(Q40158789)

English

Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-kappaB and Notch1 signaling

scientific article published on 15 March 2007

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scholarly article

1 reference

Europe PubMed Central

18 September 2017

Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-kappaB and Notch1 signaling (English)

1 reference

Europe PubMed Central

18 September 2017

1 reference

based on heuristic

inferred from title

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based on heuristic

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author name string

Xiaohua Gao

1

1 reference

Europe PubMed Central

18 September 2017

Dorrah Deeb

2

1 reference

Europe PubMed Central

18 September 2017

Hao Jiang

3

1 reference

Europe PubMed Central

18 September 2017

Yongbo Liu

4

1 reference

Europe PubMed Central

18 September 2017

Scott A Dulchavsky

5

1 reference

Europe PubMed Central

18 September 2017

Subhash C Gautam

6

1 reference

Europe PubMed Central

18 September 2017

publication date

15 March 2007

1 reference

Europe PubMed Central

18 September 2017

Journal of Neuro-Oncology

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Europe PubMed Central

18 September 2017

84

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Europe PubMed Central

18 September 2017

2

1 reference

Europe PubMed Central

18 September 2017

147-157

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Europe PubMed Central

18 September 2017

https://scigraph.springernature.com/pub.10.1007/s11060-007-9364-9

0 references

NF-kappaB in cancer: from innocent bystander to major culprit

1 reference

https://api.crossref.org/works/10.1007%2FS11060-007-9364-9

21 January 2018

Function and activation of NF-kappa B in the immune system

1 reference

https://api.crossref.org/works/10.1007%2FS11060-007-9364-9

21 January 2018

The novel triterpenoid CDDO-Me suppresses MAPK pathways and promotes p38 activation in acute myeloid leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The novel triterpenoid CDDO and its derivatives induce apoptosis by disruption of intracellular redox balance

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel triterpenoids suppress inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) in mouse macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis. Its significance in cancer and cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel synthetic oleanane triterpenoids: a series of highly active inhibitors of nitric oxide production in mouse macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Malignant glioma: who benefits from adjuvant chemotherapy?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-allergic and anti-inflammatory triterpenes from the herb of Prunella vulgaris

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of programmed (apoptotic) cell death during the progression and therapy for prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct stimulation of apoptotic signaling by soluble Apo2l/tumor necrosis factor-related apoptosis-inducing ligand leads to selective killing of glioma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overcoming Antiapoptotic Responses to Promote Chemosensitivity in Metastatic Colorectal Cancer to the Liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic triterpenoids cooperate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the tumor-promoting action of 12-O-tetradecanoylphorbol-13-acetate by some oleanane-type triterpenoid compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of chemotherapeutic agents following antagonism of nuclear factor kappa B in human gliomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of FasL and TRAIL induced apoptosis pathways in glioma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of resistance to therapy and tumor cell survival.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Malignant glioma: should chemotherapy be overthrown by experimental treatments?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlates of survival and the Daumas-Duport grading system for astrocytomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perturbations of the AKT signaling pathway in human cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transcription factor NF-kappaB: control of oncogenesis and cancer therapy resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Notch1 and notch2 have opposite effects on embryonal brain tumor growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomized trial of three chemotherapy regimens and two radiotherapy regimens and two radiotherapy regimens in postoperative treatment of malignant glioma. Brain Tumor Cooperative Group Trial 8001.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoprevention of cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Meta-analysis of radiation therapy with and without adjuvant chemotherapy for malignant gliomas in adults.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design and synthesis of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, a novel and highly active inhibitor of nitric oxide production in mouse macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid and related compounds inhibit growth of colon cancer cells through peroxisome proliferator-activated receptor gamma-dependent and -independent pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

APO2 ligand: a novel lethal weapon against malignant glioma?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic triterpenoids enhance transforming growth factor beta/Smad signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Death receptors: signaling and modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17361329

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11060-007-9364-9

1 reference

Europe PubMed Central

18 September 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

18 September 2017

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