(Q39959127)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18641636%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

title

Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index (English)

1 reference

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11 January 2020

0 references

1 reference

1

1 reference

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11 January 2020

author name string

Helga Raab

2

1 reference

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11 January 2020

Suzanna Clark

3

1 reference

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11 January 2020

Sunil Bhakta

4

1 reference

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11 January 2020

Douglas D Leipold

5

1 reference

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11 January 2020

Sylvia Weir

6

1 reference

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11 January 2020

Yvonne Chen

7

1 reference

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11 January 2020

Michelle Simpson

8

1 reference

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11 January 2020

Siao Ping Tsai

9

1 reference

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11 January 2020

Mark S Dennis

10

1 reference

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11 January 2020

Yanmei Lu

11

1 reference

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11 January 2020

Y Gloria Meng

12

1 reference

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11 January 2020

Carl Ng

13

1 reference

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11 January 2020

Jihong Yang

14

1 reference

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11 January 2020

Chien C Lee

15

1 reference

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11 January 2020

Eileen Duenas

16

1 reference

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11 January 2020

Jeffrey Gorrell

17

1 reference

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11 January 2020

Viswanatham Katta

18

1 reference

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11 January 2020

Amy Kim

19

1 reference

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11 January 2020

Kevin McDorman

20

1 reference

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11 January 2020

Kelly Flagella

21

1 reference

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11 January 2020

Rayna Venook

22

1 reference

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11 January 2020

Sarajane Ross

23

1 reference

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11 January 2020

Susan D Spencer

24

1 reference

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11 January 2020

Wai Lee Wong

25

1 reference

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11 January 2020

Henry B Lowman

26

1 reference

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11 January 2020

Richard Vandlen

27

1 reference

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11 January 2020

Mark X Sliwkowski

28

1 reference

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11 January 2020

Richard H Scheller

29

1 reference

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11 January 2020

Paul Polakis

30

1 reference

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11 January 2020

William Mallet

31

1 reference

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11 January 2020

publication date

20 July 2008

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11 January 2020

1 reference

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11 January 2020

volume

26

1 reference

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11 January 2020

page(s)

925-932

1 reference

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11 January 2020

issue

8

1 reference

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https://scigraph.springernature.com/pub.10.1038/nbt.1480

11 January 2020

exact match

0 references

cites work

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7 January 2021

Upping the ante on antibodies.

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7 January 2021

Arming antibodies: prospects and challenges for immunoconjugates

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7 January 2021

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7 January 2021

Armed antibodies targeting the mucin repeats of the ovarian cancer antigen, MUC16, are highly efficacious in animal tumor models

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7 January 2021

Development of potent monoclonal antibody auristatin conjugates for cancer therapy

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7 January 2021

Effects of drug loading on the antitumor activity of a monoclonal antibody drug conjugate

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7 January 2021

A prostate-specific membrane antigen-targeted monoclonal antibody-chemotherapeutic conjugate designed for the treatment of prostate cancer

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7 January 2021

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7 January 2021

The development of antibody delivery systems to target cancer with highly potent maytansinoids

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7 January 2021

Reduction-alkylation strategies for the modification of specific monoclonal antibody disulfides

1 reference

7 January 2021

In vitro and in vivo activity of the maytansinoid immunoconjugate huN901-N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine against CD56+ multiple myeloma cells

1 reference

7 January 2021

Cantuzumab mertansine, a maytansinoid immunoconjugate directed to the CanAg antigen: a phase I, pharmacokinetic, and biologic correlative study

1 reference

7 January 2021

Enhanced activity of monomethylauristatin F through monoclonal antibody delivery: effects of linker technology on efficacy and toxicity

1 reference

7 January 2021

Potent antitumor activity of an auristatin-conjugated, fully human monoclonal antibody to prostate-specific membrane antigen

1 reference

7 January 2021

CR011, a fully human monoclonal antibody-auristatin E conjugate, for the treatment of melanoma

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7 January 2021

Structural characterization of the maytansinoid-monoclonal antibody immunoconjugate, huN901-DM1, by mass spectrometry

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7 January 2021

Rapid identification of reactive cysteine residues for site-specific labeling of antibody-Fabs

1 reference

7 January 2021

Cathepsin B-labile dipeptide linkers for lysosomal release of doxorubicin from internalizing immunoconjugates: model studies of enzymatic drug release and antigen-specific in vitro anticancer activity

1 reference

7 January 2021

cAC10-vcMMAE, an anti-CD30–monomethyl auristatin E conjugate with potent and selective antitumor activity

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7 January 2021

Toxicity of dolastatin 10 in mice, rats and dogs and its clinical relevance

1 reference

7 January 2021

Engineered antibody-drug conjugates with defined sites and stoichiometries of drug attachment.

1 reference

7 January 2021

One disulfide bond in front of the second heavy chain constant region is necessary and sufficient for effector functions of human IgG3 without a genetic hinge

1 reference

7 January 2021

Conversion of incomplete antibodies to direct agglutinins by mild reduction: evidence for segmental flexibility within the Fc fragment of immunoglobulin G

1 reference

7 January 2021

Changes in quaternary structure of IgG upon reduction of the interheavy-chain disulfide bond

1 reference

7 January 2021

Site-specific attachment to recombinant antibodies via introduced surface cysteine residues

1 reference

7 January 2021

Site-specific conjugation on serine right-arrow cysteine variant monoclonal antibodies

1 reference

7 January 2021

Therapeutic antibody fragments with prolonged in vivo half-lives

1 reference

7 January 2021

Structural effect of a recombinant monoclonal antibody on hinge region peptide bond hydrolysis.

1 reference

7 January 2021