(Q40125989)

17 September 2017

title

An HSV-2-based oncolytic virus deleted in the PK domain of the ICP10 gene is a potent inducer of apoptotic death in tumor cells (English)

1 reference

17 September 2017

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Fu X

1

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17 September 2017

Tao L

series ordinal

2

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17 September 2017

Zhang X

series ordinal

3

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17 September 2017

publication date

31 May 2007

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17 September 2017

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17 September 2017

volume

14

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17 September 2017

issue

16

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17 September 2017

page(s)

1218-1225

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3302971

17 September 2017

exact match

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cites work

The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) blocks apoptosis in hippocampal neurons, involving activation of the MEK/MAPK survival pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

Induction of apoptosis by herpes simplex virus type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

Oncolytic herpes simplex virus vectors for cancer virotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Experimental Therapy of Human Glioma by Means of a Genetically Engineered Virus Mutant

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

A novel multiply-mutated HSV-1 strain for the treatment of human brain tumors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant glioma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

A mutant type 2 herpes simplex virus deleted for the protein kinase domain of the ICP10 gene is a potent oncolytic virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Ras-GAP binding and phosphorylation by herpes simplex virus type 2 RR1 PK (ICP10) and activation of the Ras/MEK/MAPK mitogenic pathway are required for timely onset of virus growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Oncogenes in Ras signalling pathway dictate host-cell permissiveness to herpes simplex virus 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Targeting RAS signalling pathways in cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Effective treatment of pancreatic cancer xenografts with a conditionally replicating virus derived from type 2 herpes simplex virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Physiological significance of apoptosis in animal virus infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Apoptosis: an innate immune response to virus infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Herpes simplex virus infection and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Dual cancer-specific targeting strategy cures primary and distant breast carcinomas in nude mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Infection with oncolytic herpes simplex virus-1 induces apoptosis in neighboring human cancer cells: a potential target to increase anticancer activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Destruction of nonimmunogenic mammary tumor cells by a fusogenic oncolytic herpes simplex virus induces potent antitumor immunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Syncytia induction enhances the oncolytic potential of vesicular stomatitis virus in virotherapy for cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Inhibition of the Bcr-Abl tyrosine kinase as a therapeutic strategy for CML.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

New-age drug meets resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Overexpression of stefin A in human esophageal squamous cell carcinoma cells inhibits tumor cell growth, angiogenesis, invasion, and metastasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Expression of a fusogenic membrane glycoprotein by an oncolytic herpes simplex virus potentiates the viral antitumor effect

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302971

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302971

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Dimensions Publication ID

17 September 2017

1005410853

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1 reference