(Q40095421)

English

Autophagic cell death, polyploidy and senescence induced in breast tumor cells by the substituted pyrrole JG-03-14, a novel microtubule poison

scientific article published on 7 July 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

Autophagic cell death, polyploidy and senescence induced in breast tumor cells by the substituted pyrrole JG-03-14, a novel microtubule poison (English)

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

0 references

breast neoplasm

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Christopher R Arthur

1

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

John T Gupton

2

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

Glen E Kellogg

3

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

W Andrew Yeudall

4

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

Myles C Cabot

5

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

Irene F Newsham

6

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

David A Gewirtz

7

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

language of work or name

0 references

publication date

7 July 2007

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

Biochemical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

74

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

7

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

981-991

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

22 September 2017

p53, Autophagy and tumor suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

22 September 2017

A case study in misidentification of cancer cell lines: MCF-7/AdrR cells (re-designated NCI/ADR-RES) are derived from OVCAR-8 human ovarian carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

22 September 2017

p53-Dependent accelerated senescence induced by ionizing radiation in breast tumour cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

22 September 2017

Evasion of a single-step, chemotherapy-induced senescence in breast cancer cells: implications for treatment response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

22 September 2017

The microtubule stabilizing agent discodermolide is a potent inducer of accelerated cell senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

22 September 2017

Potentiation of cell killing by fractionated radiation and suppression of proliferative recovery in MCF-7 breast tumor cells by the Vitamin D3 analog EB 1089.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

22 September 2017

Different spindle checkpoint proteins monitor microtubule attachment and tension at kinetochores in Drosophila cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

22 September 2017

A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

22 September 2017

Reconstitution of caspase 3 sensitizes MCF-7 breast cancer cells to doxorubicin- and etoposide-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

22 September 2017

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

22 September 2017

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

22 September 2017

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

22 September 2017

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

22 September 2017

Alteration of caspase-3 (CPP32/Yama/apopain) in wild-type MCF-7, breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

25 September 2017

p53 mutations do not predict response to paclitaxel/radiation for nonsmall cell lung carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

25 September 2017

Inactivation of p53 in a human ovarian cancer cell line increases the sensitivity to paclitaxel by inducing G2/M arrest and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

25 September 2017

Taxol-mediated augmentation of CD95 ligand-induced apoptosis of human malignant glioma cells: association with bcl-2 phosphorylation but neither activation of p53 nor G2/M cell cycle arrest

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

25 September 2017

Growth arrest and non-apoptotic cell death associated with the suppression of c-myc expression in MCF-7 breast tumor cells following acute exposure to doxorubicin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

25 September 2017

Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

25 September 2017

Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

17 June 2018

Characterization of adriamycin-resistant human breast cancer cells which display overexpression of a novel resistance-related membrane protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

17 June 2018

Potentiation of radiation sensitivity in breast tumor cells by the vitamin D3 analogue, EB 1089, through promotion of autophagy and interference with proliferative recovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

20 August 2018

Synthesis and cytotoxicity of substituted ethyl 2-phenacyl-3-phenylpyrrole-4-carboxylates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

20 August 2018

Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

20 August 2018

Adriamycin-induced senescence in breast tumor cells involves functional p53 and telomere dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

20 August 2018

The cytotoxicity and mode of action of 2,3,4-trisubstituted pyrroles and related derivatives in human Tmolt4 leukemia cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

20 August 2018

Combretastatin A-4 phosphate as a tumor vascular-targeting agent: early effects in tumors and normal tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

20 August 2018

Induction of differentiation and growth arrest associated with nascent (nonoligosomal) DNA fragmentation and reduced c-myc expression in MCF-7 human breast tumor cells after continuous exposure to a sublethal concentration of doxorubicin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

20 August 2018

Cisplatin, camptothecin, and taxol sensitivities of cells with p53-associated multidrug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000298

2 December 2018

Synthesis and cytotoxicity of 2,4-disubstituted and 2,3,4-trisubstituted brominated pyrroles in murine and human cultured tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17692290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of growth-factor-activated proliferation by anti-estrogens and effects on early gene expression of MCF-7 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17692290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 status and the efficacy of cancer therapy in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17692290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A p53-dependent mouse spindle checkpoint

1 reference

https://pubmed.ncbi.nlm.nih.gov/17692290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spindle poisons can induce polyploidy by mitotic slippage and micronucleate mononucleates in the cytokinesis-block assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/17692290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of mammalian DNA reduplication, following the release from the mitotic spindle checkpoint, requires p53 protein, but not p53-mediated transcriptional activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17692290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxicity of substituted alkyl-3,4-bis(4-methoxyphenyl)pyrrole-2-carboxylates in L1210 lymphoid leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17692290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective G1-S cell cycle checkpoint function sensitizes cells to microtubule inhibitor-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17692290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of a new tubulin-binding tetrasubstituted brominated pyrrole

1 reference

https://pubmed.ncbi.nlm.nih.gov/17692290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BCP.2007.07.003

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

ResearchGate publication ID

0 references

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