(Q39956317)

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Protein kinase C-mediated phosphorylation of p47 phox modulates platelet-derived growth factor-induced H2O2 generation and cell proliferation in human umbilical vein endothelial cells

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scholarly article

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Europe PubMed Central

PubMed publication ID

15 September 2017

Protein kinase C-mediated phosphorylation of p47 phox modulates platelet-derived growth factor-induced H2O2 generation and cell proliferation in human umbilical vein endothelial cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

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phosphorylation

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author name string

F Simon

1

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

A Stutzin

2

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

publication date

1 July 2008

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Endothelium: Journal of Endothelial Cell Research

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Europe PubMed Central

PubMed publication ID

15 September 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

175-188

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Europe PubMed Central

PubMed publication ID

15 September 2017

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Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby acti

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The neutrophil NADPH oxidase

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Superoxide and hydrogen peroxide in relation to mammalian cell proliferation

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Control of cell proliferation by reactive oxygen species

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Protein kinase C zeta phosphorylates a subset of selective sites of the NADPH oxidase component p47phox and participates in formyl peptide-mediated neutrophil respiratory burst

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Permanent cell line expressing human factor VIII-related antigen established by hybridization

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Phosphorylation of the respiratory burst oxidase subunit p47phox as determined by two-dimensional phosphopeptide mapping. Phosphorylation by protein kinase C, protein kinase A, and a mitogen-activated protein kinase

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The phosphorylation targets of p47phox, a subunit of the respiratory burst oxidase. Functions of the individual target serines as evaluated by site-directed mutagenesis

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Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation

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PKC-delta-dependent pathways contribute to PDGF-stimulated ERK1/2 activation in vascular smooth muscle

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Lipid peroxide-induced redox imbalance differentially mediates CaCo-2 cell proliferation and growth arrest

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Modulation of p47 PHOX activity by site-specific phosphorylation: Akt-dependent activation of the NADPH oxidase

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Activation of the leukocyte NADPH oxidase by phorbol ester requires the phosphorylation of p47PHOX on serine 303 or 304.

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Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

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Activation of p47(PHOX), a cytosolic subunit of the leukocyte NADPH oxidase. Phosphorylation of ser-359 or ser-370 precedes phosphorylation at other sites and is required for activity.

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Colony-stimulating factor-1 requires PI3-kinase-mediated metabolism for proliferation and survival in myeloid cells

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Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor

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The requirement of p47 phosphorylation for activation of NADPH oxidase by opsonized zymosan in human neutrophils

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Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells

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Activation of the leukocyte NADPH oxidase by protein kinase C in a partially recombinant cell-free system.

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Low concentration of oxidant and nitric oxide donors stimulate proliferation of human endothelial cells in vitro.

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Activation of the leukocyte NADPH oxidase subunit p47phox by protein kinase C. A phosphorylation-dependent change in the conformation of the C-terminal end of p47phox.

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NOX2 and NOX4 mediate proliferative response in endothelial cells.

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Ligand-independent trans-activation of the platelet-derived growth factor receptor by reactive oxygen species requires protein kinase C-delta and c-Src

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Molecular composition and regulation of the Nox family NAD(P)H oxidases

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Requirement for generation of H2O2 for platelet-derived growth factor signal transduction

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Identifiers

10.1080/10623320802174480

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

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