(Q40115254)

17 September 2017

title

Ski promotes tumor growth through abrogation of transforming growth factor-beta signaling in pancreatic cancer (English)

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17 September 2017

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T Ryan Heider

1

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17 September 2017

Suzanne Lyman

series ordinal

2

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17 September 2017

Robert Schoonhoven

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3

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17 September 2017

Kevin E Behrns

series ordinal

4

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17 September 2017

language of work or name

English

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publication date

1 July 2007

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17 September 2017

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17 September 2017

volume

246

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17 September 2017

issue

1

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17 September 2017

page(s)

61-68

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Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression

17 September 2017

cites work

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12 December 2020

The dissociated expression of protein and messenger RNA of DPC4 in human invasive ductal carcinoma of the pancreas and their implication for patient outcome.

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12 December 2020

Cytoplasmic localization of the oncogenic protein Ski in human cutaneous melanomas in vivo: functional implications for transforming growth factor beta signaling

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12 December 2020

The SMAD4 protein and prognosis of pancreatic ductal adenocarcinoma

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12 December 2020

Restoration of transforming growth factor-beta signaling enhances radiosensitivity by altering the Bcl-2/Bax ratio in the p53 mutant pancreatic cancer cell line MIA PaCa-2.

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12 December 2020

Frequent loss of SMAD4/DPC4 protein in colorectal cancers

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12 December 2020

Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells

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12 December 2020

Epidemiology of pancreatic cancer in Northeastern Italy: incidence, resectability rate, hospital stay, costs and survival (1990-1992)

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12 December 2020

Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN

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12 December 2020

Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads.

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12 December 2020

Requirement of a specific Sp1 site for histone deacetylase-mediated repression of transforming growth factor beta Type II receptor expression in human pancreatic cancer cells.

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12 December 2020

The Ski-binding protein C184M negatively regulates tumor growth factor-beta signaling by sequestering the Smad proteins in the cytoplasm

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12 December 2020

Unique sequence, ski, in Sloan-Kettering avian retroviruses with properties of a new cell-derived oncogene

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12 December 2020

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

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12 December 2020

Fibrogenesis and type I collagen gene regulation

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12 December 2020

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

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12 December 2020

The type II transforming growth factor-beta receptor as a tumor-suppressor gene.

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12 December 2020

Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas

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12 December 2020

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

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12 December 2020

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

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12 December 2020

Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor

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12 December 2020

High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA.

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12 December 2020

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

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12 December 2020

Transforming growth factor-beta responsiveness in DPC4/SMAD4-null cancer cells

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12 December 2020

Repression of TGF-beta signaling by the oncogenic protein SKI in human melanomas: consequences for proliferation, survival, and metastasis

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12 December 2020

Attenuation of the TGF-beta-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-beta-induced growth arrest.

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12 December 2020

The Oncoprotein Ski Acts as an Antagonist of Transforming Growth Factor-β Signaling by Suppressing Smad2 Phosphorylation

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12 December 2020

Direct interaction of Ski with either Smad3 or Smad4 is necessary and sufficient for Ski-mediated repression of transforming growth factor-beta signaling

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12 December 2020

Restoration of SMAD4 by gene therapy reverses the invasive phenotype in pancreatic adenocarcinoma cells.

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12 December 2020

SKI activates Wnt/beta-catenin signaling in human melanoma

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12 December 2020

Increased expression of c-Ski as a co-repressor in transforming growth factor-beta signaling correlates with progression of esophageal squamous cell carcinoma

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12 December 2020

Akt interacts directly with Smad3 to regulate the sensitivity to TGF-beta induced apoptosis

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12 December 2020

Amplification of SKI is a prognostic marker in early colorectal cancer

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12 December 2020

Molecular pathology of pancreatic cancer

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12 December 2020

10.1097/SLA.0B013E318070CAFA

Identifiers

DOI

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17 September 2017

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