(Q40019581)

English

Wnt/beta-catenin signaling stimulates matrix catabolic genes and activity in articular chondrocytes: its possible role in joint degeneration

scientific article published on 28 January 2008

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scholarly article

1 reference

Europe PubMed Central

16 September 2017

Wnt/beta-catenin signaling stimulates matrix catabolic genes and activity in articular chondrocytes: its possible role in joint degeneration (English)

1 reference

Europe PubMed Central

16 September 2017

author name string

Takahito Yuasa

1

1 reference

Europe PubMed Central

16 September 2017

Tomohiro Otani

2

1 reference

Europe PubMed Central

16 September 2017

Tatsuya Koike

3

1 reference

Europe PubMed Central

16 September 2017

Masahiro Iwamoto

4

1 reference

Europe PubMed Central

16 September 2017

Motomi Enomoto-Iwamoto

5

1 reference

Europe PubMed Central

16 September 2017

publication date

28 January 2008

1 reference

Europe PubMed Central

16 September 2017

Laboratory Investigation

1 reference

Europe PubMed Central

16 September 2017

88

1 reference

Europe PubMed Central

16 September 2017

3

1 reference

Europe PubMed Central

16 September 2017

264-274

1 reference

Europe PubMed Central

16 September 2017

https://scigraph.springernature.com/pub.10.1038/labinvest.3700747

0 references

1 reference

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7 January 2021

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New aspects of Wnt signaling pathways in higher vertebrates

1 reference

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7 January 2021

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Wnt signalling: pathway or network?

1 reference

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7 January 2021

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Wnt signaling: a common theme in animal development

1 reference

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7 January 2021

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WNTs modulate cell fate and behavior during vertebrate development

1 reference

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A new member of the frizzled family from Drosophila functions as a Wingless receptor

1 reference

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Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein

1 reference

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Secreted antagonists of the Wnt signalling pathway

1 reference

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Regulation of LEF-1/TCF transcription factors by Wnt and other signals

1 reference

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7 January 2021

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Beta-catenin: a key mediator of Wnt signaling

1 reference

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Matrix metalloproteinases: role in arthritis

1 reference

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The role of cytokines in cartilage matrix degeneration in osteoarthritis.

1 reference

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Lessons from animal models of arthritis

1 reference

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7 January 2021

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The Wnt antagonist Frzb-1 regulates chondrocyte maturation and long bone development during limb skeletogenesis

1 reference

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7 January 2021

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Developmental regulation of Wnt/beta-catenin signals is required for growth plate assembly, cartilage integrity, and endochondral ossification.

1 reference

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7 January 2021

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Regulation of beta-catenin signaling and maintenance of chondrocyte differentiation by ubiquitin-independent proteasomal degradation of alpha-catenin.

1 reference

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7 January 2021

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Opposing roles of WNT-5A and WNT-11 in interleukin-1beta regulation of type II collagen expression in articular chondrocytes.

1 reference

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7 January 2021

based on heuristic

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Alteration of matrix glycosaminoglycans diminishes articular chondrocytes' response to a canonical Wnt signal

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

How proteases regulate bone morphogenesis

1 reference

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7 January 2021

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Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700747

7 January 2021

based on heuristic

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Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossification

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700747

7 January 2021

based on heuristic

inferred from DOI database lookup

Bone morphogenetic protein signaling is required for maintenance of differentiated phenotype, control of proliferation, and hypertrophy in chondrocytes

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700747

7 January 2021

based on heuristic

inferred from DOI database lookup

Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700747

7 January 2021

based on heuristic

inferred from DOI database lookup

Retinoic acid induces rapid mineralization and expression of mineralization-related genes in chondrocytes

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700747

7 January 2021

based on heuristic

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Effects of hyaluronic acid on the release of proteoglycan from the cell matrix in rabbit chondrocyte cultures in the presence and absence of cytokines

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700747

7 January 2021

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A comparative analysis of bone and cartilage metabolism in two strains of guinea-pig with varying degrees of naturally occurring osteoarthritis

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700747

7 January 2021

based on heuristic

inferred from DOI database lookup

Wnt-3a regulates chondrocyte differentiation via c-Jun/AP-1 pathway.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700747

7 January 2021

based on heuristic

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Matrix metalloproteinases and TIMPs: properties and implications for the rheumatic diseases

1 reference

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7 January 2021

based on heuristic

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Selective activation of the mitogen-activated protein kinase subgroups c-Jun NH2 terminal kinase and p38 by IL-1 and TNF in human articular chondrocytes

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700747

7 January 2021

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IL-1- and TNF-induced bone resorption is mediated by p38 mitogen activated protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700747

7 January 2021

based on heuristic

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Inhibition of interleukin-1-stimulated MAP kinases, activating protein-1 (AP-1) and nuclear factor kappa B (NF-kappa B) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700747

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of the chondrocyte phenotype by beta-catenin

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700747

7 January 2021

based on heuristic

inferred from DOI database lookup

Wnt-7a causes loss of differentiated phenotype and inhibits apoptosis of articular chondrocytes via different mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700747

7 January 2021

based on heuristic

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Chondrocyte response to growth factors is modulated by p38 mitogen-activated protein kinase inhibition

1 reference

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7 January 2021

based on heuristic

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beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer

1 reference

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7 January 2021

based on heuristic

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Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels

1 reference

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7 January 2021

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Induction of chondrogenesis in limb mesenchymal cultures by disruption of the actin cytoskeleton

1 reference

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7 January 2021

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Osteoarthritis cartilage histopathology: grading and staging.

1 reference

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Focal adhesion kinase and mitogen-activated protein kinases are involved in chondrocyte activation by the 29-kDa amino-terminal fibronectin fragment

1 reference

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Molecular mechanisms of cartilage destruction: mechanics, inflammatory mediators, and aging collide

1 reference

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7 January 2021

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Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1.

1 reference

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PTEN and GSK3beta: key regulators of progression to androgen-independent prostate cancer

1 reference

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Expression and function of wingless and frizzled homologs in rheumatoid arthritis.

1 reference

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7 January 2021

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Expression profiles and functional analyses of Wnt-related genes in human joint disorders

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3700747

7 January 2021

based on heuristic

inferred from DOI database lookup

Secreted Frizzled-related proteins: searching for relationships and patterns

1 reference

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7 January 2021

based on heuristic

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Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females.

1 reference

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7 January 2021

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Sex and ethnic differences in the association ofASPN,CALM1,COL2A1,COMP, andFRZB with genetic susceptibility to osteoarthritis of the knee

1 reference

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7 January 2021

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Identifiers

10.1038/LABINVEST.3700747

1 reference

Europe PubMed Central

16 September 2017

1 reference

Europe PubMed Central

16 September 2017

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