(Q40037030)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071308%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

The FLT3 inhibitor PKC412 exerts differential cell cycle effects on leukemic cells depending on the presence of FLT3 mutations (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071308%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

7

1 reference

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29 December 2019

author name string

T Odgerel

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071308%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

J Kikuchi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071308%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

T Wada

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071308%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

R Shimizu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071308%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

K Futaki

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071308%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Y Kano

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071308%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

language of work or name

English

0 references

publication date

10 December 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071308%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071308%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

volume

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071308%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071308%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

page(s)

3102-3110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071308%20AND%20SRC:MED&resulttype=core&format=json

JNK phosphorylation and activation of BAD couples the stress-activated signaling pathway to the cell death machinery

29 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

Raf1 interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

The roles of FLT3 in hematopoiesis and leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

21 January 2018

At the gates of death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

FLT3 tyrosine kinase as a target in acute leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

Constitutively activated FLT3 phosphorylates BAD partially through pim-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

In vitro studies of a FLT3 inhibitor combined with chemotherapy: sequence of administration is important to achieve synergistic cytotoxic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

FLT3 tyrosine kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

Molecular cloning of a ligand for the flt3/flk-2 tyrosine kinase receptor: a proliferative factor for primitive hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

Distinct gene expression patterns associated with FLT3- and NRAS-activating mutations in acute myeloid leukemia with normal karyotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

FLT3 mutations in acute myeloid leukemia cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

Nuclear colocalization and interaction between bcl-xL and cdk1(cdc2) during G2/M cell-cycle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

The FLT3 internal tandem duplication mutation prevents apoptosis in interleukin-3-deprived BaF3 cells due to protein kinase A and ribosomal S6 kinase 1-mediated BAD phosphorylation at serine 112.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

Synergistic effect of SU11248 with cytarabine or daunorubicin on FLT3 ITD-positive leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

Divergent cytotoxic effects of PKC412 in combination with conventional antileukemic agents in FLT3 mutation-positive versus -negative leukemia cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

7 January 2021

Upgrading the BCL-2 network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

7 January 2021

Internal tandem duplication of FLT3 associated with leukocytosis in acute promyelocytic leukemia. Leukemia Study Group of the Ministry of Health and Welfare (Kohseisho)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

7 January 2021

Phase I and pharmacokinetic study of PKC412, an inhibitor of protein kinase C.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

7 January 2021

Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210980

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210980

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18071308%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 December 2019

1018505764

0 references

1 reference