(Q40013277)

English

Homozygous deletions may be markers of nearby heterozygous mutations: The complex deletion at FRA16D in the HCT116 colon cancer cell line removes exons of WWOX.

scientific article published on May 2008

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2 January 2020

Homozygous deletions may be markers of nearby heterozygous mutations: The complex deletion at FRA16D in the HCT116 colon cancer cell line removes exons of WWOX (English)

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2 January 2020

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cancer cell line

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4

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2 January 2020

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2 January 2020

author name string

Amber E Alsop

1

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2 January 2020

Karen Taylor

2

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2 January 2020

Jieqing Zhang

3

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2 January 2020

Paul A W Edwards

6

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2 January 2020

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publication date

1 May 2008

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2 January 2020

Genes, Chromosomes and Cancer

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2 January 2020

47

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2 January 2020

5

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2 January 2020

437-447

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2 January 2020

Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement.

1 reference

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7 January 2021

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Characterizing the chromosomes of the Australian model marsupial Macropus eugenii (tammar wallaby)

1 reference

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7 January 2021

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Distribution of breakpoints on chromosome 18 in breast, colorectal, and pancreatic carcinoma cell lines

1 reference

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7 January 2021

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Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2gamma transcription factor

1 reference

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7 January 2021

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Functional association between Wwox tumor suppressor protein and p73, a p53 homolog

1 reference

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7 January 2021

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WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20548

7 January 2021

based on heuristic

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Targeted deletion of Wwox reveals a tumor suppressor function

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20548

7 January 2021

based on heuristic

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Chromosome 3p14 homozygous deletions and sequence analysis of FRA3B.

1 reference

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7 January 2021

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Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity

1 reference

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7 January 2021

based on heuristic

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A survey of homozygous deletions in human cancer genomes

1 reference

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7 January 2021

based on heuristic

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Alternative transcripts of the candidate tumor suppressor gene, WWOX, are expressed at high levels in human breast tumors.

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20548

7 January 2021

based on heuristic

inferred from DOI database lookup

WWOX gene restoration prevents lung cancer growth in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20548

7 January 2021

based on heuristic

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Common chromosomal fragile site FRA16D mutation in cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20548

7 January 2021

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The complex nature of constitutional de novo apparently balanced translocations in patients presenting with abnormal phenotypes

1 reference

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7 January 2021

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DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

1 reference

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7 January 2021

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Sequence of the FRA3B common fragile region: implications for the mechanism of FHIT deletion

1 reference

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7 January 2021

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A cell cycle regulator potentially involved in genesis of many tumor types

1 reference

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7 January 2021

based on heuristic

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The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20548

7 January 2021

based on heuristic

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Frequent loss of WWOX expression in breast cancer: correlation with estrogen receptor status

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20548

7 January 2021

based on heuristic

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WWOX protein expression varies among ovarian carcinoma histotypes and correlates with less favorable outcome

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20548

7 January 2021

based on heuristic

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Common chromosomal fragile sites and cancer: focus on FRA16D.

1 reference

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7 January 2021

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Circular binary segmentation for the analysis of array-based DNA copy number data

1 reference

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7 January 2021

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WWOX: a candidate tumor suppressor gene involved in multiple tumor types

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20548

7 January 2021

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Characterization of the tumor suppressor gene WWOX in primary human oral squamous cell carcinomas.

1 reference

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7 January 2021

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High-resolution analysis of chromosome rearrangements on 8p in breast, colon and pancreatic cancer reveals a complex pattern of loss, gain and translocation

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20548

7 January 2021

based on heuristic

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Saccharomyces cerevisiae as a model system to define the chromosomal instability phenotype.

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20548

7 January 2021

based on heuristic

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Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20548

7 January 2021

based on heuristic

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Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region.

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20548

7 January 2021

based on heuristic

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Identifiers

10.1002/GCC.20548

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18273838%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18273838%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

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