(Q40005465)

16 September 2017

title

Nonsense-mediated mRNA decay (NMD) mechanisms (English)

1 reference

16 September 2017

Saverio Brogna

1

1 reference

16 September 2017

Jikai Wen

series ordinal

2

1 reference

16 September 2017

publication date

1 February 2009

1 reference

Nature Structural & Molecular Biology

16 September 2017

published in

1 reference

16 September 2017

volume

16

1 reference

16 September 2017

issue

2

1 reference

16 September 2017

page(s)

107-113

1 reference

Polarity and the Degradation of mRNA

16 September 2017

cites work

1 reference

Early nonsense: mRNA decay solves a translational problem

21 January 2018

1 reference

Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics

21 January 2018

1 reference

Nonsense-mediated mRNA decay: molecular insights and mechanistic variations across species

21 January 2018

1 reference

Mutations in the MOF2/SUI1 gene affect both translation and nonsense-mediated mRNA decay.

21 January 2018

1 reference

An internal open reading frame triggers nonsense-mediated decay of the yeast SPT10 mRNA.

21 January 2018

1 reference

SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast

21 January 2018

1 reference

SMG-1 is a phosphatidylinositol kinase-related protein kinase required for nonsense-mediated mRNA Decay in Caenorhabditis elegans

21 January 2018

1 reference

SMG7 acts as a molecular link between mRNA surveillance and mRNA decay

21 January 2018

1 reference

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

21 January 2018

1 reference

Stabilization and ribosome association of unspliced pre-mRNAs in a yeast upf1- mutant

21 January 2018

1 reference

Widespread impact of nonsense-mediated mRNA decay on the yeast intronome

21 January 2018

1 reference

Alternative splicing resulting in nonsense-mediated mRNA decay: what is the meaning of nonsense?

21 January 2018

1 reference

Nonsense-mediated mRNA decay: target genes and functional diversification of effectors

21 January 2018

1 reference

Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability

21 January 2018

1 reference

Functions of the nonsense-mediated mRNA decay pathway in Drosophila development

21 January 2018

1 reference

Arabidopsis UPF1 RNA helicase for nonsense-mediated mRNA decay is involved in seed size control and is essential for growth

21 January 2018

1 reference

NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements

21 January 2018

1 reference

Unexpected roles for UPF1 in HIV-1 RNA metabolism and translation

21 January 2018

1 reference

The human RNA surveillance factor UPF1 is required for S phase progression and genome stability

21 January 2018

1 reference

Saccharomyces cerevisiae Ebs1p is a putative ortholog of human Smg7 and promotes nonsense-mediated mRNA decay

21 January 2018

1 reference

Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends

21 January 2018

1 reference

The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells

21 January 2018

1 reference

Identification and characterization of a sequence motif involved in nonsense-mediated mRNA decay

21 January 2018

1 reference

mRNA surveillance in eukaryotes: kinetic proofreading of proper translation termination as assessed by mRNP domain organization?

21 January 2018

1 reference

Aberrant mRNAs with extended 3' UTRs are substrates for rapid degradation by mRNA surveillance

21 January 2018

1 reference

A faux 3'-UTR promotes aberrant termination and triggers nonsense-mediated mRNA decay

21 January 2018

1 reference

The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein

21 January 2018

1 reference

Poly(A)-binding protein acts in translation termination via eukaryotic release factor 3 interaction and does not influence [PSI(+)] propagation

21 January 2018

1 reference

At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: a possible link between nuclear splicing and cytoplasmic translation

21 January 2018

1 reference

Binary specification of nonsense codons by splicing and cytoplasmic translation

21 January 2018

1 reference

The human intronless melanocortin 4-receptor gene is NMD insensitive

21 January 2018

1 reference

Mammalian heat shock p70 and histone H4 transcripts, which derive from naturally intronless genes, are immune to nonsense-mediated decay

21 January 2018

1 reference

A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance

21 January 2018

1 reference

The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay

21 January 2018

1 reference

NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity

21 January 2018

1 reference

Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20

21 January 2018

1 reference

The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling

21 January 2018

1 reference

The ever-increasing complexities of the exon junction complex

21 January 2018

1 reference

Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)

21 January 2018

1 reference

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

21 January 2018

1 reference

Efficient downregulation of immunoglobulin mu mRNA with premature translation-termination codons requires the 5'-half of the VDJ exon

21 January 2018

1 reference

Boundary-independent polar nonsense-mediated decay

21 January 2018

1 reference

Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways

21 January 2018

1 reference

Mechanistic insights and identification of two novel factors in the C. elegans NMD pathway.

21 January 2018

1 reference

A conserved role for cytoplasmic poly(A)-binding protein 1 (PABPC1) in nonsense-mediated mRNA decay

21 January 2018

1 reference

Proximity of the poly(A)-binding protein to a premature termination codon inhibits mammalian nonsense-mediated mRNA decay

21 January 2018

1 reference

EJC-independent degradation of nonsense immunoglobulin-mu mRNA depends on 3' UTR length.

21 January 2018

1 reference

A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay

21 January 2018

1 reference

Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region

21 January 2018

1 reference

Interference of nonsense mutations with eukaryotic messenger RNA stability

21 January 2018

1 reference

Nonsense mutations in the alcohol dehydrogenase gene of Drosophila melanogaster correlate with an abnormal 3' end processing of the corresponding pre-mRNA.

21 January 2018

1 reference

Initiation of translation can occur only in a restricted region of the CYC1 mRNA of Saccharomyces cerevisiae

21 January 2018

1 reference

Translation factors promote the formation of two states of the closed-loop mRNP.

21 January 2018

1 reference

A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation

21 January 2018

1 reference

Translation initiation factors eIF-iso4G and eIF-4B interact with the poly(A)-binding protein and increase its RNA binding activity

21 January 2018

1 reference

Nonsense-mediated decay does not occur within the yeast nucleus

21 January 2018

1 reference

Nonsense but not missense mutations can decrease the abundance of nuclear mRNA for the mouse major urinary protein, while both types of mutations can facilitate exon skipping

21 January 2018

1 reference

Evidence that translation reinitiation abrogates nonsense-mediated mRNA decay in mammalian cells

21 January 2018

1 reference

Nonsense mutations in close proximity to the initiation codon fail to trigger full nonsense-mediated mRNA decay.

21 January 2018

1 reference

What determines whether mammalian ribosomes resume scanning after translation of a short upstream open reading frame?

21 January 2018

1 reference

eIF3a cooperates with sequences 5' of uORF1 to promote resumption of scanning by post-termination ribosomes for reinitiation on GCN4 mRNA.

21 January 2018

1 reference

Mammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanisms

21 January 2018

1 reference

Cap-independent translation is required for starvation-induced differentiation in yeast

21 January 2018

1 reference

mRNA stabilization by poly(A) binding protein is independent of poly(A) and requires translation.

21 January 2018

1 reference

Nonsense-mediated mRNA decay in yeast does not require PAB1 or a poly(A) tail

21 January 2018

1 reference

A specific role for the C-terminal region of the Poly(A)-binding protein in mRNA decay

21 January 2018

1 reference

Splicing and 3' end formation in the definition of nonsense-mediated decay-competent human beta-globin mRNPs

21 January 2018

1 reference

The histone 3'-terminal stem-loop-binding protein enhances translation through a functional and physical interaction with eukaryotic initiation factor 4G (eIF4G) and eIF3

21 January 2018

1 reference

Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1

21 January 2018

1 reference

Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay

21 January 2018

1 reference

Human INT6/eIF3e is required for nonsense-mediated mRNA decay

21 January 2018

1 reference

Recycling of eukaryotic posttermination ribosomal complexes

21 January 2018

1 reference

Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities

21 January 2018

1 reference

Nonsense-mediated messenger RNA decay is initiated by endonucleolytic cleavage in Drosophila

21 January 2018

1 reference

SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan

21 January 2018

1 reference

SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells

21 January 2018

1 reference

Association of yeast Upf1p with direct substrates of the NMD pathway.

21 January 2018

1 reference

Step-wise formation of eukaryotic double-row polyribosomes and circular translation of polysomal mRNA.

21 January 2018

1 reference

A novel role of the mammalian GSPT/eRF3 associating with poly(A)-binding protein in Cap/Poly(A)-dependent translation

21 January 2018

1 reference

Failsafe nonsense-mediated mRNA decay does not detectably target eIF4E-bound mRNA

21 January 2018

1 reference

A quantitative analysis of intron effects on mammalian gene expression

21 January 2018

1 reference

SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs

21 January 2018

1 reference

Ribosome components are associated with sites of transcription.

21 January 2018

1 reference

Coupled transcription and translation within nuclei of mammalian cells.

21 January 2018

1 reference

NASty effects on fibrillin pre-mRNA splicing: another case of ESE does it, but proposals for translation-dependent splice site choice live on.

21 January 2018

1 reference

Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements

21 January 2018

1 reference

An alternative branch of the nonsense-mediated decay pathway

21 January 2018

1 reference

Translational control of intron splicing in eukaryotes

21 January 2018

1 reference

mRNA destabilization triggered by premature translational termination depends on at least three cis-acting sequence elements and one trans-acting factor

21 January 2018

1 reference

The yeast hnRNP-like protein Hrp1/Nab4 marks a transcript for nonsense-mediated mRNA decay

31 March 2020

1 reference

Shape of large bound polysomes in cultured fibroblasts and thyroid epithelial cells

31 March 2020

1 reference

Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life.

31 March 2020

1 reference

smg-7 is required for mRNA surveillance in Caenorhabditis elegans.

31 March 2020

1 reference

12 December 2020

Nonsense mutations in the human beta-globin gene lead to unexpected levels of cytoplasmic mRNA accumulation

1 reference

12 December 2020

A splicing-dependent regulatory mechanism that detects translation signals

1 reference

12 December 2020

Poly(A)-binding proteins: multifunctional scaffolds for the post-transcriptional control of gene expression

1 reference

12 December 2020

Frameshift suppression Saccharomyces cerevisiae. II. Genetic properties of group II suppressors.

1 reference

12 December 2020

When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells.

1 reference

12 December 2020

A new kind of informational suppression in the nematode Caenorhabditis elegans

1 reference

12 December 2020

Identifiers

DOI

10.1038/NSMB.1550

1 reference

Dimensions Publication ID

16 September 2017

1005363300

0 references

Fatcat ID

release_idirkgc4yjeqbfuq3ldtjqwo74

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/idirkgc4yjeqbfuq3ldtjqwo74

24 November 2022

mapped directly with Wikidata item

1 reference