(Q40149455)

17 September 2017

1 reference

title

Paracetamol overdosage. Pharmacological considerations and clinical management (English)

1 reference

17 September 2017

Paracetamol Overdosage Pharmacological Considerations and Clinical Management (English)

1 reference

10.2165/00003495-198325030-00002

Crossref

DOI

https://api.crossref.org/works/10.2165/00003495-198325030-00002

3 October 2023

1 reference

L. F. Prescott

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6343056

3 October 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=6343056

3 October 2023

publication date

1 March 1983

1 reference

17 September 2017

1 reference

17 September 2017

25

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17 September 2017

3

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17 September 2017

290-314

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https://scigraph.springernature.com/pub.10.2165/00003495-198325030-00002

17 September 2017

0 references

cites work

Serum ferritin levels in acute hepatocellular damage from paracetamol overdosage

1 reference

12 December 2020

Effect of acetaminophen (paracetamol) and its antagonists on glutathione (GSH) content in rat liver

1 reference

12 December 2020

Cysteamine, methionine, and penicillamine in the treatment of paracetamol poisoning

1 reference

12 December 2020

Histopathological changes in the liver following a paracetamol overdose: Correlation with clinical and biochemical parameters

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12 December 2020

Antidotal effects of dimethyl sulphoxide against paracetamol-, bromobenzene-, and thioacetamide-induced hepatotoxicity

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12 December 2020

Increased paracetamol-induced hepatotoxicity after chronic alcohol consumption

1 reference

12 December 2020

Late treatment of paracetamol poisoning with mercaptamine

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12 December 2020

Massive hepatic necrosis and focal necrotising myopathy

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12 December 2020

Use of isolated kidney cells for study of drug metabolism

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12 December 2020

Biochemical Changes after Hepatic Injury from Toxic Doses of Acetaminophen or Furosemide

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12 December 2020

Treatment of acute paracetamol poisoning

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12 December 2020

Paracetamol overdose in man: relationship between pattern of urinary metabolites and severity of liver damage

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12 December 2020

The spectrum of paracetamol (acetaminophen) overdose: clinical and epidemiological studies

1 reference

12 December 2020

Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo

1 reference

12 December 2020

Acetaminophen overdoses at a county hospital: a year's experience

1 reference

12 December 2020

Treatment of acute paracetamol poisoning

1 reference

12 December 2020

Liver cytosol catalyzed conjugation of reduced glutathione with a reactive metabolite of acetaminophen

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12 December 2020

Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism

1 reference

12 December 2020

Evidence for the involvement of N-acetyl-p- quinoneimine in acetaminophen metabolism

1 reference

12 December 2020

Analgesic poisoning: a multi-centre, prospective survey

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12 December 2020

Acute liver necrosis following overdose of paracetamol

1 reference

12 December 2020

Controlled trial of cysteamine in treatment of acute paracetamol (acetaminophen) poisoning

1 reference

12 December 2020

Impairment in the hepatic clearance of (35S)-bromosulphophthalein in paracetamol-intoxicated rats

1 reference

12 December 2020

The estimation of acetanilide and its metabolic products, aniline, N-acetyl p-aminophenol and p-amino-phenol, free and total conjugated, in biological fluids and tissues.

1 reference

12 December 2020

Age as a variable in acetaminophen overdose

1 reference

12 December 2020

Serum enzyme activities and hepatic triglyceride levels in acute and subacute acetaminophen-treated rats

1 reference

12 December 2020

Methionine and Cysteamine in Paracetamol (Acetaminophen) Overdose, Prospective Controlled Trial of Early Therapy

1 reference

12 December 2020

Protective role of S-adenosyl-l-methionine against acetaminophen induced mortality and hepatotoxicity in mice

1 reference

12 December 2020

Species differences in hepatic glutathione depletion, covalent binding and hepatic necrosis after acetaminophen.

1 reference

12 December 2020

Treatment of paracetamol (acetaminophen) poisoning with N-acetylcysteine

1 reference

12 December 2020

Host susceptibility and acetaminophen liver injury

1 reference

12 December 2020

Reversal of experimental paracetamol toxicosis with N-acetylcysteine

1 reference

12 December 2020

Severe barbiturate and paracetamol overdose: the simultaneous removal of both poisons by haemoperfusion

1 reference

12 December 2020

Paracetamol metabolism following overdosage: application of high performance liquid chromatography

1 reference

12 December 2020

Haemodialysis in paracetamol self-poisoning.

1 reference

12 December 2020

The third Lilly Prize Lecture. University of London, January, 1979. The nephrotoxicity and hepatotoxicity of antipyretic analgesics

1 reference

12 December 2020

Liver damage after paracetamol overdose. Comparison of liver-function tests, fasting serum bile acids, and liver histology

1 reference

12 December 2020

Prevention of paracetamol-induced liver damage in mice with glutathione

1 reference

12 December 2020

Paracetamol-induced acute pancreatitis.

1 reference

12 December 2020

A dog model of fulminant hepatic failure produced by paracetamol administration

1 reference

12 December 2020

A controlled trial of heparin therapy in the coagulation defect of paracetamol-induced hepatic necrosis

1 reference

12 December 2020

Factors contributing to mortality in paracetamol-induced hepatic failure

1 reference

12 December 2020

Paracetamol metabolism and toxicity in isolated hepatocytes from rat and mouse

1 reference

12 December 2020

Inappropriate Methods for the Emergency Determination of Plasma Paracetamol

1 reference

12 December 2020

Glutathione: a protective mechanism against hepatotoxicity

1 reference

12 December 2020

Letter: B.A.L. in paracetamol poisoning

1 reference

12 December 2020

The effect of age on paracetamol hepatotoxicity in mice

1 reference

12 December 2020

Oral methionine in the treatment of severe paracetamol (Acetaminophen) overdose

1 reference

12 December 2020

Effects of microsomal enzyme induction on paracetamol metabolism in man

1 reference

12 December 2020

Experimental acetaminophen-induced hepatic necrosis: biochemical and electron microscopic study of cysteamine protection

1 reference

12 December 2020

Acute renal failure associated with acetaminophen ingestion: report of a case and review of the literature

1 reference

12 December 2020

Disturbances in Glucose Metabolism in Patients with Liver Damage Due to Paracetamol Overdose

1 reference

12 December 2020

Paracetamol-induced acute pancreatitis

1 reference

12 December 2020

Acetaminophen toxicity

1 reference

12 December 2020

Potentiation of acetaminophen hepatotoxicity by alcohol

1 reference

12 December 2020

Treatment of acetaminophen poisoning. The use of oral methionine

1 reference

12 December 2020

Extracorporeal treatment of salicylate or acetaminophen poisoning--is there a role?

1 reference

12 December 2020

Acetaminophen-induced hepatic injury: protective role of glutathione in man and rationale for therapy.

1 reference

12 December 2020

Serum transaminase levels after experimental paracetamol-induced hepatic necrosis

1 reference

12 December 2020

Pharmacokinetics of acetaminophen in the human neonate: formation of acetaminophen glucuronide and sulfate in relation to plasma bilirubin concentration and D-glucaric acid excretion

1 reference

12 December 2020

Acetaminophen poisoning

1 reference

12 December 2020

Interactions between ethanol and other hepatotoxic agents

1 reference

12 December 2020

Effect of N-acetylcysteine on the pharmacokinetics of acetaminophen in rats

1 reference

12 December 2020

Paracetamol-induced acute renal failure in the absence of fulminant liver damage

1 reference

12 December 2020

Experimental paracetamol-induced hepatic necrosis: A light-and electron-microscope, and histochemical study

1 reference

12 December 2020

Protection of rats against the hepatotoxic effect of paracetamol

1 reference

12 December 2020

Molecular basis for several drug-induced nephropathies

1 reference

12 December 2020

The fate of acetophenetidin in man and methods for the estimation of acetophenetidin and its metabolites in biological material

1 reference

12 December 2020

Acute paracetamol poisoning

1 reference

12 December 2020

Reduction of acetaminophen toxicity by sodium sulfate in mice

1 reference

12 December 2020

Acetaminophen toxicosis in the cat

1 reference

12 December 2020

Early prediction of the outcome of a paracetamol overdose based on an analysis of 163 patients

1 reference

12 December 2020

Controlled trial of cysteamine and dimercaprol after paracetamol overdose

1 reference

12 December 2020

The epidemiology of acute acetaminophen poisoning in England and Wales

1 reference

12 December 2020

The influence of ethanol pretreatment on the effects of nine hepatotoxic agents

1 reference

12 December 2020

Hepatic damage and death from overdose of paracetamol

1 reference

12 December 2020

Hepatotoxicity of paracetamol enhanced by ingestion of alcohol: report of two cases

1 reference

12 December 2020

Evaluation of paracetamol-induced damage in liver biopsies. Acute changes and follow-up findings

1 reference

12 December 2020

Paracetamol metabolism in the isolated perfused rat liver with further metabolism of a biliary paracetamol conjugate by the small intestine

1 reference

12 December 2020

Ethanol induction of acetaminophen toxicity and metabolism

1 reference

12 December 2020

Fatal acetaminophen overdosage in a young child

1 reference

12 December 2020

Plasma-paracetamol half-life and hepatic necrosis in patients with paracetamol overdosage

1 reference

12 December 2020

Varying effects of sulfhydryl nucleophiles on acetaminophen oxidation and sulfhydryl adduct formation

1 reference

12 December 2020

Successful treatment of severe paracetamol overdosage with cysteamine

1 reference

12 December 2020

Liver damage after paracetamol

1 reference

12 December 2020

Intravenous N-acetylcystine: the treatment of choice for paracetamol poisoning

1 reference

12 December 2020

The chief scientist reports ... prevention of hepatic necrosis following paracetamol overdosage

1 reference

12 December 2020

Effect of Sodium Sulfate on Acetaminophen Elimination by Rats

1 reference

12 December 2020

Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen.

1 reference

12 December 2020

Paracetamol-induced hepatic necrosis in the mouse-relationship between covalent binding, hepatic glutathione depletion and the protective effect of alpha-mercaptopropionylglycine

1 reference

12 December 2020

Renal necrosis, glutathione depletion, and covalent binding after acetaminophen

1 reference

12 December 2020

Paracetamol-induced acute renal failure in the absence of fulminant liver damage.

1 reference

12 December 2020

Death in an Adolescent Following an Overdose of Acetaminophen and Phenobarbital

1 reference

12 December 2020

CHRONIC TOXICITY STUDIES ON PHENACETIN, N-ACETYL-P-AMINOPHENOL (NAPA) AND ACETYLSALICYLIC ACID ON CATS

1 reference

12 December 2020

Treatment of severe acetaminophen poisoning with intravenous acetylcysteine

1 reference

12 December 2020

Liver necrosis and myocardiopathy following paracetamol overdosage

1 reference

12 December 2020

The effect of diet on the toxicity of paracetamol and the safety of paracetamol-methionine mixtures

1 reference

12 December 2020

Kinetics and metabolism of paracetamol and phenacetin

1 reference

12 December 2020

Acute myocardial necrosis in paracetamol poisoning

1 reference

12 December 2020

Liver necrosis from paracetamol

1 reference

12 December 2020

Vitamin E protection of the liver from paracetamol in the rat

1 reference

12 December 2020

Concomitant alcohol and drug abuse enhancing acetaminophen toxicity. Report of a case

1 reference

12 December 2020

Acetaminophen: report of an unusual poisoning

1 reference

12 December 2020

Acetaminophen elimination kinetics in neonates, children, and adults

1 reference

12 December 2020

Early Inhibition of Hepatic Bilirubin Conjugation after Paracetamol (Acetaminophen) Administration in the Rat

1 reference

12 December 2020

Potentiation by Previous Drug Therapy of Hepatotoxicity following Paracetamol Overdosage

1 reference

12 December 2020

Pathophysiology of acetaminophen overdosage toxicity: implications for management

1 reference

12 December 2020

Self-poisoning and suicide due to paracetamol

1 reference

12 December 2020

Effect of Liposomal Entrapment on the Protective Action of Glutathione against Paracetamol-Induced Liver Necrosis

1 reference

12 December 2020

In situ formation of the acetaminophen metabolite covalently bound in kidney and lung. Supportive evidence provided by total hepatectomy

1 reference

12 December 2020

1 reference

12 December 2020

An Animal Model of Fulminant Hepatic Failure: A Feasibility Study

1 reference

12 December 2020

The effects of hepatic and renal damage on paracetamol metabolism and excretion following overdosage.: A pharmacokinetic study

1 reference

12 December 2020

Acetaminophen overdose. 662 cases with evaluation of oral acetylcysteine treatment

1 reference

12 December 2020

Effect of chronic ethanol administration on drug metabolism in isolated hepatocytes with emphasis on paracetamol activation

1 reference

12 December 2020

Liver damage and impaired glucose tolerance after paracetamol overdosage.

1 reference

12 December 2020

Disordered Hemostasis in Liver Damage from Paracetamol Overdose

1 reference

12 December 2020

Paracetamol poisoning

1 reference

12 December 2020

Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro

1 reference

12 December 2020

Distalgesic and paracetamol poisoning

1 reference

12 December 2020

Early changes in coagulation following a paracetamol overdose and a controlled trial of fresh frozen plasma therapy

1 reference

12 December 2020

Evidence that acetaminophen and N-hydroxyacetaminophen form a common arylating intermediate, N-acetyl-p-benzoquinoneimine.

1 reference

12 December 2020

Acetaminophen overdose: incidence, diagnosis, and management in 416 patients

1 reference

12 December 2020

Repeated self-poisoning with paracetamol

1 reference

12 December 2020

Charcoal haemoperfusion for paracetamol overdose

1 reference

12 December 2020

Reduction of absorption of paracetamol by activated charcoal and cholestyramine: a possible therapeutic measure

1 reference

12 December 2020

Haemoperfusion in 'late' paracetamol poisoning

1 reference

12 December 2020

Anaphylactoid reaction to N-acetylcysteine

1 reference

12 December 2020

Liver toxicity after acetaminophen ingestion. Inadequacy of the dose estimate as an index of risk

1 reference

12 December 2020

Hepatic Glutathione Depletion and Impaired Bromosulphthalein Clearance Early after Paracetamol Overdose in Man and the Rat

1 reference

12 December 2020

Treatment of acetaminophen overdosage with N-acetylcysteine

1 reference

12 December 2020

Predicting outcome of paracetamol poisoning by use 14C-aminopyrine breath test

1 reference

12 December 2020

Aspirin or paracetamol?

1 reference

12 December 2020

Effect of activated charcoal on acetaminophen absorption

1 reference

12 December 2020

Treating acute acetaminophen poisoning with acetylcysteine

1 reference

12 December 2020

Frequency of renal impairment in paracetamol overdose compared with other causes of acute liver damage

1 reference

12 December 2020

Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione

1 reference

12 December 2020

Cysteamine-induced Increase of Cellular Glutathione-level : A New Hypothesis of the Radioprotective Mechanism

1 reference

12 December 2020

Abnormal drug metabolism after barbiturate and paracetamol overdose

1 reference

12 December 2020

The effect of dichloralphenazone pretreatment on paracetamol hepatotoxicity in mice

1 reference

12 December 2020

Intravenous N-acetylcysteine: the treatment of choice in paracetamol poisoning?

1 reference

12 December 2020

Paracetamol poisoning in children

1 reference

12 December 2020

Fatal massive hepatic necrosis following acetaminophen overdose

1 reference

12 December 2020

Experimental paracetamol-induced hepatic necrosis: A histopathological study

1 reference

12 December 2020

The treatment of paracetamol overdose with charcoal haemoperfusion and cysteamine

1 reference

12 December 2020

Acetaminophen kinetics in acutely poisoned patients

1 reference

12 December 2020

The curative effects of cysteamine, cysteine, and dithiocarb in experimental paracetamol poisoning

1 reference

12 December 2020

10.2165/00003495-198325030-00002

Identifiers

DOI

1 reference

Dimensions Publication ID

17 September 2017

0 references

1 reference