(Q40045511)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18035834%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

title

Benzothiepin-derived molecular scaffolds for estrogen receptor modulators: synthesis and antagonistic effects in breast cancer cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18035834%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

4

1 reference

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27 December 2019

Daniela M Zisterer

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18035834%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

David Lloyd

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18035834%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

author name string

Mary J Meegan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18035834%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Irene Barrett

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18035834%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Jochen Zimmermann

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18035834%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

publication date

1 October 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18035834%20AND%20SRC:MED&resulttype=core&format=json

Journal of Enzyme Inhibition and Medicinal Chemistry

27 December 2019

published in

1 reference

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27 December 2019

volume

22

1 reference

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27 December 2019

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18035834%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

page(s)

655-666

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18035834%20AND%20SRC:MED&resulttype=core&format=json

Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 1. Receptor interactions

27 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 2. Clinical considerations and new agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Estrogen Receptors as Therapeutic Targets in Breast Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Estrogen receptor beta--a new dimension in estrogen mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

The biological role of estrogen receptors alpha and beta in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Loss of ERbeta expression as a common step in estrogen-dependent tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Molecular basis of agonism and antagonism in the oestrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Structural insights into the mode of action of a pure antiestrogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Structural basis for an unexpected mode of SERM-mediated ER antagonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Scaffold hopping in de novo design. Ligand generation in the absence of receptor information.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

EM-652 (SCH 57068), a third generation SERM acting as pure antiestrogen in the mammary gland and endometrium

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Novel chromene-derived selective estrogen receptor modulators useful for alleviating hot flushes and vaginal dryness

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Estrogen receptor ligands. II. Discovery of benzoxathiins as potent, selective estrogen receptor alpha modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

A novel estrogen receptor ligand template

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

A selective estrogen receptor modulator for the treatment of hot flushes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Benzoxepin-derived estrogen receptor modulators: a novel molecular scaffold for the estrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Structure-Based drug design: synthesis, crystal structure, biological evaluation and docking studies of mono- and bis-benzo[ b ]oxepines as non-steroidal estrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Estrogen receptor transcription and transactivation: Estrogen receptor alpha and estrogen receptor beta: regulation by selective estrogen receptor modulators and importance in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

A simple and sensitive microtiter plate estrogen bioassay based on stimulation of alkaline phosphatase in Ishikawa cells: estrogenic action of delta 5 adrenal steroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Synthesis of 2-(p-chlorobenzyl)-3-aryl-6-methoxybenzofurans as selective ligands for antiestrogen-binding sites. Effects on cell proliferation and cholesterol synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Halogenated analogues of tamoxifen: synthesis, receptor assay, and inhibition of MCF7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Tricyclic triarylethylene antiestrogens: dibenz[b,f]oxepins, dibenzo[b,f]thiepins, dibenzo[a,e]cyclooctenes, and dibenzo[b,f]thiocins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Synthesis, structure-activity relationships and antagonistic effects in human MCF-7 breast cancer cells of flexible estrogen receptor modulators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Automated analysis of interatomic contacts in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

ERbeta ligands. 3. Exploiting two binding orientations of the 2-phenylnaphthalene scaffold to achieve ERbeta selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

ERbeta ligands. Part 2: Synthesis and structure-activity relationships of a series of 4-hydroxy-biphenyl-carbaldehyde oxime derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

Centchroman, a selective estrogen receptor modulator, as a contraceptive and for the management of hormone-related clinical disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360701503232

10.1080/14756360701503232

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18035834%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference