(Q40088896)

17 September 2017

1 reference

title

Molecular conformation and biological activity of central nervous system active drugs (English)

1 reference

17 September 2017

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

10 August 2023

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

10 August 2023

author name string

P. R. Andrews

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6129361

10 August 2023

E. J. Lloyd

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6129361

10 August 2023

language of work or name

1 reference

1 October 1982

1 reference

full work available at URL

17 September 2017

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fmed.2610020404

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

https://onlinelibrary.wiley.com/doi/full/10.1002/med.2610020404

10 August 2023

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Medicinal Research Reviews

10 August 2023

published in

1 reference

17 September 2017

volume

2

1 reference

17 September 2017

issue

4

1 reference

17 September 2017

page(s)

355-393

1 reference

A crystallographic and theoretical study of the conformation of DOET and its significance for the hallucinogenic amphetamines

17 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FMED.2610020404

The crystal structures of two polymorphs of 5-ethyl-5-isoamylbarbituric acid (amobarbital)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMED.2610020404

Minireview A systematic study of the pharmacological activities of dopamine antagonists

21 January 2018

14

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

The structure of the catecholamines. II. The crystal structure of dopamine hydrochloride

10 August 2023

15

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Conformational analysis of dopamine by the INDO molecular orbital method

10 August 2023

17

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Description of steric relationships across single bonds

10 August 2023

18

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Conformation of dopamine at the dopamine receptor

10 August 2023

19

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Chlorpromazie and Dopamine: Conformational Similarities that Correlate with the Antischizophrenic Activity of Phenothiazine Drugs

10 August 2023

20

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

2-Amino-6,7-dihydroxytetrahydronaphthalene and the receptor-site preferred conformation of dopamine—a commentary

10 August 2023

22

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Multiple receptors for dopamine

10 August 2023

23

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

10 August 2023

24

16

729

Camerman

1979

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Bicyclic and tricyclic ergoline partial structures. Rigid 3-(2-aminoethyl)pyrroles and 3- and 4-(2-aminoethyl)pyrazoles as dopamine agonists

10 August 2023

25

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

10 August 2023

27

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Dopamine receptor model and its application in the design of a new class of rigid pyrrolo[2,3-g]isoquinoline antipsychotics

10 August 2023

28

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

10 August 2023

Molecular Pharmaceutics

30

17

38

Harbert

1980

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Antidepressant and antipsychotic agents

10 August 2023

31

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Possible pharmacological and theoretical implications of x-ray structure of the tricyclic antidepressant imipramine.

10 August 2023

32

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Conformationally restricted tricyclic antidepressants. 1. Octahydrodibenzazepinonaphthyridines as rigid imipramine analogs

10 August 2023

34

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

10 August 2023

35

14

596

de Paulis

1978

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Inhibition of neuronal uptake of 3H-biogenic amines into rat cerebral cortex by partially and fully saturated derivatives of imipramine and desipramine. The importance of the aromatic ring in adrenergic amines--part 3

10 August 2023

37

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

10 August 2023

41

9

23

Baker

1973

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Quantum mechanical study of the conformational properties of phenethylamines of biochemical and medicinal interest

10 August 2023

44

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Conformation energies and electronic structure of phenethylamine and amphetamine

10 August 2023

46

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Conformational studies of amphetamine and medicinally important derivatives by nuclear magnetic resonance spectroscopy

10 August 2023

48

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Analysis of NMR Spectra for Rotamer Populations of Dimethoxyamphetamines

10 August 2023

49

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Pronounced pharmacological differences arising from minor structural changes in conformationally defined amphetamine analogues. Comparative evaluation of endo- and exo-2-amino- and endo- and exo-2-(methylamino)benzobicyclo[2.2.1]heptene and -benzobi

10 August 2023

53

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Conformationally rigid amphetamine analogs as inhibitors of monoamine uptake by brain synaptosomes

10 August 2023

54

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

10 August 2023

59

9

640

Kang

1973

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Conformational energy differences between side chain alkylated analogues of the hallucinogen 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane

10 August 2023

60

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

10 August 2023

65

16

729

Camerman

1979

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

On the conformations of hallucinogenic molecules and their correlation

10 August 2023

66

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

LSD and phenethylamine hallucinogens: new structural analogy and implications for receptor geometry

10 August 2023

67

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

The mechanism(s) of action of the benzodiazepines

10 August 2023

69

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Molecular orbital calculations on anticonvulsant drugs

10 August 2023

70

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Enthalpies of Hydrogen Bonding in Psychotropic Drugs

10 August 2023

71

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Association of CNS active drugs with 9-ethyladenine

10 August 2023

72

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Journal of Pharmacology and Experimental Therapeutics

10 August 2023

73

175

692

Downes

1970

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Inhibitors of GABA metabolism

10 August 2023

74

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

GABA agonists and antagonists

10 August 2023

75

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

A new class of GABA agonist

10 August 2023

76

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Conformational analysis of muscimol, a GABA agonist

10 August 2023

77

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Autoradiographic localization of benzodiazepine receptors in immunocytochemically identified gamma-aminobutyrergic synapses

10 August 2023

81

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Interaction of depressant, convulsant, and anticonvulsant barbiturates with the [3H]diazepam binding site of the benzodiazepine-GABA-receptor-ionophore complex.

10 August 2023

83

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Stereochemical basis of anticonvulsant drug action. II. Molecular structure of diazepam

10 August 2023

85

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Diphenylhydantoin and Diazepam: Molecular Structure Similarities and Steric Basis of Anticonvulsant Activity

10 August 2023

86

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

10 August 2023

87

7

406

Camerman

1971

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

The stereochemical basis of anticonvulsant drug action. IV. The crystal and molecular structure of trihexyphenidyl

10 August 2023

88

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Ethylphenacemide and phenacemide: conformational similarities to diphenylhydantoin and stereochemical basis of anticonvulsant activity

10 August 2023

90

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Stereochemical basis of anticonvulsant drug action. VI. Crystal and molecular structure of diphenylsilanediol

10 August 2023

91

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Common stereochemical features in anti-epileptic drugs: a reinvestigation

10 August 2023

94

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Molecular orbital calculations on the structure of the barbiturate receptor (author's transl)

10 August 2023

97

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

A molecular orbital study of the conformation of barbiturates

10 August 2023

98

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Convulsant and anticonvulsant barbiturates. 1. Molecular conformations from classical potential-energy calculations

10 August 2023

100

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Quinazolines and 1,4-benzodiazepines. 64. Comparison of the stereochemistry of diazepam with that of close analogs with marginal biological activity.

10 August 2023

101

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Parabolic dependence of drug action upon lipophilic character as revealed by a study of hypnotics

10 August 2023

116

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Is there a general anesthesia receptor

10 August 2023

117

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Optical isomerism and pharmacological action, a generalization

10 August 2023

119

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

10 August 2023

120

18

214

Trevor

1976

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Convulsant, anticonvulsant and anaesthetic barbiturates. 5-Ethyl-5-(3′-methyl-but-2′-enyl)-barbituric acid and related compounds

10 August 2023

123

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

The enkephalins and opiates: structure-activity relations

10 August 2023

124

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Synthetic analgesics: stereochemical considerations

10 August 2023

126

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Stereochemical studies on medicinal agents. 20. Absolute configuration and analgetic potency alpha-promedol enantiomers. The role of the C-4 chiral center in conferring stereoselectivity in axial- and equatorial-phenyl prodine congeners

10 August 2023

128

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

The opiate receptor: a model explaining structure-activity relationships of opiate agonists and antagonists

10 August 2023

129

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Proposal for the biologically active conformation of opiates and enkephalin

10 August 2023

130

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

Quantum chemical studies of morphine-like opiate narcotics. Effect of N-substituent variations

10 August 2023

131

1 reference

https://api.crossref.org/works/10.1002/MED.2610020404

10 August 2023

Identifiers

1 reference

17 September 2017

1 reference