Related Areas of Molecular Biology

8 February 2023

published in

1 reference

15 September 2017

volume

39

1 reference

15 September 2017

page(s)

185-248

1 reference

L-Asparaginase and L-Asparagine Metabolism

15 September 2017

cites work

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Evidence that the L-asparaginase of guinea pig serum is responsible for its antilymphoma effects. I. Properties of the L-asparaginase of guinea pig serum in relation to those of the antilymphoma substance

8 February 2023

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Evidence that the L-asparaginase of guinea pig serum is responsible for its antilymphoma effects. II. Lymphoma 6C3HED cells cultured in a medium devoid of L-asparagine lose their susceptibility to the effects of guinea pig serum in vivo

8 February 2023

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The regulation of L-asparaginase activity in rats and mice. Effects of normal and malignant growth, of sex and of dietary changes

8 February 2023

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The Developmental Formation of Asparaginase in Liver and its Distribution in Rat Tissues

8 February 2023

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Enzymes in cancer. Asparaginase from chicken liver

8 February 2023

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Manometric determination of L-aspartic acid and L-asparagine

8 February 2023

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The action of mammalian liver enzyme preparations on asparagine and asparagine derivatives

8 February 2023

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Escherichia coli L-asparaginase. Catalytic activity and subunit nature

8 February 2023

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Purification and Properties of Guinea Pig Serum Asparaginase*

8 February 2023

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Purification and properties of asparaginase from escherichia coli B.

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Isolation and properties of L-asparaginases from Escherichia coli.

8 February 2023

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Purification and Properties of l -Asparaginase from Serratia marcescens

8 February 2023

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Physical properties and subunit structure of l-asparaginase isolated from Erwinia carotovora

8 February 2023

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L-Asparaginase form Proteus vulgaris. Purification, crystallization, and enzymic properties

8 February 2023

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Purification and properties of an l-asparaginase from Fusarium tricinctum

8 February 2023

41

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Purification and properties of Bacillus coagulansl-asparaginase

8 February 2023

43

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L-asparaginases from Mycobacterium tuberculosis strains H37Rv and H37Ra

8 February 2023

44

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Hydrolysis of amides by extracts from Mycobacteria

8 February 2023

49

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The asparagine deamidase of Bacillus coagulans and Bacillus stearothermophilus

8 February 2023

50

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Stereospecific asparaginases in smooth Brucella abortus, strain 19

8 February 2023

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The action of Pseudomonas fluorescens extracts on asparagine and asparagine derivatives

8 February 2023

52

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L-Asparaginase EC-2 from Escherichia coli. Some substrate specificity characteristics

8 February 2023

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8 February 2023

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37

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Two L-asparaginases from E. coli and their action against tumors

8 February 2023

61

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Two L-asparaginases from Escherichia coli B. Their separation, purification, and antitumor activity

8 February 2023

62

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Immunosuppression by L-Asparaginase

8 February 2023

63

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New procedures for purification of L-asparaginase with high yield from Escherichia coli

8 February 2023

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Biochimica et Biophysica Acta

8 February 2023

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PURIFICATION AND PROPERTIES OF GLUTAMINASE AND ASPARAGINASE FROM A PSEUDOMONAD. I. PURIFICATION AND PHYSICAL CHEMICAL PROPERTIES

8 February 2023

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8 February 2023

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The substrate specificity of L-asparaginase from Alcaligenes eutrophus

8 February 2023

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Automated determination of bacterial asparaginase and glutaminase

8 February 2023

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L-asparaginase activity in plasma and other biological fluids

8 February 2023

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AN ENZYMIC MICROMETHOD FOR DETERMINATION OF GLUTAMINE AND ASPARAGINE IN BLOOD

8 February 2023

81

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Factors which may influence the effectiveness of L-asparaginases as tumor inhibitors

8 February 2023

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The effect of animal sera and bovine serum albumin on l-asparaginase determination in vitro

8 February 2023

84

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l-Asparaginase from Erwinia carotovora

8 February 2023

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Subunit structure of l-asparaginase from Escherichia coli B

8 February 2023

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L-Asparaginase A fromEscherichia coli.The Molecular Weight of the Subunit and the Demonstration of an Intramolecular Disulfide Bridge

8 February 2023

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Multiple forms of L-asparaginase

8 February 2023

93

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Yeast phosphoglyceric acid mutase-modifying enzyme

8 February 2023

95

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Multiple forms and subunits of yeast hexokinase

8 February 2023

96

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[Crystallographic data of a monocline modification of L-Asparaginase A from Escherichia coli]

8 February 2023

98

1 reference

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Crystallographic Evidence for the Tetrameric Subunit Structure of l-Asparaginase from Escherichia coli

8 February 2023

99

1 reference

https://api.crossref.org/works/10.1002/9780470122846.CH3

8 February 2023

Conformation of proteins

101

1 reference

https://api.crossref.org/works/10.1002/9780470122846.CH3

Partial purification and antilymphoma activity of Serratia marcescensL-asparaginase

8 February 2023

106

1 reference

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Inhibition of HeLa cell cultures by preparations of Escherichia coli L-asparaginase

8 February 2023

107

1 reference

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β-Cyanoalanine as a substrate for asparaginase stoichiometry, kinetics, and inhibition

8 February 2023

108

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Hybridization of native and chemically modified enzymes. I. Development of a general method and its application to the study of the subunit structure of aldolase

8 February 2023

110

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A comparison of L-asparaginase from Erwinia aroideae and from Escherichia coli: biochemical and biological properties

8 February 2023

111

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Partially deaminated L-asparaginase

8 February 2023

112

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Stereospecificity of the catalytic reaction of L-asparaginase

8 February 2023

115

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Stereospecific features of the conformative response of L-asparaginase

8 February 2023

116

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Glutaminase activity of L-asparagine amidohydrolase

8 February 2023

117

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5-Diazo-4-Oxo-L-Norvaline: Reactive Asparagine Analog with Biological Specificity

8 February 2023

118

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The kinetics of enzyme-catalyzed reactions with two or more substrates or products

8 February 2023

120

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States of tyrosine residues in l-asparaginase: The existence of tyrosine residues having abnormally low pK in l-asparaginase

8 February 2023

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8 February 2023

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Insolubilization of L-asparaginase by covalent attachment to nylon tubing

8 February 2023

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Glutaminase induced prolonged regression of established Ehrlich carcinoma

8 February 2023

129

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Suppression of murine leukemias by L-asparaginase. Incidence of sensitivity among leukemias of various types: comparative inhibitory activities of guinea pig serum L-asparaginase and Escherichia coli L-asparaginase

8 February 2023

130

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L-asparaginase: therapeutic and toxic effects in patients with neoplastic disease

8 February 2023

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8 February 2023

134

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E. coli L-asparaginase in the treatment of leukemia and solid tumors in 131 children

8 February 2023

135

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Clinical results of treatment with E. coli L-asparaginase in adults with leukemia, lymphoma, and solid tumors

8 February 2023

136

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Toxicity of E. coli L-asparaginase in man

8 February 2023

137

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Regression of transplanted lymphomas induced in vivo by means of normal guinea pig serum. I. Course of transplanted cancers of various kinds in mice and rats given guinea pig serum, horse serum, or rabbit serum

8 February 2023

140

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Effects of guinea pig serum on 6C3HED and AKRL1 lymphoma cells implanted in various hosts

8 February 2023

141

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Electrophoretical mobility of human lymphocytes in the presence of E. colil-asparaginase

8 February 2023

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8 February 2023

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Effects of arsenic-azoproteins on mouse lymphoma cells in vivo; with observations on the effects of other anti-lymphoma agents, and on the susceptibility to these effects of lymphoma cells of various types

8 February 2023

144

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Antagonism of purified asparaginase from guinea pig serum toward lymphoma

8 February 2023

145

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TUMOR INHIBITORY EFFECT OF L-ASPARAGINASE FROM ESCHERICHIA COLI

8 February 2023

146

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A METABOLIC DIFFERENCE BETWEEN TWO LINES OF LYMPHOMA 6C3HED CELLS IN RELATION TO ASPARAGINE

8 February 2023

147

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8 February 2023

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8 February 2023

Cancer chemotherapy

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L-Asparaginase in Treatment of Acute Leukaemia and Lymphosarcoma

8 February 2023

151

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Duration and severity of fatty metamorphosis of the liver following L-asparaginase therapy

8 February 2023

152

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8 February 2023

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8 February 2023

154

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Jaffe

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Hepatic Lipidosis Associated with l-Asparaginase Treatment

8 February 2023

157

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L-asparaginase and pancreatitis

8 February 2023

158

1 reference

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Effect of L-asparaginase on carbohydrate metabolism

8 February 2023

159

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Diabetogenic Effect ofl-Asparaginase

8 February 2023

160

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Effect of L-Asparaginase on the Ability of Normal Mouse Bone Marrow to form Soft Agar Colonies

8 February 2023

161

1 reference

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L -Asparaginase: Inhibition of Early Mitosis in Regenerating Rat Liver

8 February 2023

162

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8 February 2023

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Schwartz

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8 February 2023

164

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L-Asparaginase: Toxicity to Normal and Leukemic Human Lymphocytes

8 February 2023

165

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8 February 2023

166

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L-Glutaminase: Suppression of Lymphocyte Blastogenic Responses in vitro

8 February 2023

168

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Effects of L-Asparaginase on Lymphocyte-Target Cell Reactions in vitro

8 February 2023

169

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Immunosuppression by L-Asparaginase

8 February 2023

170

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Immunosuppression by L-Asparaginase

8 February 2023

171

1 reference

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Effect of L-Asparaginase on Germinal Centre Haemolysin

8 February 2023

172

1 reference

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L-Asparaginase Induced Immunosuppression: Inhibition of Bone Marrow Derived Antibody Precursor Cells

8 February 2023

174

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8 February 2023

175

30

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Ohno

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8 February 2023

L-asparaginase

176

1 reference

https://api.crossref.org/works/10.1002/9780470122846.CH3

Inhibition of primary antibody response by E. coli asparaginase

8 February 2023

178

1 reference

https://api.crossref.org/works/10.1002/9780470122846.CH3

Immunosuppressive action of L-asparaginase

8 February 2023

179

1 reference

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L-Asparaginase-Induced Immunosuppression: Effects on Antibody-Forming Cells and Serum Titers

8 February 2023

180

1 reference

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8 February 2023

183

1 reference

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8 February 2023

184

31

114

Miura

1971

1 reference

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[Immunosuppressive effect of L-asparaginase in the graft-versus-host reaction]

8 February 2023

185

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8 February 2023

186

30

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Miura

1970

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8 February 2023

187

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8 February 2023

191

30

2665

Brambilla

1970

1 reference

https://api.crossref.org/works/10.1002/9780470122846.CH3

L-asparaginase and metastasis

8 February 2023

192

1 reference

https://api.crossref.org/works/10.1002/9780470122846.CH3

Enhancement of Metastases by L-Asparaginase in a Mouse Tumour System

8 February 2023

194

1 reference

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8 February 2023

197

26

2213

Roberts

1966

1 reference

https://api.crossref.org/works/10.1002/9780470122846.CH3

A new L-asparaginase with antitumour activity?

8 February 2023

199

1 reference

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Immunological responses to L-asparaginase

8 February 2023

200

1 reference

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8 February 2023

202

29

183

Miller

1969

1 reference

https://api.crossref.org/works/10.1002/9780470122846.CH3

MECHANISM OF LACTATE DEHYDROGENASE (LDH) ELEVATION IN VIRUS-INFECTED HOSTS.

8 February 2023

203

1 reference

https://api.crossref.org/works/10.1002/9780470122846.CH3

Role of the LDH-elevating Virus in Leukaemia Therapy by Asparaginase

8 February 2023

205

1 reference

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Isolation and characterization of plasma membranes from an L-asparaginase-sensitive strain of leukemia cells.

8 February 2023

206

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A Comparison of Concurrent and Delayed Tests for Antitumor Activity of L-Asparaginase

8 February 2023

208

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Inhibition of Glycoprotein Synthesis in L5178Y Mouse Leukaemic Cells by L-Asparaginase in vitro

8 February 2023

211

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Controlled deamidation of peptides and proteins: an experimental hazard and a possible biological timer

8 February 2023

213

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Studies on the mechanism of tumor inhibition by L-asparaginase. Effects of the enzyme on asparagine levels in the blood, normal tissues, and 6C3HED lymphomas of mice: differences in asparagine formation and utilization in asparaginase-sensitive and

8 February 2023

215

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Differences in the production of l-asparagine in asparaginase-sensitive and resistant lymphoma cells

8 February 2023

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Changes in ribonuclease activities in P1798 lymphosarcoma after asparaginase treatment

8 February 2023

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L5178Y asparagine-dependent cells and independent clonal sublines. Toxicity of 5-diazo-4-oxo-L-norvaline

8 February 2023

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Antineoplastic activity of highly purified bacterial glutaminases

8 February 2023

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L-asparaginase and complement

8 February 2023

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L-asparaginase induced alteration of amethopterin (methotrexate) activity in mouse leukemia L5178Y

8 February 2023

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Dual requirement of Walker carcinosarcoma 256 in vitro for asparagine and glutamine

8 February 2023

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8 February 2023

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Asparagine synthetase activity of mouse leukemias

8 February 2023

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Asparagine synthetase in asparaginase resistant and susceptible mouse lymphomas

8 February 2023

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Asparagine synthetase in normal and malignant tissues; correlation with tumor sensitivity to asparaginase

8 February 2023

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Nutritional requirements of human leukemic cells. Asparagine requirements and the effect of L-asparaginase

8 February 2023

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Enzymatic cleavage of glycopeptides

8 February 2023

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l-Asparaginase resistance in human leukemia—Asparagine synthetase

8 February 2023

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Guinea pig asparagine synthetase

8 February 2023

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Asparaginyl-tRNA and Resistance of Murine Leukaemias to L-Asparaginase

8 February 2023

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Inhibitory Effect of Guinea Pig Serum on a Number of New Leukæmias in Mice

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Peptidoasparaginase. An enzyme for deamidation of COOH-terminal peptide-bound asparagine

8 February 2023

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Alterations in protein and nucleic acid metabolism of lymphoma 6C3HED-og cells in mice given guinea pig serum

8 February 2023

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IN VITRO EFFECTS OF GUINEA PIG SERUM ON THE JENSEN, JA-1 AND JA-2 SARCOMAS

8 February 2023

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METABOLIC CONTROLS IN CULTURED MAMMALIAN CELLS.

8 February 2023

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Response of Intracerebral Gardner Lymphoma to Guinea Pig L-Asparaginase and Escherichia coli L-Asparaginase

8 February 2023

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8 February 2023

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Serine requirement in leukemic and normal blood cells

8 February 2023

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Gamma aminobutyramide: inhibition of protein synthesis in enrlich ascites carcinoma cell suspensions

8 February 2023

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Synthesis of compounds with potential central nervous system stimulant activity. II. 5-Spiro-substituted 2-amino-2-oxazolines

8 February 2023

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Change in Ribonuclease Concentrations in L-Asparaginase-treated Lymphosarcomata

8 February 2023

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On the regulation of asparaginase synthesis in Pseudomonas boreopolis 526

8 February 2023

264

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L-Asparaginase from the BCG Strain of Mycobacterium bovis. I. Purification and In Vitro Immunosuppressive Properties

8 February 2023

265

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Purification and properties of isozymes of glutaminase from Pseudomonas aeruginosa.

8 February 2023

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In vitro Blastogenesis inhibited by Erwinia carotovora L-Asparaginase

8 February 2023

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8 February 2023

Identifiers

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=4583638

8 February 2023

1 reference