(Q40036683)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18073214%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18073214%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

1

1 reference

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29 December 2019

Amar Abderrahmani

4

1 reference

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Jacques-Antoine Haefliger

29 December 2019

6

1 reference

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29 December 2019

author name string

Florian Alonso

2

1 reference

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29 December 2019

David Martin

3

1 reference

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29 December 2019

Gérard Waeber

5

1 reference

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29 December 2019

language of work or name

English

0 references

publication date

11 December 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18073214%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

29 December 2019

published in

1 reference

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29 December 2019

volume

283

1 reference

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29 December 2019

issue

9

1 reference

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29 December 2019

page(s)

5226-5234

1 reference

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Involvement of gap junctional communication in secretion

29 December 2019

cites work

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Connexin-36 contributes to control function of insulin-producing cells.

21 January 2018

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Replacement by a lacZ reporter gene assigns mouse connexin36, 45 and 43 to distinct cell types in pancreatic islets.

21 January 2018

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Lentivirus-mediated transduction of connexin cDNAs shows level- and isoform-specific alterations in insulin secretion of primary pancreatic beta-cells

21 January 2018

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21 January 2018

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Minireview: Secondary beta-cell failure in type 2 diabetes--a convergence of glucotoxicity and lipotoxicity

21 January 2018

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Glucose represses connexin36 in insulin-secreting cells.

21 January 2018

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Free fatty acids and pathogenesis of type 2 diabetes mellitus

21 January 2018

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Free fatty acids and insulin secretion in humans

21 January 2018

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Free fatty acids and type 2 diabetes mellitus

21 January 2018

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Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle

21 January 2018

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Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation

21 January 2018

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New insights into fatty acid modulation of pancreatic beta-cell function.

21 January 2018

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Pleiotropic effects of fatty acids on pancreatic beta-cells

21 January 2018

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Fatty acids, lipotoxicity and insulin secretion

21 January 2018

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Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor.

21 January 2018

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ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis

21 January 2018

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Linoleic acid and antioxidants protect against DNA damage and apoptosis induced by palmitic acid

21 January 2018

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Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

21 January 2018

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Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells

21 January 2018

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Differential gene expression in well-regulated and dysregulated pancreatic beta-cell (MIN6) sublines

21 January 2018

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Long-lasting antidiabetic effect of a dipeptidyl peptidase IV-resistant analog of glucagon-like peptide-1.

21 January 2018

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Partial gene deletion of endothelial nitric oxide synthase predisposes to exaggerated high-fat diet-induced insulin resistance and arterial hypertension

21 January 2018

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Critical role of the transcriptional repressor neuron-restrictive silencer factor in the specific control of connexin36 in insulin-producing cell lines

21 January 2018

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Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1.

21 January 2018

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Palmitate potentiation of glucose-induced insulin release: a study using 2-bromopalmitate

21 January 2018

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Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids

21 January 2018

1 reference

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Mechanisms involved in the cytotoxic and cytoprotective actions of saturated versus monounsaturated long-chain fatty acids in pancreatic beta-cells

21 January 2018

1 reference

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Overexpression of repressive cAMP response element modulators in high glucose and fatty acid-treated rat islets. A common mechanism for glucose toxicity and lipotoxicity?

21 January 2018

1 reference

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Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.

21 January 2018

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Diabetes: insulin resistance and derangements in lipid metabolism. Cure through intervention in fat transport and storage

21 January 2018

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Regulation of insulin secretion and expression of SUR1 gene by chronic exposure to free fatty acids in rat pancreatic beta cells

21 January 2018

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Fatty acids rapidly induce the carnitine palmitoyltransferase I gene in the pancreatic beta-cell line INS-1.

21 January 2018

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Oxidized but not acetylated low-density lipoprotein reduces preproinsulin mRNA expression and secretion of insulin from HIT-T15 cells.

21 January 2018

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Cyclic Oscillations of Basal Plasma Glucose and Insulin Concentrations in Human Beings

21 January 2018

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Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes.

21 January 2018

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Abnormalities of insulin pulsatility and glucose oscillations during meals in obese noninsulin-dependent diabetic patients: effects of weight reduction

21 January 2018

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Disorganization of cytoplasmic Ca(2+) oscillations and pulsatile insulin secretion in islets from ob/ obmice

21 January 2018

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Connexin 36 controls synchronization of Ca2+ oscillations and insulin secretion in MIN6 cells.

21 January 2018

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Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release.

21 January 2018

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Cx36-mediated coupling reduces beta-cell heterogeneity, confines the stimulating glucose concentration range, and affects insulin release kinetics

21 January 2018

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Mechanisms of the stimulation of insulin release by saturated fatty acids. A study of palmitate effects in mouse beta-cells

21 January 2018

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Differential mechanisms of glucose and palmitate in augmentation of insulin secretion in mouse pancreatic islets

21 January 2018

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A fatty acid- dependent step is critically important for both glucose- and non-glucose-stimulated insulin secretion

21 January 2018

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Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR).

21 January 2018

1 reference

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Stimulation of acetyl-CoA carboxylase gene expression by glucose requires insulin release and sterol regulatory element binding protein 1c in pancreatic MIN6 beta-cells

21 January 2018

1 reference

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The transcription factor SREBP-1c is instrumental in the development of beta-cell dysfunction

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M708181200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18073214%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference