(Q40105776)

17 September 2017

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title

Thymidine as an anticancer agent, alone or in combination. A biochemical appraisal (English)

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17 September 2017

P H Ellims

1

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17 September 2017

publication date

1 December 1982

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Cancer Chemotherapy and Pharmacology

17 September 2017

published in

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17 September 2017

volume

10

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17 September 2017

issue

1

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17 September 2017

page(s)

1-6

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Effect of excess thymidine on the growth of human melanoma cells transplanted in thymus deficient nude mice

17 September 2017

cites work

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12 December 2020

Biochemical determinants of 5-fluorouracil response in vivo. The role of deoxyuridylate pool expansion

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12 December 2020

The reversal of methotrexate toxicity by thymidine with maintenance of antitumour effects

1 reference

12 December 2020

From deoxynucleotides to DNA synthesis

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12 December 2020

Selective lethal effect of thymidine on human and mouse tumor cells

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12 December 2020

Modulation of methotrexate toxicity by thymidine: sequence-dependent biochemical effects

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12 December 2020

Biochemical and antitumor effects of the combination of thymidine and 1-beta-D-arabinofuranosylcytosine against leukemia L1210

1 reference

12 December 2020

Thymidine as a chemotherapeutic agent: sensitivity of normal human marrow, peripheral blood T cells, and acute nonlymphocytic leukemia.

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12 December 2020

In vitro cytotoxic and biochemical effects of 5-aza-2'-deoxycytidine

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12 December 2020

Allosteric regulation of calf thymus ribonucleoside diphosphate reductase

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12 December 2020

Enhancement of 1-beta-D-arabinofuranosylcytosine accumulation within L1210 cells and increased cytotoxicity following thymidine exposure

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12 December 2020

The prevention of methotrexate toxicity by thymidine infusions in humans

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12 December 2020

The modulation of the thymidine triphosphate pool of Chinese hamster cells by dCMP deaminase and UDP reductase. Thymidine auxotrophy induced by CTP in dCMP deaminase-deficient lines

1 reference

12 December 2020

Potentiation of the anti-tumor activity of 5FU by thymidine and its correlation with the formation of (5FU)RNA

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12 December 2020

Comparison of pharmacokinetics of 5-fluorouracil and 5-fluorouracil with concurrent thymidine infusions in a Phase I trial

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12 December 2020

Dose- and schedule-dependent activation and drug synergism between thymidine and 5-aza-2'-deoxycytidine in a human promyelocytic leukemia cell line

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12 December 2020

High-dose thymidine infusions in patients with leukemia and lymphoma

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12 December 2020

Thymidine rescue of high-dose methotrexate in humans

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12 December 2020

Evaluation of ribonucleoside and deoxyribonucleoside triphosphate pools in cultured leukemia cells during exposure to methotrexate or methotrexate plus thymidine

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12 December 2020

Deoxyriboside Control and Synchronization of Mitosis

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12 December 2020

An overview of thymidine

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12 December 2020

Understanding the actions of carcinostatic drugs to improve chemotherapy: 5-fluorouracil

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12 December 2020

Thymidine sensitivity of cultured leukaemic lymphocytes

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12 December 2020

Deoxycytidine kinase. 3. Kinetics and allosteric regulation of the calf thymus enzyme

1 reference

12 December 2020

Lethality of human myeloblasts correlates with the incorporation of arabinofuranosylcytosine into DNA

1 reference

12 December 2020

Transport and metabolism of deoxycytidine and 1-beta-D-arabinofuranosylcytosine into cultured Novikoff rat hepatoma cells, relationship to phosphorylation, and regulation of triphosphate synthesis

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12 December 2020

"High-dose" thymidine in clinical oncology

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12 December 2020

Mechanism of deoxycytidine rescue of thymidine toxicity in human T-leukemic lymphocytes

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12 December 2020

Human thymidine kinase: purification and some properties of the TK1 isoenzyme from placenta

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12 December 2020

Antiproliferative agents and differential survival between normal and cancer cells

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12 December 2020

Correlation of thymidine-enhanced incorporation of ara-C in deoxyribonucleic acid with increased cell kill

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12 December 2020

Effects of Thymidine on Deoxyribonucleoside Triphosphate Pools and Deoxyribonucleic Acid Synthesis in Chinese Hamster Ovary Cells

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12 December 2020

Effect of thymidine on the toxicity, antitumor activity, and metabolism of 1-beta-D-arabinofuranosylcytosine in rats bearing a chemically induced colon carcinoma

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12 December 2020

Studies concerning inhibition of the synthesis of deoxycytidine by phosphorylated derivatives of thymidine

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12 December 2020

Thymidine as a chemotherapeutic agent: pharmacologic, cytokinetic, and biochemical studies in a patient with T-cell acute lymphocytic leukemia

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12 December 2020

Effect of thymidine on the sensitivity of cultured mouse tumor cells to 1-beta-D-arabinofuranosylcytosine

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12 December 2020

Thymidine and hypoxanthine requirements of normal and malignant human cells for protection against methotrexate cytotoxicity

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12 December 2020

Quantity Production of Synchronized Mammalian Cells in Suspension Culture

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12 December 2020

Deoxyribonucleoside triphosphate pools and differential thymidine sensitivities of cultured mouse lymphoma and myeloma cells

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12 December 2020

Synergistic action of 5-aza-2'-deoxycytidine and 3-deazauridine on L1210 leukemic cells and EMT6 tumor cells

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12 December 2020

Synergistic interaction between 1-beta-D-arabinofuranosylcytosine, thymidine, and hydroxyurea against human B cells and leukemic blasts in vitro

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12 December 2020

The Mechanism of Action of Inhibitors of DNA Synthesis

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12 December 2020

Biochemical basis for the enhanced toxicity of deoxyribonucleosides toward malignant human T cell lines

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12 December 2020

5-Fluorouracil incorporation into human breast carcinoma RNA correlates with cytotoxicity

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12 December 2020

Cytokinetic comparison of thymidine and leucovorin rescue of marrow in humans after exposure to high-dose methotrexate

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12 December 2020

Sensitivity of leukemic human null lymphocytes to deoxynucleosides

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12 December 2020

The regulation of thymidylate biosynthesis in Novikoff hepatoma cells and the effects of amethopterin, 5-fluorodeoxyuridine, and 3-deazauridine

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12 December 2020

Ecto-adenosine triphosphatase deficiency in cultured human T and null leukemic lymphocytes. A biochemical basis for thymidine sensitivity

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12 December 2020

Relevance of recruitment-synchronization in the scheduling of 1-beta-D-arabinofuranosylcytosine in a slow-growing acute myeloid leukemia of the rat

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12 December 2020

Phase I study of thymidine plus 5-fluorouracil infusions in advanced colorectal carcinoma

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12 December 2020

Kinetic mechanism and inhibition of human liver thymidine kinase

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12 December 2020

An update on the biochemistry of 5-fluorouracil

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12 December 2020

Role of thymidylate synthetase activity in development of methotrexate cytotoxicity

1 reference

12 December 2020

Effect of intravenous infusion of 5-aza-2'-deoxycytidine on survival time of mice with L1210 leukemia

1 reference

12 December 2020

Thymidine requirements for the rescue of patients treated with high-dose methotrexate

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12 December 2020

Inhibition of DNA polymerase-α and -β of calf thymus by 1-β-d-arabinofuranosylcytosine-5′-triphosphate

1 reference

12 December 2020

Folate metabolism in mammalian cells in culture. I Partial characterization of the folate derivatives present in L1210 mouse leukemia cells

1 reference

12 December 2020

Deoxycytidylate deaminase. Purification and some properties of the enzyme isolated from human spleen

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00257227

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Dimensions Publication ID

17 September 2017

1018149523

0 references

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