(Q39944513)

English

Cell surface delivery and structural re-organization by pharmacological chaperones of an oligomerization-defective alpha(1b)-adrenoceptor mutant demonstrates membrane targeting of GPCR oligomers

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Cell surface delivery and structural re-organization by pharmacological chaperones of an oligomerization-defective alpha(1b)-adrenoceptor mutant demonstrates membrane targeting of GPCR oligomers (English)

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

G protein-coupled receptor

0 references

molecular chaperones

0 references

1 reference

based on heuristic

inferred from title

author name string

Meritxell Canals

1

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Juan F Lopez-Gimenez

2

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Graeme Milligan

3

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

language of work or name

0 references

publication date

1 January 2009

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Biochemical Journal

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

417

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

1

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

161-172

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

copyright license

Creative Commons Attribution-NonCommercial 2.5 Generic

25 July 2019

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

The alpha1b-adrenoceptor exists as a higher-order oligomer: effective oligomerization is required for receptor maturation, surface delivery, and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605960

22 September 2017

G protein-coupled receptor dimerisation: molecular basis and relevance to function

1 reference

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Dimerization of CXCR4 in living malignant cells: control of cell migration by a synthetic peptide that reduces homologous CXCR4 interactions

1 reference

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Structure of the rhodopsin dimer: a working model for G-protein-coupled receptors

1 reference

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Protein folding as posttranslational regulation: evolution of a mechanism for controlled plasma membrane expression of a G protein-coupled receptor

1 reference

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Crosstalk in G protein-coupled receptors: changes at the transmembrane homodimer interface determine activation

1 reference

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The CXCR1 and CXCR2 receptors form constitutive homo- and heterodimers selectively and with equal apparent affinities

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A point mutation in the human melanin concentrating hormone receptor 1 reveals an important domain for cellular trafficking

1 reference

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Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation

1 reference

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Heterodimerization of mu- and delta-opioid receptors occurs at the cell surface only and requires receptor-G protein interactions.

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Pharmacologic rescue of conformationally-defective proteins: implications for the treatment of human disease

1 reference

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Pharmacological chaperones: potential treatment for conformational diseases.

1 reference

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G protein-coupled receptor dimerization: function and ligand pharmacology

1 reference

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Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting

1 reference

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Identification of amino acid residues crucial for chemokine receptor dimerization.

1 reference

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22 September 2017

Roles of G-protein-coupled receptor dimerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605960

22 September 2017

Pharmacological chaperones: a new twist on receptor folding.

1 reference

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A trafficking checkpoint controls GABA(B) receptor heterodimerization

1 reference

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Export from the endoplasmic reticulum represents the limiting step in the maturation and cell surface expression of the human delta opioid receptor

1 reference

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Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants

1 reference

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GABAB receptors - the first 7TM heterodimers.

1 reference

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22 September 2017

Binding-, intracellular transport-, and biosynthesis-defective mutants of vasopressin type 2 receptor in patients with X-linked nephrogenic diabetes insipidus

1 reference

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Widespread distribution of Gq alpha/G11 alpha detected immunologically by an antipeptide antiserum directed against the predicted C-terminal decapeptide.

1 reference

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Pharmacologic chaperones as a potential treatment for X-linked nephrogenic diabetes insipidus

1 reference

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Intracellular entrapment of wild-type TSH receptor by oligomerization with mutants linked to dominant TSH resistance.

1 reference

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Multiple interactions between transmembrane helices generate the oligomeric alpha1b-adrenoceptor.

1 reference

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Human loss-of-function gonadotropin-releasing hormone receptor mutants retain wild-type receptors in the endoplasmic reticulum: molecular basis of the dominant-negative effect

1 reference

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C5a receptor oligomerization. I. Disulfide trapping reveals oligomers and potential contact surfaces in a G protein-coupled receptor

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A rhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system

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Amino acids of the alpha1B-adrenergic receptor involved in agonist binding: differences in docking catecholamines to receptor subtypes

1 reference

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based on heuristic

inferred from PubMed ID database lookup

In vitro coexpression and pharmacological rescue of mutant gonadotropin-releasing hormone receptors causing hypogonadotropic hypogonadism in humans expressing compound heterozygous alleles

1 reference

https://pubmed.ncbi.nlm.nih.gov/18764782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seven transmembrane receptor core signaling complexes are assembled prior to plasma membrane trafficking

1 reference

https://pubmed.ncbi.nlm.nih.gov/18764782

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ20081227

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

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