(Q40171398)

English

The propeptide of cruzipain--a potent selective inhibitor of the trypanosomal enzymes cruzipain and brucipain, and of the human enzyme cathepsin F.

scientific article published on March 2007

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scholarly article

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Europe PubMed Central

PubMed publication ID

18 September 2017

The propeptide of cruzipain--a potent selective inhibitor of the trypanosomal enzymes cruzipain and brucipain, and of the human enzyme cathepsin F. (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

author name string

Flavia C G Reis

1

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Europe PubMed Central

PubMed publication ID

18 September 2017

Tatiana F R Costa

2

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Europe PubMed Central

PubMed publication ID

18 September 2017

Traian Sulea

3

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Alessandra Mezzetti

4

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Julio Scharfstein

5

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Dieter Brömme

6

1 reference

Europe PubMed Central

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18 September 2017

Robert Ménard

7

1 reference

Europe PubMed Central

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18 September 2017

Ana Paula C A Lima

8

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PubMed publication ID

18 September 2017

language of work or name

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publication date

1 March 2007

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Europe PubMed Central

PubMed publication ID

18 September 2017

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Europe PubMed Central

PubMed publication ID

18 September 2017

274

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18 September 2017

5

1 reference

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18 September 2017

1224-1234

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Cysteine proteases of parasitic organisms

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Trypanosoma brucei: killing of bloodstream forms in vitro and in vivo by the cysteine proteinase inhibitor Z-phe-ala-CHN2.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

The major cysteine proteinase of Trypanosoma cruzi: a valid target for chemotherapy of Chagas disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

The cysteine protease of Trypanosoma cruzi as a model for antiparasite drug design

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

The crystal structure of cruzain: a therapeutic target for Chagas' disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Structure-based design, synthesis and evaluation of conformationally constrained cysteine protease inhibitors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Vinyl Sulfones as Mechanism-Based Cysteine Protease Inhibitors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Development of alpha-keto-based inhibitors of cruzain, a cysteine protease implicated in Chagas disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Processing and activation of lysosomal proteinases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

The proregion of cathepsin L is required for proper folding, stability, and ER exit

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

The lysosomal proenzyme receptor that binds procathepsin L to microsomal membranes at pH 5 is a 43-kDa integral membrane protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Proregion structure of members of the papain superfamily. Mode of inhibition of enzymatic activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Design of noncovalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Inhibition of trypanosomal cysteine proteinases by their propeptides.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

The determination of enzyme inhibitor constants

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Cell signalling and Trypanosoma cruzi invasion

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Cathepsins F and S block HDL3-induced cholesterol efflux from macrophage foam cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Cathepsin V, a novel and potent elastolytic activity expressed in activated macrophages.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Role for cathepsin F in invariant chain processing and major histocompatibility complex class II peptide loading by macrophages

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Cysteine protease cathepsin F is expressed in human atherosclerotic lesions, is secreted by cultured macrophages, and modifies low density lipoprotein particles in vitro.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Human cathepsin F. Molecular cloning, functional expression, tissue localization, and enzymatic characterization

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Expression of human cathepsin K in Pichia pastoris and preliminary crystallographic studies of an inhibitor complex

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Cysteine protease isoforms from Trypanosoma cruzi, cruzipain 2 and cruzain, present different substrate preference and susceptibility to inhibitors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

The crystal structure of human procathepsin K

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

18th Sir Hans Krebs lecture. Knowledge-based protein modelling and design

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05666.X

21 January 2018

Identifiers

10.1111/J.1742-4658.2007.05666.X

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

ResearchGate publication ID

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