(Q39933026)

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Age-Related Changes in D-Aspartate Oxidase Promoter Methylation Control Extracellular D-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging.

scientific article published on March 2016

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26961959%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Age-Related Changes in D-Aspartate Oxidase Promoter Methylation Control Extracellular D-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging (English)

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10 March 2020

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7

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10 March 2020

Francesco Errico

2

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10 March 2020

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10 March 2020

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10 March 2020

Roberta Imperatore

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10 March 2020

Ornella Affinito

13

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10 March 2020

Sara Migliarini

14

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10 March 2020

Giacomo Maddaloni

15

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10 March 2020

Massimo Pasqualetti

17

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10 March 2020

Loredano Pollegioni

18

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10 March 2020

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Daniela Punzo

1

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10 March 2020

Luigia Cristino

3

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10 March 2020

Simona Keller

5

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10 March 2020

Carmela Belardo

6

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10 March 2020

Vito De Novellis

12

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10 March 2020

Maria Josè Sisalli

16

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10 March 2020

Sabatino Maione

19

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10 March 2020

Lorenzo Chiariotti

20

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10 March 2020

Alessandro Usiello

21

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10 March 2020

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1 March 2016

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10 March 2020

Journal of Neuroscience

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10 March 2020

36

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10 March 2020

3064-3078

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10 March 2020

10

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10 March 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6601755/fullTextXML

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inferred from PubMed Central ID database lookup

Purification of beef kidney d-aspartate oxidase overexpressed in Escherichia coli and characterization of its redox potentials and oxidative activity towards agonists and antagonists of excitatory amino acid receptors

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12 December 2020

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D-aspartate disposition in neuronal and endocrine tissues: ontogeny, biosynthesis and release

1 reference

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12 December 2020

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Characterization of electrically evoked [3H]-D-aspartate release from hippocampal slices.

1 reference

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12 December 2020

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D-Aspartate is stored in secretory granules and released through a Ca(2+)-dependent pathway in a subset of rat pheochromocytoma PC12 cells

1 reference

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12 December 2020

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Engineering the substrate specificity of D-amino-acid oxidase.

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12 December 2020

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Lipofuscin: mechanisms of age-related accumulation and influence on cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/26961959

12 December 2020

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Cellular and subcellular distribution of D-aspartate oxidase in human and rat brain

1 reference

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12 December 2020

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Uptake and release of D- and L-aspartate by rat brain slices

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Role of CpG islands in the up-regulation of NMDA receptor NR2B gene expression following chronic ethanol treatment of cultured cortical neurons of mice

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D-serine efficacy as add-on pharmacotherapy to risperidone and olanzapine for treatment-refractory schizophrenia

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D-alanine added to antipsychotics for the treatment of schizophrenia

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Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study

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12 December 2020

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A physiological mechanism to regulate D-aspartic acid and NMDA levels in mammals revealed by D-aspartate oxidase deficient mice

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12 December 2020

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D-aspartate regulates melanocortin formation and function: behavioral alterations in D-aspartate oxidase-deficient mice

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Metabolism of amino-acids: Deamination of amino-acids

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12 December 2020

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Brain lipopigment accumulation in normal and pathological aging

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Mechanisms of glutamate release elicited in rat cerebrocortical nerve endings by 'pathologically' elevated extraterminal K+ concentrations.

1 reference

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12 December 2020

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Increased levels of d-aspartate in the hippocampus enhance LTP but do not facilitate cognitive flexibility

1 reference

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12 December 2020

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Studies on the cyclophorase system; D-aspartic oxidase.

1 reference

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12 December 2020

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Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation.

1 reference

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12 December 2020

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NMDA receptor activity regulates transcription of antioxidant pathways

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12 December 2020

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D-aspartate prevents corticostriatal long-term depression and attenuates schizophrenia-like symptoms induced by amphetamine and MK-801.

1 reference

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Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease

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12 December 2020

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D-aspartate oxidase, a peroxisomal enzyme in liver of rat and man

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12 December 2020

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Persistent increase of D-aspartate in D-aspartate oxidase mutant mice induces a precocious hippocampal age-dependent synaptic plasticity and spatial memory decay.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26961959

12 December 2020

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Increased D-aspartate brain content rescues hippocampal age-related synaptic plasticity deterioration of mice.

1 reference

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12 December 2020

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High dose D-serine in the treatment of schizophrenia

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12 December 2020

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Thyroid hormones and D-aspartic acid, D-aspartate oxidase, D-aspartate racemase, H2O2, and ROS in rats and mice

1 reference

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12 December 2020

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Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

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12 December 2020

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D-Aspartic acid is a novel endogenous neurotransmitter.

1 reference

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12 December 2020

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Higher free D-aspartate and N-methyl-D-aspartate levels prevent striatal depotentiation and anticipate L-DOPA-induced dyskinesia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26961959

12 December 2020

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New insights on the role of free D-aspartate in the mammalian brain

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Lack of brain serotonin affects postnatal development and serotonergic neuronal circuitry formation.

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12 December 2020

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A thermostable L-aspartate oxidase: a new tool for biotechnological applications

1 reference

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Developmental changes in free D-aspartic acid in the chicken embryo and in the neonatal rat.

1 reference

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Decreased levels of D-aspartate and NMDA in the prefrontal cortex and striatum of patients with schizophrenia.

1 reference

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1 reference

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1 reference

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based on heuristic

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1 reference

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12 December 2020

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Free D-aspartate regulates neuronal dendritic morphology, synaptic plasticity, gray matter volume and brain activity in mammals

1 reference

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1 reference

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A role for D-aspartate oxidase in schizophrenia and in schizophrenia-related symptoms induced by phencyclidine in mice

1 reference

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12 December 2020

based on heuristic

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Characterization of the enzymatic and structural properties of human D-aspartate oxidase and comparison with those of the rat and mouse enzymes

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

d-Aspartate oxidase influences glutamatergic system homeostasis in mammalian brain.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D-Aspartate: An endogenous NMDA receptor agonist enriched in the developing brain with potential involvement in schizophrenia.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in D-aspartic acid and D-glutamic acid levels in the tissues and physiological fluids of mice with various D-aspartate oxidase activities

1 reference

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12 December 2020

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1 reference

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12 December 2020

based on heuristic

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Identification of Novel D-Aspartate Oxidase Inhibitors by in Silico Screening and Their Functional and Structural Characterization in Vitro.

1 reference

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based on heuristic

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Persistent elevation of D-Aspartate enhances NMDA receptor-mediated responses in mouse substantia nigra pars compacta dopamine neurons.

1 reference

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based on heuristic

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1 reference

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12 December 2020

based on heuristic

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1 reference

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based on heuristic

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Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex

1 reference

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12 December 2020

based on heuristic

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1 reference

https://pubmed.ncbi.nlm.nih.gov/26961959

12 December 2020

based on heuristic

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Further study on the specificity of D-amino acid oxidase and D-aspartate oxidase and time course for complete oxidation of D-amino acids

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic development and postnatal changes in free D-aspartate and D-serine in the human prefrontal cortex.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance

1 reference

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12 December 2020

based on heuristic

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Structural and functional characterization of the human brain D-aspartate oxidase

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular biology of mammalian plasma membrane amino acid transporters

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Emergence of D-aspartic acid in the differentiating neurons of the rat central nervous system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26961959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D-serine added to antipsychotics for the treatment of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/26961959

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.3881-15.2016

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26961959%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

Europe PubMed Central

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10 March 2020

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26961959%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

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