(Q40122269)

English

Two specific inhibitors of the phosphatidylinositol 3-kinase LY294002 and wortmannin up-regulate beta1,4-galactosyltransferase I and thus sensitize SMMC-7721 human hepatocarcinoma cells to cycloheximide-induced apoptosis

scientific article published on 8 June 2007

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Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Two specific inhibitors of the phosphatidylinositol 3-kinase LY294002 and wortmannin up-regulate beta1,4-galactosyltransferase I and thus sensitize SMMC-7721 human hepatocarcinoma cells to cycloheximide-induced apoptosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

author name string

Jialin Shen

1

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Jianhai Jiang

2

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Yuanyan Wei

3

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Lei Zhou

4

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Dan Liu

5

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Jin Zhou

6

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Jianxin Gu

7

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

publication date

8 June 2007

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Molecular and Cellular Biochemistry

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

304

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

1-2

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

361-367

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

https://scigraph.springernature.com/pub.10.1007/s11010-007-9519-1

0 references

AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells

1 reference

https://api.crossref.org/works/10.1007%2FS11010-007-9519-1

21 January 2018

Transforming activity and mitosis-related expression of the AKT2 oncogene: evidence suggesting a link between cell cycle regulation and oncogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

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Cycloheximide-induced T-cell death is mediated by a Fas-associated death domain-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

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Remarkable tolerance of tumor cells to nutrient deprivation: possible new biochemical target for cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Downregulation of beta1,4-galactosyltransferase 1 inhibits CDK11(p58)-mediated apoptosis induced by cycloheximide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of phosphatidylinositide 3-kinase enhances gemcitabine-induced apoptosis in human pancreatic cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

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Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PI3K: downstream AKTion blocks apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated beta1,4-galactosyltransferase I in highly metastatic human lung cancer cells. Identification of E1AF as important transcription activator

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of two cis-regulatory regions in the murine beta 1,4-galactosyltransferase gene. Evidence for a negative regulatory element that controls initiation at the proximal site.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of beta 1,4 galactosyltransferase 1 and Gal beta1-->4GlcNAc groups in human hepatocarcinoma cell apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo antitumor activity of the phosphatidylinositol-3-kinase inhibitor, wortmannin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction by receptors with tyrosine kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

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Deleted in liver cancer (DLC) 2 encodes a RhoGAP protein with growth suppressor function and is underexpressed in hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

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Tumor necrosis factor alpha induces BID cleavage and bypasses antiapoptotic signals in prostate cancer LNCaP cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signalling through the lipid products of phosphoinositide-3-OH kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular survival: a play in three Akts

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive expression of the machinery for programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

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Destructive spondyloarthropathy of the cervical spine in long-term hemodialyzed patients: a five-year clinical radiological prospective study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylase inhibitor activates the WAF1/Cip1 gene promoter through the Sp1 sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the PI3K/Akt pathway and chemotherapeutic resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/17557191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11010-007-9519-1

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

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