(Q40082894)

English

Histone deacetylase inhibitor apicidin downregulates DNA methyltransferase 1 expression and induces repressive histone modifications via recruitment of corepressor complex to promoter region in human cervix cancer cells

scientific article published on 10 September 2007

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scholarly article

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Europe PubMed Central

PubMed publication ID

17 September 2017

Histone deacetylase inhibitor apicidin downregulates DNA methyltransferase 1 expression and induces repressive histone modifications via recruitment of corepressor complex to promoter region in human cervix cancer cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

9

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17 September 2017

author name string

You JS

1

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17 September 2017

Kang JK

2

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17 September 2017

Lee EK

3

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Europe PubMed Central

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17 September 2017

Lee JC

4

1 reference

Europe PubMed Central

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17 September 2017

Lee SH

5

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Europe PubMed Central

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17 September 2017

Jeon YJ

6

1 reference

Europe PubMed Central

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17 September 2017

Koh DH

7

1 reference

Europe PubMed Central

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17 September 2017

Ahn SH

8

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Lee HY

10

1 reference

Europe PubMed Central

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17 September 2017

Cho EJ

11

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17 September 2017

Han JW

12

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17 September 2017

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publication date

10 September 2007

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17 September 2017

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Europe PubMed Central

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17 September 2017

27

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Europe PubMed Central

PubMed publication ID

17 September 2017

10

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Europe PubMed Central

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17 September 2017

1376-1386

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Europe PubMed Central

PubMed publication ID

17 September 2017

Role of DNA 5-methylcytosine transferase in cell transformation by fos

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Role of DNA methylation in the regulation of transcription

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Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways

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Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1

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Translating the Histone Code

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Chromatin modifications and their function

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Apicidin, a histone deacetylase inhibitor, induces apoptosis and Fas/Fas ligand expression in human acute promyelocytic leukemia cells

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Suppression of intestinal neoplasia by DNA hypomethylation.

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Procainamide is a specific inhibitor of DNA methyltransferase 1.

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A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

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The role of chromatin during transcription

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Somatic mutations in the neurofibromatosis 1 gene in human tumors

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A profile of methyl-CpG binding domain protein occupancy of hypermethylated promoter CpG islands of tumor suppressor genes in human cancer

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Retinoblastoma protein represses transcription by recruiting a histone deacetylase

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Histone deacetylases and cancer: causes and therapies

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Examination of a CpG island methylator phenotype and implications of methylation profiles in solid tumors

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21 January 2018

Regulation of E2F1 activity by acetylation

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21 January 2018

Regulation of DNA methyltransferase 1 by the pRb/E2F1 pathway

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21 January 2018

Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer

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21 January 2018

Human polyomavirus BKV transcriptionally activates DNA methyltransferase 1 through the pRb/E2F pathway

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21 January 2018

DNA methyltransferase inhibition induces the transcription of the tumor suppressor p21(WAF1/CIP1/sdi1).

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Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

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Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

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Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation

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Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53.

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Epigenetic reprogramming in mammalian development

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DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells

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The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

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DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

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Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter

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Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells.

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Identifiers

10.1038/SJ.ONC.1210776

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

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