(Q39990836)

English

A chimeric fusion of the hASH1 and EZH2 promoters mediates high and specific reporter and suicide gene expression and cytotoxicity in small cell lung cancer cells

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scholarly article

1 reference

Europe PubMed Central

16 September 2017

A chimeric fusion of the hASH1 and EZH2 promoters mediates high and specific reporter and suicide gene expression and cytotoxicity in small cell lung cancer cells (English)

1 reference

Europe PubMed Central

16 September 2017

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author name string

T T Poulsen

1

1 reference

Europe PubMed Central

16 September 2017

N Pedersen

2

1 reference

Europe PubMed Central

16 September 2017

H Juel

3

1 reference

Europe PubMed Central

16 September 2017

H S Poulsen

4

1 reference

Europe PubMed Central

16 September 2017

publication date

18 April 2008

1 reference

Europe PubMed Central

16 September 2017

Cancer Gene Therapy

1 reference

Europe PubMed Central

16 September 2017

15

1 reference

Europe PubMed Central

16 September 2017

9

1 reference

Europe PubMed Central

16 September 2017

563-575

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Europe PubMed Central

16 September 2017

https://scigraph.springernature.com/pub.10.1038/cgt.2008.24

0 references

Complicated mechanisms of class II transactivator transcription deficiency in small cell lung cancer and neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

21 January 2018

Management of small cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Replacement and suicide gene therapy for targeted treatment of lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Suicide gene therapy mediated by the Herpes Simplex virus thymidine kinase gene/Ganciclovir system: fifteen years of application.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Adenovirus-mediated suicide SCLC gene therapy using the increased activity of the hTERT promoter by the MMRE and SV40 enhancer.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Infectivity enhanced, hTERT promoter-based conditionally replicative adenoviruses are useful for SCLC treatment

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Use of gastrin-releasing peptide promoter for specific expression of thymidine kinase gene in small-cell lung carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

The insulinoma-associated 1: a novel promoter for targeted cancer gene therapy for small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

An achaete-scute homologue essential for neuroendocrine differentiation in the lung

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning, sequencing and expression of the mouse mammalian achaete-scute homolog 1 (MASH1).

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Mash1 specifies neurons and oligodendrocytes in the postnatal brain

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Conservation of the Drosophila lateral inhibition pathway in human lung cancer: a hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Notch signaling induces rapid degradation of achaete-scute homolog 1.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of the NOTCH1 intracellular domain inhibits cell proliferation and alters the neuroendocrine phenotype of medullary thyroid cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

The polycomb group protein EZH2 is involved in progression of prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of p16 and lack of pRB in primary small cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct pattern of E2F1 expression in human lung tumours: E2F1 is upregulated in small cell lung carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear overexpression of the E2F3 transcription factor in human lung cancer.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA repair rate and etoposide (VP16) resistance of tumor cell subpopulations derived from a single human small cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Establishment, growth properties, and morphological characteristics of permanent human small cell lung cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

The new World Health Organization classification of lung tumours

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

hASH1 expression is closely correlated with endocrine phenotype and differentiation extent in pulmonary neuroendocrine tumors

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Ezh2 reduces the ability of HDAC1-dependent pRb2/p130 transcriptional repression of cyclin A.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Neuroblastoma-specific cytotoxicity mediated by the Mash1-promoter and E. coli purine nucleoside phosphorylase.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of myc family oncoproteins in small-cell lung-cancer cell lines and xenografts

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel MASH1 enhancer with N-myc and CREB-binding sites is active in neuroblastoma.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Lineage-specific regulation of the neural differentiation gene MASH1.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.24

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/CGT.2008.24

1 reference

Europe PubMed Central

16 September 2017

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1 reference

Europe PubMed Central

16 September 2017

ResearchGate publication ID

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