(Q40166680)

18 September 2017

title

Disruption of the GDNF binding site in NCAM dissociates ligand binding and homophilic cell adhesion (English)

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18 September 2017

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4

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18 September 2017

Dan Sjöstrand

1

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18 September 2017

Jonas Carlsson

series ordinal

2

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18 September 2017

Gustavo Paratcha

series ordinal

3

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18 September 2017

Carlos F Ibáñez

series ordinal

5

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18 September 2017

language of work or name

English

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publication date

23 February 2007

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Journal of Biological Chemistry

18 September 2017

published in

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18 September 2017

volume

282

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18 September 2017

issue

17

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18 September 2017

page(s)

12734-12740

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Continuing trials of GDNF in Parkinson's disease

18 September 2017

cites work

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Multiple actions of systemic artemin in experimental neuropathy

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GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF

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Characterization of a multicomponent receptor for GDNF.

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TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret.

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GFRalpha3 is an orphan member of the GDNF/neurturin/persephin receptor family

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Multiple GPI-anchored receptors control GDNF-dependent and independent activation of the c-Ret receptor tyrosine kinase

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GDNF signalling through the Ret receptor tyrosine kinase

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Functional receptor for GDNF encoded by the c-ret proto-oncogene

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The neural cell adhesion molecule NCAM is an alternative signaling receptor for GDNF family ligands

21 January 2018

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The GDNF family: signalling, biological functions and therapeutic value

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Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis

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GDNF and GFRalpha1 promote formation of neuronal synapses by ligand-induced cell adhesion

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GDNF is a chemoattractant factor for neuronal precursor cells in the rostral migratory stream

21 January 2018

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Glial cell line-derived neurotrophic factor-induced signaling in Schwann cells.

21 January 2018

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X-ray structure of glial cell-derived neurotrophic factor at 1.9 A resolution and implications for receptor binding

21 January 2018

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The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation

21 January 2018

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Structure of artemin complexed with its receptor GFRalpha3: convergent recognition of glial cell line-derived neurotrophic factors

21 January 2018

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Functional mapping of receptor specificity domains of glial cell line-derived neurotrophic factor (GDNF) family ligands and production of GFRalpha1 RET-specific agonists

21 January 2018

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Distinct structural elements in GDNF mediate binding to GFRalpha1 and activation of the GFRalpha1-c-Ret receptor complex

21 January 2018

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Determinants of ligand binding specificity in the glial cell line-derived neurotrophic factor family receptor alpha S.

21 January 2018

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Molecular modeling of the extracellular domain of the RET receptor tyrosine kinase reveals multiple cadherin-like domains and a calcium-binding site

21 January 2018

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Structure and Interactions of NCAM Ig1-2-3 Suggest a Novel Zipper Mechanism for Homophilic Adhesion

21 January 2018

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Identification of a cDNA clone that contains the complete coding sequence for a 140-kD rat NCAM polypeptide

21 January 2018

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Organization of the neural cell adhesion molecule (N-CAM) gene: alternative exon usage as the basis for different membrane-associated domains

21 January 2018

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Identification of N-glycosylation sites of the murine neural cell adhesion molecule NCAM by MALDI-TOF and MALDI-FTICR mass spectrometry

21 January 2018

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Characterization of N-glycans from mouse brain neural cell adhesion molecule

21 January 2018

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Neural cell adhesion molecule (N-CAM) homophilic binding mediated by the two N-terminal Ig domains is influenced by intramolecular domain-domain interactions.

21 January 2018

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Mechanism of homophilic adhesion by the neural cell adhesion molecule: use of multiple domains and flexibility

21 January 2018

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Topology of cell adhesion molecules

21 January 2018

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Visualization of neural cell adhesion molecule by electron microscopy

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M701588200

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18 September 2017

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