(Q40129855)

17 September 2017

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title

Structure-conformation-activity studies of glucagon and semi-synthetic glucagon analogs (English)

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17 September 2017

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16 September 2023

author name string

V. J. Hruby

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6283336

16 September 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=6283336

16 September 2023

publication date

1 April 1982

1 reference

17 September 2017

16 April 1982

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=6283336

full work available at URL

16 September 2023

http://link.springer.com/content/pdf/10.1007/BF00573846.pdf

file format

Portable Document Format

1 reference

http://link.springer.com/article/10.1007/BF00573846/fulltext.html

16 September 2023

1 reference

http://link.springer.com/content/pdf/10.1007/BF00573846

16 September 2023

1 reference

Molecular and Cellular Biochemistry

16 September 2023

published in

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17 September 2017

44

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17 September 2017

1

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17 September 2017

49-64

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https://scigraph.springernature.com/pub.10.1007/bf00573846

17 September 2017

0 references

cites work

[12-Homoarginine]glucagon: synthesis and observations on conformation, biological activity, and copper-mediated peptide cleavage

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Conformational and biological properties of a covalently linked dimer of glucagon. Reaction of mono- and bifunctional sulfenyl halides

21 January 2018

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Interaction of glucagon with dimyristoyl glycerophosphocholine.

21 January 2018

1 reference

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Combined use of proton-proton overhauser enhancements and a distance geometry algorithm for determination of polypeptide conformations. Application to micelle-bound glucagon

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00573846

Synthesis and properties of a photoaffinity probe for the glucagon receptor in hepatocyte plasma membranes

21 January 2018

1 reference

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Effects of Hofmeister salts on the self-association of glucagon

21 January 2018

1 reference

12 December 2020

1H nuclear-magnetic-resonance studies of the molecular conformation of monomeric glucagon in aqueous solution

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12 December 2020

Immunogenicity and Bioactivity of Glucagon, Modified at Methionine-27

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12 December 2020

Synthesis and characterization of a heterobifunctional photoaffinity reagent for modification of tryptophan residues and its application to the preparation of a photoreactive glucagon derivative.

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12 December 2020

Conformational and biological properties of partial sequences of glucagon

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12 December 2020

Formation and Structure of Gels and Fibrils from Glucagon

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12 December 2020

Glucagon: Structure-Function Relationships Investigated by Sequence Deletions

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12 December 2020

The effects of the trinitrophenylation of the amino groups of glucagon on its conformational properties and on its ability to activate rat liver adenylyl cyclase

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12 December 2020

Methylation of glucagon, characterization of the sulfonium derivative, and regeneration of the native covalent structure

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12 December 2020

Physical characterization of S-methylglucagon and quantitation of carbamino adduct formation

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12 December 2020

Nalpha-trinitrophenyl glucagon: an inhibitor of glucagon-stimulated cyclic AMP production and its effects on glycogenolysis

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12 December 2020

The essential role of the imidazole group of glucagon in its biological function

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12 December 2020

Polypeptide hormone interaction. I. Glucagon detergent interaction

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12 December 2020

Structure-function relations in glucagon. Properties of highly purified Des-his1-, monoiodo-, and [Des-Asn28,Thr29](homoserine lactone27)-glucagon

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12 December 2020

Conformation of glucagon. Predictions and consequences

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12 December 2020

Preparation and properties of glucagon analogs prepared by semi-synthesis from CNBr-glucagon

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12 December 2020

Physicochemical characterization of glucagon-containing lipid micelles

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12 December 2020

Glucagon structure and function. II. Increased activity of iodoglucagon

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12 December 2020

Glucagon1-6 binds to the glucagon receptor and activates hepatic adenylate cyclase

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12 December 2020

Effects of iodination of tyrosyl residues on the binding and action of glucagon at its receptor

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12 December 2020

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

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12 December 2020

The reaction of glucagon with its receptor: evidence for discrete regions of activity and binding in the glucagon molecule

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12 December 2020

Conformational nature of monomeric glucagon

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12 December 2020

Polypeptide hormone interaction. II. Glucagon binding to lysolecithin

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12 December 2020

Glucagon Conformation: Use of Opitcally Detected Magnetic Resonance and Phosphorescence of Tryptophan to Evaluate Critical Requirements for Folding of the Polypeptide Chain

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12 December 2020

Synthesis and isolation of a glucagon antagonist

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12 December 2020

A reassessment of structure-function relationships in glucagon. Glucagon1-21 is a full agonist

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12 December 2020

Relation between conformation and association state. A study of the association equilibrium of glucagon

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12 December 2020

Reversible unfolding of glucagon by urea and temperature changes

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12 December 2020

Labeling of glucagon binding components in hepatocyte plasma membranes

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12 December 2020

A LOW-RESOLUTION STRUCTURAL MODEL FOR CUBIC GLUCAGON BASED ON PACKING OF CYLINDERS

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12 December 2020

Semisynthetic glucagon derivatives for structure-function studies

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12 December 2020

1-Penicillamine,2-leucineoxytocin. Synthesis and pharmacological and conformational studies of a potent peptide hormone inhibitor

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12 December 2020

Synthesis, pharmacological, conformational, and dynamic studies of the potent hormone antagonists [1-penicillamine, 4-threonine]-oxytocin and [1-penicillamine, 2-phenylalanine, 4-threonine]-oxytocin. Conformational and dynamic considerations in the

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12 December 2020

Selectively blocked and des-histidine-glucagons: preparation and effects on hepatic adenylate cyclase activity

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12 December 2020

Glucagon structure-function relationships using isolated rat hepatocytes

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12 December 2020

Evidence of association of glucagon from optical rotatory dispersion and concentration-difference spectra

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12 December 2020

The essential role of glucagon in the pathogenesis of diabetes mellitus

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12 December 2020

Conformational study of the potent peptide hormone antagonist [1-penicillamine,2-leucine]oxytocin in aqueous solution

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12 December 2020

[On the synthesis of glucagon. Preparation of the entire sequence]

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12 December 2020

Structural requirements for glucagon receptor binding and activation of adenylate cyclase in liver. Study of chemically modified forms of the hormone, including N alpha-trinitrophenyl glucagon, an antagonist

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12 December 2020

Conformational states of glucagon

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12 December 2020

The circular dichroism of glucagon solutions

1 reference

12 December 2020

Effects of chemical and enzymatic modifications of glucagon on its activation of hepatic adenyl cyclase.

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12 December 2020

Glucagon amino groups. Evaluation of modifications leading to antagonism and agonism

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12 December 2020

Iodoglucagon. Preparation and Characterization

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12 December 2020

On the Biological and Chemical Reactivity of Carbamylated Glucagon

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12 December 2020

Properties of amidinated glucagons

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12 December 2020

Carboxyl group modification in glucagon

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12 December 2020

Size and shape of the model lipoprotein complex formed between glucagon and dimyristoylglycerophosphocholine

1 reference

12 December 2020

Self-association of glucagon, Equilibrium studies

1 reference

12 December 2020

The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. 3. Binding of glucagon: method of assay and specificity

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12 December 2020

(Des-histidine 1) (N epsilon-phenylthiocarbamoyllysine 12)-glucagon: effects on glycogenolysis in perfused rat liver

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12 December 2020

Glucagon structure and function. Preparation and characterization of nitroglucagon and aminoglucagon.

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12 December 2020

Role of glucagon in the pathogenesis of diabetes: The status of the controversy

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12 December 2020

The effects of synthetic glucagon fragments on glucose-6-phosphate dehydrogenase. II

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12 December 2020

Binding of 125I-labeled glucagon and glucagon-stimulated accumulation of adenosine 3‘:5‘-monophosphate in isolated intact rat hepatocytes. Evidence for receptor heterogeneity

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12 December 2020

Conformational Properties of Cyanogen Bromide-cleaved Glucagon

1 reference

12 December 2020

Synthesis of the nonacosapeptide corresponding to mammalian glucagon

1 reference

12 December 2020

Presence ot trimers in glucagon solution

1 reference

12 December 2020

Biochemical Properties of Hormone-Sensitive Adenylate Cyclase

1 reference

12 December 2020

X-ray analysis of glucagon and its relationship to receptor binding

1 reference

12 December 2020

Acetylglucagon: Preparation and Characterization

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12 December 2020

Thermodynamics of the self-association of glucagon

1 reference

12 December 2020

Molecular interactions in the model lipoprotein complex formed between glucagon and dimyristoylglycerophosphocholine

1 reference

12 December 2020

Proton NMR studies of the association and folding of glucagon in solution

1 reference

12 December 2020

Self-association of glucagon as measured by the optical properties of rhodamine 6G

1 reference

12 December 2020

Multiple environments of tryptophan in glucagon

1 reference

12 December 2020

Preparation of 2-thioltryptophan-glucagon and (tryptophan-S-glucagon)2. Differences in binding to the glucagon receptor in the hepatic adenylate cyclase system

1 reference

12 December 2020

Total synthesis of crystalline glucagon by the method of solid phase condensation of fragments. Protein Synthesis Group, Shanghai Institute of Biochemistry, Academia Sinica

1 reference

12 December 2020

Relative conformational rigidity in oxytocin and (1-penicillamine)-oxytocin: a proposal for the relationship of conformational flexibility to peptide hormone agonism and antagonism

1 reference

12 December 2020

A conformational study of glucagon

1 reference

12 December 2020

A Study of the Conformational Properties of Glucagon in the Presence of Glycols

1 reference

12 December 2020

Conformational changes of protected glucogon fragments bound to lysolecithin

1 reference

12 December 2020

Thermodynamics of glucagon aggregation

1 reference

12 December 2020

Structural studies on polypeptide hormones. I. Fluorescence.

1 reference

12 December 2020

Solid-phase synthesis of crystalline glucagon

1 reference

12 December 2020

Studies with glucagon analogs

1 reference

12 December 2020

Acta Crystallographica

71

A25

S185

W. P. Haugen

1969

1 reference

16 September 2023

Identifiers

DOI

10.1007/BF00573846

1 reference

17 September 2017

1 reference