(Q40041302)

English

Intracellular interaction of interleukin-15 with its receptor alpha during production leads to mutual stabilization and increased bioactivity

scientific article published on 30 November 2007

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scholarly article

1 reference

Europe PubMed Central

16 September 2017

Intracellular interaction of interleukin-15 with its receptor alpha during production leads to mutual stabilization and increased bioactivity (English)

1 reference

Europe PubMed Central

16 September 2017

author name string

Cristina Bergamaschi

1

1 reference

Europe PubMed Central

16 September 2017

Margherita Rosati

2

1 reference

Europe PubMed Central

16 September 2017

Rashmi Jalah

3

1 reference

Europe PubMed Central

16 September 2017

Antonio Valentin

4

1 reference

Europe PubMed Central

16 September 2017

Viraj Kulkarni

5

1 reference

Europe PubMed Central

16 September 2017

Candido Alicea

6

1 reference

Europe PubMed Central

16 September 2017

Gen-Mu Zhang

7

1 reference

Europe PubMed Central

16 September 2017

Vainav Patel

8

1 reference

Europe PubMed Central

16 September 2017

Barbara K Felber

9

1 reference

Europe PubMed Central

16 September 2017

George N Pavlakis

10

1 reference

Europe PubMed Central

16 September 2017

language of work or name

0 references

publication date

30 November 2007

1 reference

Europe PubMed Central

16 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

16 September 2017

283

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Europe PubMed Central

16 September 2017

7

1 reference

Europe PubMed Central

16 September 2017

4189-4199

1 reference

Europe PubMed Central

16 September 2017

Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor

1 reference

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21 January 2018

A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Natural, proteolytic release of a soluble form of human IL-15 receptor alpha-chain that behaves as a specific, high affinity IL-15 antagonist

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Combined IL-15/IL-15Ralpha immunotherapy maximizes IL-15 activity in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

IL-15R alpha expression on CD8+ T cells is dispensable for T cell memory

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Transregulation of memory CD8 T-cell proliferation by IL-15Rα+ bone marrow–derived cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Distinct cell types control lymphoid subset development by means of IL-15 and IL-15 receptor alpha expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

T cell-independent interleukin 15Ralpha signals are required for bystander proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Natural soluble interleukin-15Ralpha is generated by cleavage that involves the tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

IL-15/IL-15 receptor biology: a guided tour through an expanding universe

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Soluble Interleukin IL-15Ralpha is generated by alternative splicing or proteolytic cleavage and forms functional complexes with IL-15.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Mast Cells Express Novel Functional IL-15 Receptor α Isoforms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Natural splicing of exon 2 of human interleukin-15 receptor alpha-chain mRNA results in a shortened form with a distinct pattern of expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

IL-15: a pleiotropic cytokine with diverse receptor/signaling pathways whose expression is controlled at multiple levels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

DNA vaccines expressing different forms of simian immunodeficiency virus antigens decrease viremia upon SIVmac251 challenge

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Analysis of trafficking of Rev and transdominant Rev proteins in living cells using green fluorescent protein fusions: transdominant Rev blocks the export of Rev from the nucleus to the cytoplasm

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Dendritic cell-derived IL-15 controls the induction of CD8 T cell immune responses.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

IL-15 is superior to IL-2 in the generation of long-lived antigen specific memory CD4 and CD8 T cells in rhesus macaques

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Intravenous delivery of naked plasmid DNA for in vivo cytokine expression.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

IL-15 plays a major role in the persistence of Tax-specific CD8 cells in HAM/TSP patients

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

IFN regulatory factor 4 participates in the human T cell lymphotropic virus type I-mediated activation of the IL-15 receptor alpha promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

The IL-15/IL-15Ralpha on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 memory T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Interleukin (IL)-15Rα–deficient Natural Killer Cells Survive in Normal but Not IL-15Rα–deficient Mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Transporters of nucleotide sugars, ATP, and nucleotide sulfate in the endoplasmic reticulum and Golgi apparatus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

IL-15 induces CD4 effector memory T cell production and tissue emigration in nonhuman primates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Dendritic cells prime natural killer cells by trans-presenting interleukin 15

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705725200

21 January 2018

Identifiers

10.1074/JBC.M705725200

1 reference

Europe PubMed Central

16 September 2017

1 reference

Europe PubMed Central

16 September 2017

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