(Q40138538)

17 September 2017

title

Ezetimibe interferes with cholesterol trafficking from the plasma membrane to the endoplasmic reticulum in CaCo-2 cells (English)

1 reference

17 September 2017

main subject

endoplasmic reticulum

0 references

1 reference

F Jeffrey Field

1

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17 September 2017

Kim Watt

series ordinal

2

1 reference

17 September 2017

Satya N Mathur

series ordinal

3

1 reference

17 September 2017

publication date

1 May 2007

1 reference

Journal of Lipid Research

17 September 2017

published in

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17 September 2017

volume

48

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17 September 2017

issue

8

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17 September 2017

page(s)

1735-1745

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Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption

17 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M700029-JLR200

Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M700029-JLR200

Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M700029-JLR200

Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M700029-JLR200

The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M700029-JLR200

Ezetimibe potently inhibits cholesterol absorption but does not affect acute hepatic or intestinal cholesterol synthesis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M700029-JLR200

The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)

21 January 2018

1 reference

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Evidence for a Niemann-pick C (NPC) gene family: identification and characterization of NPC1L1.

21 January 2018

1 reference

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Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

21 January 2018

1 reference

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Niemann-Pick type C: a disorder of cellular cholesterol trafficking

21 January 2018

1 reference

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Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene

21 January 2018

1 reference

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21 January 2018

1 reference

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Recombinant acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) purified to essential homogeneity utilizes cholesterol in mixed micelles or in vesicles in a highly cooperative manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M700029-JLR200

Differential mobilization of newly synthesized cholesterol and biosynthetic sterol precursors from cells

21 January 2018

1 reference

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Real-time PCR for mRNA quantitation

21 January 2018

1 reference

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2-Azetidinones as inhibitors of cholesterol absorption.

21 January 2018

1 reference

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Hypocholesterolemic activity of a novel inhibitor of cholesterol absorption, SCH 48461

21 January 2018

1 reference

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The identification of intestinal scavenger receptor class B, type I (SR-BI) by expression cloning and its role in cholesterol absorption.

21 January 2018

1 reference

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Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663

21 January 2018

1 reference

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The discovery of ezetimibe: a view from outside the receptor

21 January 2018

1 reference

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In vivo responsiveness to ezetimibe correlates with niemann-pick C1 like-1 (NPC1L1) binding affinity: Comparison of multiple species NPC1L1 orthologs.

21 January 2018

1 reference

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Stanol esters decrease plasma cholesterol independently of intestinal ABC sterol transporters and Niemann-Pick C1-like 1 protein gene expression

21 January 2018

1 reference

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Cholesterol-regulated translocation of NPC1L1 to the cell surface facilitates free cholesterol uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M700029-JLR200

Multiple, independently regulated pathways of cholesterol transport across the intestinal epithelial cells

21 January 2018

1 reference

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Effect of ezetimibe on the in vivo kinetics of apoB-48 and apoB-100 in men with primary hypercholesterolemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M700029-JLR200

Modulation of human Niemann-Pick C1-like 1 gene expression by sterol: Role of sterol regulatory element binding protein 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M700029-JLR200

ACAT2 deficiency limits cholesterol absorption in the cholesterol-fed mouse: impact on hepatic cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M700029-JLR200

The molecular mechanisms underlying the reduction of LDL apoB-100 by ezetimibe plus simvastatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M700029-JLR200

Localization and role of NPC1L1 in cholesterol absorption in human intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M700029-JLR200

10.1194/JLR.M700029-JLR200

21 January 2018

Identifiers

DOI

1 reference

17 September 2017

1 reference