(Q40006411)

English

E1a gene expression blocks the ERK1/2 signaling pathway by promoting nuclear localization and MKP up-regulation: implication in v-H-Ras-induced senescence

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scholarly article

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Europe PubMed Central

PubMed publication ID

16 September 2017

E1a gene expression blocks the ERK1/2 signaling pathway by promoting nuclear localization and MKP up-regulation: implication in v-H-Ras-induced senescence (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

author name string

Juan L Callejas-Valera

1

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Europe PubMed Central

PubMed publication ID

16 September 2017

Juan Guinea-Viniegra

2

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Europe PubMed Central

PubMed publication ID

16 September 2017

Carmen Ramírez-Castillejo

3

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Europe PubMed Central

PubMed publication ID

16 September 2017

Juan A Recio

4

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Europe PubMed Central

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16 September 2017

Eva Galan-Moya

5

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Natalia Martinez

6

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Europe PubMed Central

PubMed publication ID

16 September 2017

Jose M Rojas

7

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Santiago Ramón y Cajal

8

1 reference

Europe PubMed Central

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16 September 2017

Ricardo Sánchez-Prieto

9

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PubMed publication ID

16 September 2017

language of work or name

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publication date

3 March 2008

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16 September 2017

Journal of Biological Chemistry

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16 September 2017

283

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PubMed publication ID

16 September 2017

19

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PubMed publication ID

16 September 2017

13450-13458

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Europe PubMed Central

PubMed publication ID

16 September 2017

RAS oncogenes: the first 30 years.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Tumour biology: senescence in premalignant tumours

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Cellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

PEA-15 is inhibited by adenovirus E1A and plays a role in ERK nuclear export and Ras-induced senescence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Defined genetic events associated with the spontaneous in vitro transformation of ElA/Ras-expressing human IMR90 fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Regulation of the activity of p38 mitogen-activated protein kinase by Akt in cancer and adenoviral protein E1A-mediated sensitization to apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Modulation of PI3K/Akt pathway by E1a mediates sensitivity to cisplatin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

A new role of protein phosphatase 2a in adenoviral E1A protein-mediated sensitization to anticancer drug-induced apoptosis in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Positive regulation of Raf1-MEK1/2-ERK1/2 signaling by protein serine/threonine phosphatase 2A holoenzymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Diverse physiological functions for dual-specificity MAP kinase phosphatases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Modulation of replicative senescence of diploid human cells by nuclear ERK signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Metabolic stabilization of MAP kinase phosphatase-2 in senescence of human fibroblasts.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

C-terminal splicing of NTPDase2 provides distinctive catalytic properties, cellular distribution and enzyme regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Akt down-regulates ERK1/2 nuclear localization and angiotensin II-induced cell proliferation through PEA-15.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

The ability of E1A to rescue ras-induced premature senescence and confer transformation relies on inactivation of both p300/CBP and Rb family proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Adenovirus-5 E1A: paradox and paradigm

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

PEA-15 inhibits tumor cell invasion by binding to extracellular signal-regulated kinase 1/2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Phosphoprotein enriched in astrocytes-15 kDa expression inhibits astrocyte migration by a protein kinase C delta-dependent mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

A negative feedback signaling network underlies oncogene-induced senescence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

The power and the promise of oncogene-induced senescence markers.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

MAPK pathways in radiation responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709230200

21 January 2018

Identifiers

10.1074/JBC.M709230200

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

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