(Q40037021)

16 September 2017

Hsp90-inhibitor geldanamycin abrogates G2 arrest in p53-negative leukemia cell lines through the depletion of Chk1. (English)

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16 September 2017

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K Sugimoto

1

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16 September 2017

M Sasaki

2

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16 September 2017

Y Isobe

3

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16 September 2017

M Tsutsui

4

1 reference

16 September 2017

H Suto

5

1 reference

16 September 2017

J Ando

6

1 reference

16 September 2017

K Tamayose

7

1 reference

16 September 2017

M Ando

8

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16 September 2017

K Oshimi

9

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16 September 2017

language of work or name

English

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publication date

10 December 2007

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16 September 2017

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16 September 2017

27

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16 September 2017

22

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16 September 2017

3091-3101

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210978

16 September 2017

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cites work

Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Dual phosphorylation controls Cdc25 phosphatases and mitotic entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Enhanced tumor cell radiosensitivity and abrogation of G2 and S phase arrest by the Hsp90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Heat shock protein 90 regulates the metaphase-anaphase transition in a polo-like kinase-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

The human decatenation checkpoint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

The polo-like kinase Plx1 is required for M phase exit and destruction of mitotic regulators in Xenopus egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Cell cycle checkpoints: preventing an identity crisis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

BCR-ABL point mutants isolated from patients with imatinib mesylate-resistant chronic myeloid leukemia remain sensitive to inhibitors of the BCR-ABL chaperone heat shock protein 90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Geldanamycin and herbimycin A induce apoptotic killing of B chronic lymphocytic leukemia cells and augment the cells' sensitivity to cytotoxic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Phosphorylation of Bcl-2 is a marker of M phase events and not a determinant of apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Heat shock protein 90 inhibition sensitizes acute myelogenous leukemia cells to cytarabine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Selective apoptosis of tandemly duplicated FLT3-transformed leukemia cells by Hsp90 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Antimyeloma activity of heat shock protein-90 inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Hsp90 inhibitors as novel cancer chemotherapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

The G(2) checkpoint is maintained by redundant pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Structure, function, and mechanism of the Hsp90 molecular chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Low-dose doxorubicin-induced necrosis in Jurkat cells and its acceleration and conversion to apoptosis by antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Activation of an ataxia telangiectasia mutation-dependent intra-S-phase checkpoint by anti-tumour drugs in HL-60 and human lymphoblastoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Potentiation of cytotoxicity of topoisomerase i poison by concurrent and sequential treatment with the checkpoint inhibitor UCN-01 involves disparate mechanisms resulting in either p53-independent clonogenic suppression or p53-dependent mitotic cata

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

Structural basis for Chk1 inhibition by UCN-01

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

A role for Hsp90 in cell cycle control: Wee1 tyrosine kinase activity requires interaction with Hsp90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

inferred from DOI database lookup

7 January 2021

based on heuristic

A DNA damage checkpoint meets the cell cycle engine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

inferred from DOI database lookup

7 January 2021

based on heuristic

Selective radiosensitization of p53-deficient cells by caffeine-mediated activation of p34cdc2 kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210978

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1210978

1 reference

Dimensions Publication ID

16 September 2017

0 references

1 reference