(Q40073191)

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Induction of endoplasmic reticulum stress-induced beta-cell apoptosis and accumulation of polyubiquitinated proteins by human islet amyloid polypeptide

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Europe PubMed Central

PubMed publication ID

17 September 2017

Induction of endoplasmic reticulum stress-induced beta-cell apoptosis and accumulation of polyubiquitinated proteins by human islet amyloid polypeptide (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

endoplasmic reticulum

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apoptotic process

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based on heuristic

inferred from title

author name string

Chang-Jiang Huang

1

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Leena Haataja

2

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Tatyana Gurlo

3

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Alexandra E Butler

4

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Xiuju Wu

5

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Walter C Soeller

6

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Peter C Butler

7

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

publication date

2 October 2007

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

American Journal of Physiology - Endocrinology and Metabolism

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Europe PubMed Central

PubMed publication ID

17 September 2017

293

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Europe PubMed Central

PubMed publication ID

17 September 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

E1656-62

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Increased beta-cell apoptosis prevents adaptive increase in beta-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Impairment of the ubiquitin-proteasome pathway is a downstream endoplasmic reticulum stress response induced by extracellular human islet amyloid polypeptide and contributes to pancreatic beta-cell apoptosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Atomic force microscopy reveals defects within mica supported lipid bilayers induced by the amyloidogenic human amylin peptide.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

High white blood cell count is associated with a worsening of insulin sensitivity and predicts the development of type 2 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

The aggregation potential of human amylin determines its cytotoxicity towards islet beta-cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Neurodegenerative disease: amyloid pores from pathogenic mutations

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Toxic human islet amyloid polypeptide (h-IAPP) oligomers are intracellular, and vaccination to induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced beta-cell apoptosis in h-IAPP transgenic mice

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Beta-cell deficit due to increased apoptosis in the human islet amyloid polypeptide transgenic (HIP) rat recapitulates the metabolic defects present in type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Inhibition of human IAPP fibril formation does not prevent beta-cell death: evidence for distinct actions of oligomers and fibrils of human IAPP.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Ubiquitin is a component of paired helical filaments in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Islet amyloid polypeptide in human insulinomas. Evidence for intracellular amyloidogenesis

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Islet amyloid polypeptide: a review of its biology and potential roles in the pathogenesis of diabetes mellitus

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Replication increases beta-cell vulnerability to human islet amyloid polypeptide-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Amylin-induced cytotoxicity is associated with activation of caspase-3 and MAP kinases

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Islet amyloid-associated diabetes in obese A(vy)/a mice expressing human islet amyloid polypeptide.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Fibrillogenic amylin evokes islet beta-cell apoptosis through linked activation of a caspase cascade and JNK1.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Induction of apoptosis by human amylin in RINm5F islet beta-cells is associated with enhanced expression of p53 and p21WAF1/CIP1.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00318.2007

21 January 2018

Identifiers

10.1152/AJPENDO.00318.2007

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

ResearchGate publication ID

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