(Q39938165)

15 September 2017

title

Influence of humanized anti-IL-6R antibody, tocilizumab on the activity of soluble gp130, natural inhibitor of IL-6 signaling (English)

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15 September 2017

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Misato Hashizume

1

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15 September 2017

Masahiko Mihara

series ordinal

2

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15 September 2017

language of work or name

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20 September 2008

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Rheumatology International

15 September 2017

published in

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15 September 2017

volume

29

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15 September 2017

issue

4

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15 September 2017

page(s)

397-401

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https://scigraph.springernature.com/pub.10.1007/s00296-008-0703-8

15 September 2017

exact match

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cites work

IL-6 trans-signaling: the heat is on.

1 reference

12 December 2020

Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130

1 reference

12 December 2020

Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial.

1 reference

12 December 2020

Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab

1 reference

12 December 2020

Structural and functional studies on the human interleukin-6 receptor. Binding, cross-linking, internalization, and degradation of interleukin-6 by fibroblasts transfected with human interleukin-6-receptor cDNA.

1 reference

12 December 2020

Recombinant soluble human interleukin-6 receptor. Expression in Escherichia coli, renaturation and purification

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12 December 2020

Receptors for B cell stimulatory factor 2. Quantitation, specificity, distribution, and regulation of their expression

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12 December 2020

Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family

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12 December 2020

Molecular cloning and expression of an IL-6 signal transducer, gp130

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12 December 2020

Humanized antibody to human interleukin-6 receptor inhibits the development of collagen arthritis in cynomolgus monkeys

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12 December 2020

Soluble IL-6 receptor potentiates the antagonistic activity of soluble gp130 on IL-6 responses.

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12 December 2020

Therapeutic efficacy of humanized recombinant anti-interleukin-6 receptor antibody in children with systemic-onset juvenile idiopathic arthritis

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12 December 2020

A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease

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12 December 2020

Improvement in Castleman's disease by humanized anti-interleukin-6 receptor antibody therapy.

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12 December 2020

10.1007/S00296-008-0703-8

Identifiers

DOI

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15 September 2017

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