(Q39957163)

15 September 2017

title

Regulatory T cells in transplantation: what we know and what we do not know (English)

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15 September 2017

M Y Yeung

1

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15 September 2017

M H Sayegh

series ordinal

2

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15 September 2017

language of work or name

English

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publication date

10 July 2009

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Transplantation Proceedings

15 September 2017

published in

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15 September 2017

volume

41

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15 September 2017

issue

6 Suppl

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15 September 2017

page(s)

S21-6

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Control of regulatory T cell development by the transcription factor Foxp3

15 September 2017

cites work

1 reference

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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

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Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

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From vanilla to 28 flavors: multiple varieties of T regulatory cells

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Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

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Human regulatory T cells: role in autoimmune disease and therapeutic opportunities

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CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

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The balance of deletion and regulation in allograft tolerance.

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The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

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Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells

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Human T regulatory cells can use the perforin pathway to cause autologous target cell death

7 January 2021

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Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism

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Regulatory T cells differentially modulate the maturation and apoptosis of human CD8+ T-cell subsets.

7 January 2021

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IL-10 Is Required for Regulatory T Cells to Mediate Tolerance to Alloantigens In Vivo

7 January 2021

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CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes

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CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms

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T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation

7 January 2021

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A unique subset of CD4+CD25highFoxp3+ T cells secreting interleukin-10 and transforming growth factor-beta1 mediates suppression in the tumor microenvironment

7 January 2021

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CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade

7 January 2021

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Tracking the immunoregulatory mechanisms active during allograft tolerance.

7 January 2021

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Regulatory T cells in transplantation.

7 January 2021

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Regulatory T cells in transplantation tolerance

7 January 2021

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Induction of transplantation tolerance-the potential of regulatory T cells

7 January 2021

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Alloreactive T cell responses and acute rejection of single class II MHC-disparate heart allografts are under strict regulation by CD4+ CD25+ T cells.

7 January 2021

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Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function

7 January 2021

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Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

7 January 2021

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7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Cutting Edge: Anti-CD154 Therapeutic Antibodies Induce Infectious Transplantation Tolerance

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https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

"Infectious" transplantation tolerance.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

Therapeutic vaccination using CD4+CD25+ antigen-specific regulatory T cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes

7 January 2021

1 reference

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Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice

7 January 2021

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Specificity of CD4+CD25+ regulatory T cell function in alloimmunity

7 January 2021

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Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes

7 January 2021

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In vitro-expanded donor alloantigen-specific CD4+CD25+ regulatory T cells promote experimental transplantation tolerance

7 January 2021

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Understanding FOXP3: progress towards achieving transplantation tolerance

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

Contrasting CD25hiCD4+T cells/FOXP3 patterns in chronic rejection and operational drug-free tolerance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

Multiparameter immune profiling of operational tolerance in liver transplantation

7 January 2021

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FoxP3 in peripheral blood is associated with operational tolerance in liver transplant patients during immunosuppression withdrawal.

7 January 2021

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Regulatory CD25+ T cells in human kidney transplant recipients

7 January 2021

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Achieving donor-specific hyporesponsiveness is associated with FOXP3+ regulatory T cell recruitment in human renal allograft infiltrates.

7 January 2021

1 reference

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The presence of Foxp3 expressing T cells within grafts of tolerant human liver transplant recipients

7 January 2021

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Messenger RNA for FOXP3 in the urine of renal-allograft recipients

7 January 2021

1 reference

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A novel mechanism of action for anti-thymocyte globulin: induction of CD4+CD25+Foxp3+ regulatory T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

CD4+ regulatory T cells are spared from deletion by antilymphocyte serum, a polyclonal anti-T cell antibody.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

Regulatory T Cells and T Cell Depletion: Role of Immunosuppressive Drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

Rabbit ATG but not horse ATG promotes expansion of functional CD4+CD25highFOXP3+ regulatory T cells in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

CD4+ CD25+ FOXP3+ regulatory T cells increase de novo in kidney transplant patients after immunodepletion with Campath-1H.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

Interleukin 2 signaling is required for CD4(+) regulatory T cell function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

A potential side effect of cyclosporin A: inhibition of CD4(+)CD25(+) regulatory T cells in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

Contrasting effects of cyclosporine and rapamycin in de novo generation of alloantigen-specific regulatory T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

Effect of immunosuppressants on the expansion and function of naturally occurring regulatory T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

Differential effect of calcineurin inhibitors, anti-CD25 antibodies and rapamycin on the induction of FOXP3 in human T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

Calcineurin inhibitors, but not rapamycin, reduce percentages of CD4+CD25+FOXP3+ regulatory T cells in renal transplant recipients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

Combination of rapamycin and IL-2 increases de novo induction of human CD4(+)CD25(+)FOXP3(+) T cells

7 January 2021

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Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

Sirolimus versus cyclosporine therapy increases circulating regulatory T cells, but does not protect renal transplant patients given alemtuzumab induction from chronic allograft injury.

7 January 2021

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Randomised trial of basiliximab versus placebo for control of acute cellular rejection in renal allograft recipients. CHIB 201 International Study Group

7 January 2021

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Reduction of the occurrence of acute cellular rejection among renal allograft recipients treated with basiliximab, a chimeric anti-interleukin-2-receptor monoclonal antibody. United States Simulect Renal Study Group

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

A randomized, double-blind trial of basiliximab immunoprophylaxis plus triple therapy in kidney transplant recipients

7 January 2021

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Rabbit antithymocyte globulin versus basiliximab in renal transplantation

7 January 2021

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Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

7 January 2021

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Short-term anti-CD25 monoclonal antibody treatment and neogenetic CD4(+)CD25(high) regulatory T cells in kidney transplantation

7 January 2021

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The effect of costimulatory and interleukin 2 receptor blockade on regulatory T cells in renal transplantation

7 January 2021

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Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans.

7 January 2021

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CD4+ T-regulatory cells: toward therapy for human diseases.

7 January 2021

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Quantifying the frequency of alloreactive T cells in vivo: new answers to an old question

7 January 2021

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CD4+CD25+ regulatory T cells in transplantation: progress, challenges and prospects

7 January 2021

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Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes

7 January 2021

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Cutting Edge: CD28 Controls Peripheral Homeostasis of CD4+CD25+ Regulatory T Cells

7 January 2021

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CD28 controls differentiation of regulatory T cells from naive CD4 T cells

7 January 2021

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Absence of CD4CD25 regulatory T cell expansion in renal transplanted patients treated in vivo with Belatacept mediated CD28-CD80/86 blockade

7 January 2021

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Adaptive TGF-beta-dependent regulatory T cells control autoimmune diabetes and are a privileged target of anti-CD3 antibody treatment

7 January 2021

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CTLA-4 x Ig converts naive CD4+CD25- T cells into CD4+CD25+ regulatory T cells.

7 January 2021

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Special regulatory T cell review: The resurgence of the concept of contrasuppression in immunoregulation

7 January 2021

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CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

Toll-like receptor signalling on Tregs: to suppress or not to suppress?

7 January 2021

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Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice

7 January 2021

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Triggering of OX40 (CD134) on CD4(+)CD25+ T cells blocks their inhibitory activity: a novel regulatory role for OX40 and its comparison with GITR.

7 January 2021

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

7 January 2021

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Rapamycin, not cyclosporine, permits thymic generation and peripheral preservation of CD4+ CD25+ FoxP3+ T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRANSPROCEED.2009.06.093

Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients

7 January 2021

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Rapamycin, and not cyclosporin A, preserves the highly suppressive CD27+ subset of human CD4+CD25+ regulatory T cells

7 January 2021

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10.1016/J.TRANSPROCEED.2009.06.093

7 January 2021

Identifiers

DOI

1 reference

15 September 2017

1 reference