(Q40084496)

17 September 2017

1 reference

title

Clinical implications of enzyme induction and enzyme inhibition (English)

1 reference

17 September 2017

Clinical Implications of Enzyme Induction and Enzyme Inhibition (English)

1 reference

10.2165/00003088-198106010-00001

Crossref

DOI

https://api.crossref.org/works/10.2165/00003088-198106010-00001

7 August 2023

1 reference

10.2165/00003088-198106010-00001

https://api.crossref.org/works/10.2165/00003088-198106010-00001

7 August 2023

author name string

B. K. Park

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6113907

7 August 2023

A. M. Breckenridge

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6113907

7 August 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=6113907

7 August 2023

publication date

1 January 1981

1 reference

Clinical Pharmacokinetics

17 September 2017

1 reference

17 September 2017

6

1 reference

17 September 2017

1-24

1 reference

17 September 2017

1

1 reference

https://scigraph.springernature.com/pub.10.2165/00003088-198106010-00001

17 September 2017

0 references

cites work

Oral Anticoagulants-Their Interactions

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12 December 2020

Effect of diphenylhydantoin on cortisol kinetics in humans

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12 December 2020

THE ROLE OF GAMMA-GLUTAMYL TRANSPEPTIDASE IN THE INTERNAL DISEASES CLINIC

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12 December 2020

Megaloblastic anaemia in anticonvulsant therapy

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12 December 2020

Studies on the different metabolic pathways of antipyrine in man. I. Oral administration of 250, 500 and 1000 mg to healthy volunteers

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12 December 2020

The antipyrine test in clinical pharmacology: Conceptions and misconceptions

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12 December 2020

Antibacterial activity in serum and urine following oral administration in man of DL473 (a cyclopentyl derivative of rifampicin) [proceedings]

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12 December 2020

6beta-Hydroxycortisol and other polar corticosteroids: measurement and significance in human urine

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12 December 2020

Mechanism of induction of hepatic microsomal drug metabolizing enzymes by a series of barbiturates

1 reference

12 December 2020

Induction of hepatic microsomal enzymes after brief administration of rifampicin in man

1 reference

12 December 2020

Effect of diphenylhydantoin on the metabolism of dicoumarol in man.

1 reference

12 December 2020

A pharmacokinetic interaction in man between phenobarbitone and fenoprofen, a new anti-inflammatory agent

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12 December 2020

[Effects of rifampicin on the menstrual cycle and on oestrogen excretion in patients taking oral contraceptives]

1 reference

12 December 2020

Methaqualone pharmacokinetics after single- and multiple-dose administration in man.

1 reference

12 December 2020

Psychotropic drugs (2). Interaction between monoamine oxidase (MAO) inhibitors and other substances.

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12 December 2020

D-glucaric-acid excretion as a test for hepatic enzyme induction.

1 reference

12 December 2020

Stimulation of drug metabolism in man by tricyclic antidepressants

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12 December 2020

Interactions between digitoxin and other drugs in vitro and in vivo

1 reference

12 December 2020

1 reference

12 December 2020

Inhibition of drug metabolism by acute ethanol intoxication. A hepatic microsomal mechanism

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12 December 2020

Changes of the smooth endoplasmic reticulum induced by rifampicin in human and guinea-pig hepatocytes

1 reference

12 December 2020

AN EFFECT OF O,P'-DDD ON THE EXTRA-ADRENAL METABOLISM OF CORTISOL IN MAN.

1 reference

12 December 2020

Antipyrine: radioimmunoassay in plasma and saliva following administration of a high dose and a low dose

1 reference

12 December 2020

Kinetic studies on rifampicin. I. Serum concentration analysis in subjects treated with different oral doses over a period of two weeks

1 reference

12 December 2020

The effect of phenobarbital on plasma diphenylhydantoin level and metabolism in man and in rat liver microsomes

1 reference

12 December 2020

Effect of vitamin C supplement on antipyrine disposition in man.

1 reference

12 December 2020

Increased rate of tolbutamide metabolism in alcoholic patients

1 reference

12 December 2020

[Reduction of the blood level of rifampicin by phenobarbital]

1 reference

12 December 2020

Osteomalacia with Long-term Anticonvulsant Therapy in Epilepsy

1 reference

12 December 2020

Drug induced changes of the blood glucose lowering effect of oral hypoglycemic agents

1 reference

12 December 2020

Effect of intensive occupational exposure to DDT on phenylbutazone and cortisol metabolism in human subiects

1 reference

12 December 2020

EFFECT OF DIPHENYLHYDANTOIN ON CORTISOL METABOLISM IN MAN.

1 reference

12 December 2020

Effect of diphenylhydantoin on hepatic drug hydroxylation

1 reference

12 December 2020

The effect of enzyme induction on the irreversible binding of ethynyloestradiol to guinea pig liver microsomes

1 reference

12 December 2020

Phenobarbitone effects on hepatic microsomal enzymes and liver blood flow in the guinea pig

1 reference

12 December 2020

Enzyme induction (first of three parts)

1 reference

12 December 2020

Effect of cigarette smoking on phenacetin metabolism

1 reference

12 December 2020

Neonatal coagulation defect due to anticonvulsant drug treatment in pregnancy.

1 reference

12 December 2020

Letter: Rifampicin and drug metabolism

1 reference

12 December 2020

Mechanism of folate deficiency in patients receiving phenytoin

1 reference

12 December 2020

Interaction of sodium warfarin and rifampin. Studies in man.

1 reference

12 December 2020

Blood Levels of Drug at the Equilibrium State after Multiple Dosing

1 reference

12 December 2020

[The influence of rifampicin therapy on oral anticoagulation with acenocoumarol]

1 reference

12 December 2020

Cytochrome P-450-mediated oxidation of 2-hydroxyestrogens to reactive intermediates

1 reference

12 December 2020

Salivary antipyrine half-life: a useful measure of hepatic drug metabolism

1 reference

12 December 2020

Changes in cortisol metabolism following rifampicin therapy

1 reference

12 December 2020

Evaluation ofin vivo parameters of drug metabolizing enzyme activity in man after administration of clemastine, phenobarbital or placebo

1 reference

12 December 2020

Inhibition of drug metabolism in man.

1 reference

12 December 2020

Stimulatory effect of brussels sprouts and cabbage on human drug metabolism

1 reference

12 December 2020

Biochemical and genetic factors regulating dilantin metabolism in man.

1 reference

12 December 2020

Urinary D-glucaric-acid excretion as a test for hepatic enzyme induction in man

1 reference

12 December 2020

Plasma gamma-glutamyl transpeptidase elevation in patients receiving enzyme-inducing drugs

1 reference

12 December 2020

[Activity of benzopyrene hydrolase in human liver-biopsy specimens in vitro and its relationship to the elimination speed of glycodiazine in vivo]

1 reference

12 December 2020

Interaction between Doxycycline and some Antiepileptic Drugs

1 reference

12 December 2020

Liver Function in Workers Having High Tissue Stores of Chlorinated Hydrocarbon Pesticides

1 reference

12 December 2020

Differential effects of hepatic microsomal enzyme inducing agents on liver blood flow

1 reference

12 December 2020

Effect of phenobarbital and glutethimide on biological half-life of warfarin

1 reference

12 December 2020

Interaction of rifampicin treatment with pharmacokinetics and metabolism of ethinyloestradiol in man

1 reference

12 December 2020

Effect of butabarbital on orally administered anticoagulants.

1 reference

12 December 2020

The effect of rifampicin on dapsone metabolism

1 reference

12 December 2020

Effect of chronic anticonvulsant therapy on serum 25-hydroxycalciferol levels in adults

1 reference

12 December 2020

Induction of hepatic microsomal hydroxylating enzymes by technical piperonyl butoxide and some of its analogs

1 reference

12 December 2020

Clinical implications of enzyme induction

1 reference

12 December 2020

The features of hepatic enzyme induction with glutethimide in man

1 reference

12 December 2020

The Effect of Spironolactone on Antipyrine Metabolism in Man

1 reference

12 December 2020

Inhibition of drug metabolism. IV. Induction of drug metabolism by 2-diethylaminoethyl 2,2-diphenylvalerate HC1 (SKF 525-A) and 2,4-dichloro-6-phenylphenoxyethylamine HBr (Lilly 18947) and the effect of induction on the inhibitory properties of SKF

1 reference

12 December 2020

Acute Stimulation of Cortisol Metabolism by Pentobarbital in Man

1 reference

12 December 2020

Cimetidine potentiates the anticoagulant effect of warfarin by inhibition of drug metabolism

1 reference

12 December 2020

Megaloblastic anaemia due to phenytoin sodium

1 reference

12 December 2020

[The effects of antituberculosis drugs on the pharmacokinetics of digitoxin (author's transl)]

1 reference

12 December 2020

Increased clearance of antipyrine and d-propranolol after phenobarbital treatment in the monkey. Relative contributions of enzyme induction and increased hepatic blood flow

1 reference

12 December 2020

Effect of phenobarbitone on plasma (14C)bilirubin clearance in patients with unconjugated hyperbilirubinaemia.

1 reference

12 December 2020

Interindividual differences in drug oxidation: clinical importance.

1 reference

12 December 2020

Commentary: a physiological approach to hepatic drug clearance

1 reference

12 December 2020

The metabolic fate of tolbutamide in man and in the rat

1 reference

12 December 2020

Genetic Control of Phenylbutazone Metabolism in Man

1 reference

12 December 2020

A direct radioimmunoassay for 6 beta-hydroxycortisol in human urine

1 reference

12 December 2020

Cimetidine: interaction with oral anticoagulants in man

1 reference

12 December 2020

SULPHAPHENAZOLE-INDUCED HYPOGLYCAEMIC ATTACKS IN TOLBUTAMIDE-TREATED DIABETICS

1 reference

12 December 2020

Dose-dependent enzyme induction

1 reference

12 December 2020

Multicompartmental analysis of serum, urine and bile concentrations of rifampicin and desacetyl-rifampicin in subjects treated for one week

1 reference

12 December 2020

Diphenylhydantoin intoxication. A complication of isoniazid therapy

1 reference

12 December 2020

Effect of environmental factors on drug metabolism: Decreased plasma half-life of antipyrine in workers exposed to chlorinated hydrocarbon insecticides

1 reference

12 December 2020

Induction of microsomal enzyme synthesis by polycyclic aromatic hydrocarbons of different molecular sizes

1 reference

12 December 2020

The rate of decline of diphenylhydantoin in human plasma

1 reference

12 December 2020

Role of tobacco smoking in pharmacokinetics

1 reference

12 December 2020

Metabolic alterations produced in the liver by chronic ethanol administration. Increased oxidative capacity

1 reference

12 December 2020

Carbamazepine-induced acceleration of diphenylhydantoin and warfarin metabolism in man

1 reference

12 December 2020

The effect of diphenylhydantoin on thyroxine metabolism in man.

1 reference

12 December 2020

Apparent resistance to oral anticoagulant therapy and influence of hypnotics on some coagulation factors.

1 reference

12 December 2020

Failure of 2 h [14C]-aminopyrine breath test to demonstrate microsomal enzyme induction by glutethimide [proceedings]

1 reference

12 December 2020

The influence of barbiturates on coumarin plasma levels and prothrombin response

1 reference

12 December 2020

Cortisol production in epileptic patients treated with diphenylhydantoin

1 reference

12 December 2020

Phenobarbitone-induced urinary excretions of D-glucaric acid and 6beta-hydroxycortisol in man

1 reference

12 December 2020

Drug Interactions with Warfarin: Studies with Dichloralphenazone, Chloral Hydrate and Phenazone (Antipyrine)

1 reference

12 December 2020

PHENOBARBITAL-INDUCED INCREASE IN 6-BETA-HYDROXYCORTISOL EXCRETION: CLUE TO ITS SIGNIFICANCE IN HUMAN URINE

1 reference

12 December 2020

Factors influencing antipyrine elimination

1 reference

12 December 2020

AN EFFECT OF PHENOBARBITONE ON BLOOD-LEVELS OF GRISEOFULVIN IN MAN

1 reference

12 December 2020

Time-course of interaction between carbamazepine and clonazepam in normal man

1 reference

12 December 2020

Rimactan (rifampicin) and anticoagulant therapy

1 reference

12 December 2020

THE BIOCHEMICAL INTERPRETATION OF HYPNOTIC ADDICTION

1 reference

12 December 2020

Drug Interactions with Oral Sulphonylurea Hypoglycaemic Drugs

1 reference

12 December 2020

Developmental effects on liver D-glucuronolactone dehydrogenase levels and on D-glucaric acid excretion in urine; hormonal effects on D-glucaric acid excretion in urine.

1 reference

12 December 2020

Plasma levels of monomethylated tricyclic antidepressants during treatment with imipramine-like compounds

1 reference

12 December 2020

The effect of rifampicin on norethisterone pharmacokinetics

1 reference

12 December 2020

Influence of rifampicin on drug metabolism: differences between hexobarbital and antipyrine

1 reference

12 December 2020

Effect of diphenylhydantoin on the metabolism of dexamethasone

1 reference

12 December 2020

Metabolism of d-glucuronolactone in mammalian systems. Identification of d-glucaric acid as a normal constituent of urine

1 reference

12 December 2020

Impairment of human drug metabolism by oral contraceptive steroids.

1 reference

12 December 2020

Antipyrine as an in vitro probe of mixed function oxidase activity [proceeding]

1 reference

12 December 2020

Folate Deficiency after Anticonvulsant Drugs: An Effect of Hepatic Enzyme Induction?

1 reference

12 December 2020

Drug‐metabolizing capacity in states of drug dependence and withdrawal

1 reference

12 December 2020

Liver size and indices of drug metabolism in epileptics

1 reference

12 December 2020

Effect of N-phenylbarbital (phetharbital) on the metabolism of testosterone and cortisol in man

1 reference

12 December 2020

Influence of age and smoking on drug kinetics in man: studies using model compounds

1 reference

12 December 2020

A soluble form of gamma-glutamyl transpeptidase in human tissues

1 reference

12 December 2020

Changes in plasma -glutamyl transpeptidase activity associated with alterations in drug metabolism in man.

1 reference

12 December 2020

Pharmacological implications of microsomal enzyme induction.

1 reference

12 December 2020

Blood levels of diazepam (Valium) and N-desmethyl diazepam in the epileptic child. A preliminary report

1 reference

12 December 2020

Changes in D-glucaric acid excretion in relationship to alterations in the rate of antipyrine metabolism in man.

1 reference

12 December 2020

Interaction between Doxycycline and Barbiturates

1 reference

12 December 2020

Effect of some drugs on lactonase activity of rat liver

1 reference

12 December 2020

[Enzyme induction by drugs and hormonal contraception]

1 reference

12 December 2020

Serum concentrations and biliary excretion of bilirubin during short-term treatment with rifampicin

1 reference

12 December 2020

Clinical Observations of Possible Barbiturate Interference With Anticoagulation

1 reference

12 December 2020

Urinary D-glucaric acid. An index of heparin microsomal enzyme activity in human females

1 reference

12 December 2020

Interactions between digitoxin and other drugs in man

1 reference

12 December 2020

Induction of drug metabolism in man after rifampicin treatment measured by increased hexobarbital and tolbutamide clearance

1 reference

12 December 2020

Modification of chlorpromazine metabolism by some other drugs frequently administered to psychiatric patients.

1 reference

12 December 2020

Urinary D-glucaric acid excretion and total liver content of cytochrome P-450 in guinea-pigs: Relationship during enzyme induction and following inhibition of protein synthesis

1 reference

12 December 2020

The effects of chronic drug administration on hepatic enzyme induction and folate metabolism

1 reference

12 December 2020

Serum γ-glutamyl transpeptidase activity in alcoholism

1 reference

12 December 2020

Effect of charcoal-broiled beef on antipyrine and theophylline metabolism

1 reference

12 December 2020

Genetic control of the phenobarbital-induced shortening of plasma antipyrine half-lives in man.

1 reference

12 December 2020

Treatment of Gilbert's syndrome with phenobarbitone.

1 reference

12 December 2020

The effect of diet and phenobarbitone on quinine metabolism in the rat and in man

1 reference

12 December 2020

Metabolism of nitroglycerin in man: influence of phenobarbital

1 reference

12 December 2020

Rifampicin and vitamin D metabolism

1 reference

12 December 2020

The effect of enzyme induction on diazepam metabolism in man

1 reference

12 December 2020

Warfarin. Stereochemical aspects of its metabolism and the interaction with phenylbutazone

1 reference

12 December 2020

Influence of dietary protein and carbohydrate on antipyrine and theophylline metabolism in man

1 reference

12 December 2020

Enzyme induction by oral testosterone

1 reference

12 December 2020

The effect of some sedatives (phenobarbital, gluthetimide, chlordiazepoxide, chloral hydrate) on the rate of disappearance of ethyl biscoumacetate from the plasma

1 reference

12 December 2020

DRUG INTERACTIONS IN MAN. I. LOWERING EFFECT OF PHENOBARBITAL ON PLASMA LEVELS OF BISHYDROXYCOUMARIN (DICUMAROL) AND DIPHENYLHYDANTOIN (DILANTIN)

1 reference

12 December 2020

Effect of rifampicin.treatment on the metabolism of oestradiol and 17?-ethinyloestradiol by human liver microsomes

1 reference

12 December 2020

Measurement of urinary 6-?-hydroxycortisol excretion as an in vivo parameter in the clinical assessment of the microsomal enzyme-inducing capacity of antipyrine, phenobarbitone and rifampicin

1 reference

12 December 2020

Evidence for the Clara cell as a site of cytochrome P450-dependent mixed-function oxidase activity in lung

1 reference

12 December 2020

The concentrations of diazepam and its metabolites in the plasma after an acute and chronic administration

1 reference

12 December 2020

Urinary excretion of 6 beta-hydroxycortisol in states of altered thyroid function

1 reference

12 December 2020

10.2165/00003088-198106010-00001

Identifiers

DOI

1 reference

Dimensions Publication ID

17 September 2017

0 references

1 reference