(Q40044913)

16 September 2017

The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation (English)

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16 September 2017

8

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16 September 2017

Yien Che Tsai

1

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16 September 2017

Arnulfo Mendoza

2

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16 September 2017

Jennifer M Mariano

3

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16 September 2017

Ming Zhou

4

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16 September 2017

Zlatka Kostova

5

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16 September 2017

Bo Chen

6

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16 September 2017

Timothy Veenstra

7

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16 September 2017

Lee J Helman

9

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16 September 2017

Chand Khanna

10

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16 September 2017

Allan M Weissman

11

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16 September 2017

language of work or name

English

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publication date

25 November 2007

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16 September 2017

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16 September 2017

13

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16 September 2017

1504-1509

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16 September 2017

12

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https://scigraph.springernature.com/pub.10.1038/nm1686

16 September 2017

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cites work

The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site

1 reference

The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum

21 January 2018

1 reference

Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78

21 January 2018

1 reference

Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase

21 January 2018

1 reference

Ubiquitin ligase gp78 increases solubility and facilitates degradation of the Z variant of alpha-1-antitrypsin

21 January 2018

1 reference

Overexpression of the tumor autocrine motility factor receptor Gp78, a ubiquitin protein ligase, results in increased ubiquitinylation and decreased secretion of apolipoprotein B100 in HepG2 cells

21 January 2018

1 reference

The autocrine motility factor receptor gene encodes a novel type of seven transmembrane protein

21 January 2018

1 reference

AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation

21 January 2018

1 reference

Metastasis suppression: the evolving role of metastasis suppressor genes for regulating cancer cell growth at the secondary site

21 January 2018

1 reference

The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis

21 January 2018

1 reference

CD82 metastasis suppressor gene: a potential target for new therapeutics?

21 January 2018

1 reference

Regulation of urokinase receptor proteolytic function by the tetraspanin CD82.

21 January 2018

1 reference

Tetraspanin CD82 regulates compartmentalisation and ligand-induced dimerization of EGFR.

21 January 2018

1 reference

Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression

21 January 2018

1 reference

Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein

21 January 2018

1 reference

Roles of sumoylation of a reptin chromatin-remodelling complex in cancer metastasis

21 January 2018

1 reference

Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes

21 January 2018

1 reference

KAI1 promoter activity is dependent on p53, junB and AP2: evidence for a possible mechanism underlying loss of KAI1 expression in cancer cells

21 January 2018

1 reference

Loss of expression and altered localization of KAI1 and CD9 protein are associated with epithelial ovarian cancer progression.

21 January 2018

1 reference

Expression of the cytoskeleton linker protein ezrin in human cancers

21 January 2018

1 reference

The metastasis suppressor gene C33/CD82/KAI1 induces apoptosis through reactive oxygen intermediates

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Absence of p53-dependent induction of the metastatic suppressor KAI1 gene after DNA damage

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Metastasis suppressor genes: from gene identification to protein function and regulation

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NM1686

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Dimensions Publication ID

16 September 2017

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1 reference