(Q40135881)

English

Glycogen synthase kinase-3beta and p38 phosphorylate cyclin D2 on Thr280 to trigger its ubiquitin/proteasome-dependent degradation in hematopoietic cells

scientific article published on 7 May 2007

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scholarly article

1 reference

Europe PubMed Central

17 September 2017

Glycogen synthase kinase-3beta and p38 phosphorylate cyclin D2 on Thr280 to trigger its ubiquitin/proteasome-dependent degradation in hematopoietic cells (English)

1 reference

Europe PubMed Central

17 September 2017

ubiquitin-proteasome system

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phosphorylation

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author name string

A Kida

1

1 reference

Europe PubMed Central

17 September 2017

K Kakihana

2

1 reference

Europe PubMed Central

17 September 2017

S Kotani

3

1 reference

Europe PubMed Central

17 September 2017

T Kurosu

4

1 reference

Europe PubMed Central

17 September 2017

O Miura

5

1 reference

Europe PubMed Central

17 September 2017

language of work or name

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publication date

7 May 2007

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Europe PubMed Central

17 September 2017

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Europe PubMed Central

17 September 2017

26

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Europe PubMed Central

17 September 2017

46

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Europe PubMed Central

17 September 2017

6630-6640

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Europe PubMed Central

17 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210490

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Regulation of G1/S transition by cyclins D2 and D3 in hematopoietic cells

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Identification of mutations that disrupt phosphorylation-dependent nuclear export of cyclin D1.

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Genetic replacement of cyclin D1 function in mouse development by cyclin D2.

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P38SAPK2 phosphorylates cyclin D3 at Thr-283 and targets it for proteasomal degradation

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Osmotic stress regulates the stability of cyclin D1 in a p38SAPK2-dependent manner

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Cyclin D2 dysregulation by chromosomal translocations to TCR loci in T-cell acute lymphoblastic leukemias

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Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

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Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

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Cytokine receptor signalling

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The glamour and gloom of glycogen synthase kinase-3

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Deregulation of cyclin D2 by juxtaposition with T-cell receptor alpha/delta locus in t(12;14)(p13;q11)-positive childhood T-cell acute lymphoblastic leukemia.

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Cell cycle progression without cyclin D-CDK4 and cyclin D-CDK6 complexes

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p38 MAP kinase plays a role in G2 checkpoint activation and inhibits apoptosis of human B cell lymphoma cells treated with etoposide

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IkappaB kinase alpha regulates subcellular distribution and turnover of cyclin D1 by phosphorylation

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Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex

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Identifiers

10.1038/SJ.ONC.1210490

1 reference

Europe PubMed Central

17 September 2017

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1 reference

Europe PubMed Central

17 September 2017

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