(Q39982625)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18478568%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Tumour-mediated disruption of dendritic cell function: inhibiting the MEK1/2-p44/42 axis restores IL-12 production and Th1-generation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18478568%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

1

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7 January 2020

author name string

Lori Ann Mulcahy

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18478568%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Xing Wu Zhu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18478568%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Dearbhaile O'Donnell

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18478568%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Poulam M Patel

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18478568%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

language of work or name

English

0 references

publication date

1 August 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18478568%20AND%20SRC:MED&resulttype=core&format=json

International Journal of Cancer

7 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18478568%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

123

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18478568%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18478568%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

623-632

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18478568%20AND%20SRC:MED&resulttype=core&format=json

Dendritic cell dysfunction in cancer: a mechanism for immunosuppression

7 January 2020

cites work

1 reference

Tumor-host immune interactions and dendritic cell dysfunction

21 January 2018

1 reference

Processing of tumor-associated antigen by the proteasomes of dendritic cells controls in vivo T-cell responses.

21 January 2018

1 reference

Update on immunotherapy for melanoma

21 January 2018

1 reference

Altered CD8(+) T-cell responses when immunizing with multiepitope peptide vaccines

21 January 2018

1 reference

Emerging clinical applications of RNA

21 January 2018

1 reference

Immunosuppression in melanoma immunotherapy: potential opportunities for intervention

21 January 2018

1 reference

ATP gradients inhibit the migratory capacity of specific human dendritic cell types: implications for P2Y11 receptor signaling.

21 January 2018

1 reference

Dendritic cells in a mature age.

21 January 2018

1 reference

Bugs as drugs for cancer.

21 January 2018

1 reference

Toll-like receptors and dendritic cells: for whom the bug tolls

21 January 2018

1 reference

Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4

21 January 2018

1 reference

IFN-alpha enhances CD40 ligand-mediated activation of immature monocyte-derived dendritic cells.

21 January 2018

1 reference

Extracellular signal-regulated protein kinase signaling pathway negatively regulates the phenotypic and functional maturation of monocyte-derived human dendritic cells.

21 January 2018

1 reference

New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions

21 January 2018

1 reference

Monocyte-derived DC primed with TLR agonists secrete IL-12p70 in a CD40-dependent manner under hyperthermic conditions.

21 January 2018

1 reference

Optimizing immunotherapy in multiple myeloma: Restoring the function of patients' monocyte-derived dendritic cells by inhibiting p38 or activating MEK/ERK MAPK and neutralizing interleukin-6 in progenitor cells

21 January 2018

1 reference

Tumor evasion of the immune system: inhibiting p38 MAPK signaling restores the function of dendritic cells in multiple myeloma

21 January 2018

1 reference

Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway

21 January 2018

1 reference

Immune resistance orchestrated by the tumor microenvironment

21 January 2018

1 reference

Vascular endothelial growth factor inhibits maturation of dendritic cells induced by lipopolysaccharide, but not by proinflammatory cytokines

21 January 2018

1 reference

Prostaglandin E(2) is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer

21 January 2018

1 reference

Role of c-Jun N-terminal kinase on lipopolysaccharide induced maturation of human monocyte-derived dendritic cells

21 January 2018

1 reference

Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.

21 January 2018

1 reference

Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2.

21 January 2018

1 reference

Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice

21 January 2018

1 reference

Role of mitogen-activated protein kinases in CpG DNA-mediated IL-10 and IL-12 production: central role of extracellular signal-regulated kinase in the negative feedback loop of the CpG DNA-mediated Th1 response

21 January 2018

1 reference

Critical roles of Raf/MEK/ERK and PI3K/AKT signaling and inactivation of p38 MAP kinase in the differentiation and survival of monocyte-derived immature dendritic cells

21 January 2018

1 reference

DC-SIGN ligation on dendritic cells results in ERK and PI3K activation and modulates cytokine production.

21 January 2018

1 reference

Differential role of MAPK signaling in human dendritic cell maturation and Th1/Th2 engagement

21 January 2018

1 reference

p38 Mitogen-activated protein kinase and extracellular signal-regulated kinases play distinct roles in the activation of dendritic cells by two representative haptens, NiCl2 and 2,4-dinitrochlorobenzene

21 January 2018

1 reference

p38 Mitogen-Activated protein kinase mediates dual role of ultraviolet B radiation in induction of maturation and apoptosis of monocyte-derived dendritic cells

21 January 2018

1 reference

Insulin-like growth factor I promotes maturation and inhibits apoptosis of immature cord blood monocyte-derived dendritic cells through MEK and PI 3-kinase pathways.

21 January 2018

1 reference

Adoptive immunotherapy for cancer: building on success

21 January 2018

1 reference

Vaccination with tumor lysate-pulsed dendritic cells elicits antigen-specific, cytotoxic T-cells in patients with malignant glioma

21 January 2018

1 reference

Pilot study of treatment of biochemotherapy-refractory stage IV melanoma patients with autologous dendritic cells pulsed with a heterologous melanoma cell line lysate

21 January 2018

1 reference

CI-1040 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK)

21 January 2018

1 reference

Phase I and pharmacodynamic study of the oral MEK inhibitor CI-1040 in patients with advanced malignancies

21 January 2018

1 reference

Multicenter phase II study of the oral MEK inhibitor, CI-1040, in patients with advanced non-small-cell lung, breast, colon, and pancreatic cancer

21 January 2018

1 reference

IL10 and IL12B polymorphisms each influence IL-12p70 secretion by dendritic cells in response to LPS

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IJC.23530

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18478568%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference