(Q40058260)

English

Phosphorylation of serine 68 in the IkappaB kinase (IKK)-binding domain of NEMO interferes with the structure of the IKK complex and tumor necrosis factor-alpha-induced NF-kappaB activity

scientific article published on 31 October 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Phosphorylation of serine 68 in the IkappaB kinase (IKK)-binding domain of NEMO interferes with the structure of the IKK complex and tumor necrosis factor-alpha-induced NF-kappaB activity (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

phosphorylation

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Lysann Palkowitsch

1

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Julia Leidner

2

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Sankar Ghosh

3

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Ralf B Marienfeld

4

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

language of work or name

0 references

publication date

31 October 2007

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

283

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

76-86

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Antigen-receptor signaling to nuclear factor kappa B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

NF-kappaB and the immune response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Signaling to NF-kappaB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Interleukin-1-induced NF-kappaB activation is NEMO-dependent but does not require IKKbeta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Mature T cells depend on signaling through the IKK complex.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kappaB activation by the human T-cell leukemia virus tax oncoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Sites on FIP-3 (NEMO/IKKgamma) essential for its phosphorylation and NF-kappaB modulating activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

In vivo identification of inducible phosphoacceptors in the IKKgamma/NEMO subunit of human IkappaB kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Detection of IKKbeta-IKKgamma subcomplexes in monocytic cells and characterization of associated signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

The zinc finger domain of NEMO is selectively required for NF-kappa B activation by UV radiation and topoisomerase inhibitors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Stimulation of IKK-gamma oligomerization by the human T-cell leukemia virus oncoprotein Tax.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

NEMO oligomerization in the dynamic assembly of the IkappaB kinase core complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Tetrameric oligomerization of IkappaB kinase gamma (IKKgamma) is obligatory for IKK complex activity and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Dimerization of the I kappa B kinase-binding domain of NEMO is required for tumor necrosis factor alpha-induced NF-kappa B activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Inhibition of NF-kappa B activation by peptides targeting NF-kappa B essential modulator (nemo) oligomerization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Characterization of the Ikappa B-kinase NEMO binding domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

RelB forms transcriptionally inactive complexes with RelA/p65.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

NEMO trimerizes through its coiled-coil C-terminal domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Regulation of Ikappa B kinase (IKK)gamma /NEMO function by IKKbeta -mediated phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Human T-lymphotropic virus type I tax activates I-kappa B kinase by inhibiting I-kappa B kinase-associated serine/threonine protein phosphatase 2A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Regulation of IkappaB kinase (IKK) complex by IKKgamma-dependent phosphorylation of the T-loop and C terminus of IKKbeta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

I kappa B kinase 2 deficiency in T cells leads to defects in priming, B cell help, germinal center reactions, and homeostatic expansion.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

IkappaB kinase alpha (IKKalpha) regulation of IKKbeta kinase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708856200

21 January 2018

Identifiers

10.1074/JBC.M708856200

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

release_vehbzye26vdnfk6kmx6qcvmuwe

1 reference

https://api.fatcat.wiki/v0/release/vehbzye26vdnfk6kmx6qcvmuwe

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

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