(Q40163109)

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Molecular interactions of the gating modifier toxin ProTx-II with NaV 1.5: implied existence of a novel toxin binding site coupled to activation

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Europe PubMed Central

PubMed publication ID

18 September 2017

Molecular interactions of the gating modifier toxin ProTx-II with NaV 1.5: implied existence of a novel toxin binding site coupled to activation (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

molecular interaction

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based on heuristic

inferred from title

author name string

Jaime J Smith

1

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Theodore R Cummins

2

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Sujith Alphy

3

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Kenneth M Blumenthal

4

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Europe PubMed Central

PubMed publication ID

18 September 2017

language of work or name

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publication date

5 March 2007

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Europe PubMed Central

PubMed publication ID

18 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

18 September 2017

282

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Europe PubMed Central

PubMed publication ID

18 September 2017

17

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

12687-12697

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Voltage sensors in domains III and IV, but not I and II, are immobilized by Na+ channel fast inactivation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Sodium channel mutations in paramyotonia congenita uncouple inactivation from activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Coupling interactions between voltage sensors of the sodium channel as revealed by site-specific measurements

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Shaker potassium channel gating. III: Evaluation of kinetic models for activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Activation of Shaker potassium channels. III. An activation gating model for wild-type and V2 mutant channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Molecular determinants of high affinity binding of alpha-scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na+ channel alpha subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

A specific interaction between the cardiac sodium channel and site-3 toxin anthopleurin B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Voltage sensor-trapping: enhanced activation of sodium channels by beta-scorpion toxin bound to the S3-S4 loop in domain II.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Neutralization of gating charges in domain II of the sodium channel alpha subunit enhances voltage-sensor trapping by a beta-scorpion toxin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Structure and function of the voltage sensor of sodium channels probed by a beta-scorpion toxin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Two tarantula peptides inhibit activation of multiple sodium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Direct evidence that receptor site-4 of sodium channel gating modifiers is not dipped in the phospholipid bilayer of neuronal membranes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Mapping the receptor site for hanatoxin, a gating modifier of voltage-dependent K+ channels.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Molecular surface of tarantula toxins interacting with voltage sensors in K(v) channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Arg-14 loop of site 3 anemone toxins: effects of glycine replacement on toxin affinity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Down-regulation of Na channel expression by A23187 in N1E-115 neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Distinct transient outward potassium current (Ito) phenotypes and distribution of fast-inactivating potassium channel alpha subunits in ferret left ventricular myocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Subtype specificity of scorpion beta-toxin Tz1 interaction with voltage-gated sodium channels is determined by the pore loop of domain 3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

A membrane-access mechanism of ion channel inhibition by voltage sensor toxins from spider venom

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Solution structure and lipid membrane partitioning of VSTx1, an inhibitor of the KvAP potassium channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Solution structure and functional characterization of SGTx1, a modifier of Kv2.1 channel gating

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

SGTx1, a Kv channel gating-modifier toxin, binds to the interfacial region of lipid bilayers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

A hot spot for the interaction of gating modifier toxins with voltage-dependent ion channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Hanatoxin modifies the gating of a voltage-dependent K+ channel through multiple binding sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

ProTx-I and ProTx-II: gating modifiers of voltage-gated sodium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610462200

21 January 2018

Identifiers

10.1074/JBC.M610462200

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

ResearchGate publication ID

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