(Q40148424)

17 September 2017

Glucokinase activator PSN-GK1 displays enhanced antihyperglycaemic and insulinotropic actions (English)

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17 September 2017

M C T Fyfe

1

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17 September 2017

J R White

2

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17 September 2017

A Taylor

3

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17 September 2017

R Chatfield

4

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17 September 2017

E Wargent

5

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17 September 2017

R L Printz

6

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17 September 2017

T Sulpice

7

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17 September 2017

J G McCormack

8

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17 September 2017

M J Procter

9

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17 September 2017

C Reynet

10

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17 September 2017

P S Widdowson

11

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17 September 2017

P Wong-Kai-In

12

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17 September 2017

6 April 2007

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17 September 2017

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17 September 2017

50

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17 September 2017

6

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17 September 2017

1277-1287

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https://scigraph.springernature.com/pub.10.1007/s00125-007-0646-8

17 September 2017

0 references

cites work

The place of sulfonylureas in the therapy for type 2 diabetes mellitus

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-007-0646-8

The network of glucokinase-expressing cells in glucose homeostasis and the potential of glucokinase activators for diabetes therapy

21 January 2018

1 reference

12 December 2020

Small molecule glucokinase activators as glucose lowering agents: a new paradigm for diabetes therapy

1 reference

12 December 2020

Current therapies and emerging targets for the treatment of diabetes

1 reference

12 December 2020

Human duodenal enteroendocrine cells: source of both incretin peptides, GLP-1 and GIP.

1 reference

12 December 2020

The physiological role of glucokinase binding and translocation in hepatocytes

1 reference

12 December 2020

Biochemical basis of glucokinase activation and the regulation by glucokinase regulatory protein in naturally occurring mutations

1 reference

12 December 2020

Do sulfonylurea drugs increase the risk of cardiac events?

1 reference

12 December 2020

Mechanisms of beta-cell death in type 2 diabetes.

1 reference

12 December 2020

Stimulation of hepatocyte glucose metabolism by novel small molecule glucokinase activators

1 reference

12 December 2020

A comparison of agents used to manage type 2 diabetes mellitus: need for reappraisal of traditional approaches

1 reference

12 December 2020

Allosteric activators of glucokinase: potential role in diabetes therapy

1 reference

12 December 2020

Glucokinase is a critical regulator of ventromedial hypothalamic neuronal glucosensing

1 reference

12 December 2020

Type 2 diabetes market.

1 reference

12 December 2020

An allosteric activator of glucokinase impairs the interaction of glucokinase and glucokinase regulatory protein and regulates glucose metabolism

1 reference

12 December 2020

Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase

1 reference

12 December 2020

Tweaking the glucose sensor: adjusting glucokinase activity with activator compounds

1 reference

12 December 2020

Predictive blood glucose lowering efficacy by Glucokinase activators in high fat fed female Zucker rats

1 reference

12 December 2020

Long-term overexpression of glucokinase in the liver of transgenic mice leads to insulin resistance.

1 reference

12 December 2020

Two birds with one stone: novel glucokinase activator stimulates glucose-induced pancreatic insulin secretion and augments hepatic glucose metabolism

1 reference

12 December 2020

Glycogen-targeting subunits and glucokinase differentially affect pathways of glycogen metabolism and their regulation in hepatocytes

1 reference

12 December 2020

Glucose regulation of glucose transporters in cultured adult and fetal hepatocytes.

1 reference

12 December 2020

Glucokinase and glucose homeostasis: proven concepts and new ideas

1 reference

12 December 2020

A glucose sensor role for glucokinase in anterior pituitary cells.

1 reference

12 December 2020

Rationale and options for combination therapy in the treatment of Type 2 diabetes

1 reference

12 December 2020

Targeting glucokinase activation for the treatment of type 2 diabetes--a status review.

1 reference

12 December 2020

Metabolic impact of glucokinase overexpression in liver: lowering of blood glucose in fed rats is accompanied by hyperlipidemia.

1 reference

12 December 2020

Design of a potent, soluble glucokinase activator with excellent in vivo efficacy.

1 reference

12 December 2020

Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities.

1 reference

12 December 2020

[Val12] HRAS downregulates GLUT2 in beta cells of transgenic mice without affecting glucose homeostasis

1 reference

12 December 2020

Intracerebroventricular infusion of glucose, insulin, and the adenosine monophosphate-activated kinase activator, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside, controls muscle glycogen synthesis

1 reference

12 December 2020

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

1 reference

12 December 2020

From Clinicogenetic Studies of Maturity-Onset Diabetes of the Young to Unraveling Complex Mechanisms of Glucokinase Regulation

1 reference

12 December 2020

Quantitation of hepatic glucose fluxes and pathways of hepatic glycogen synthesis in conscious mice

1 reference

12 December 2020

A novel glucokinase activator modulates pancreatic islet and hepatocyte function

1 reference

12 December 2020

Small molecule glucokinase activators as novel anti-diabetic agents.

1 reference

12 December 2020

Identification of fructose 6-phosphate- and fructose 1-phosphate-binding residues in the regulatory protein of glucokinase

1 reference

12 December 2020

The role of GLUT2 in dietary sugar handling.

1 reference

12 December 2020

Dose-response relation between sulfonylurea drugs and mortality in type 2 diabetes mellitus: a population-based cohort study

1 reference

12 December 2020

10.1007/S00125-007-0646-8

Identifiers

DOI

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17 September 2017

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